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:: Volume 25, Issue 3 (10-2023) ::
J Gorgan Univ Med Sci 2023, 25(3): 62-67 Back to browse issues page
Effect of a Combination of Dexamethasone and Lidocaine on the Duration of Digital Nerve Block of Orthopedic Surgery
Arazberdi Ghourchaei * 1, Godarz Koshki2 , Seyedeh Mahrokh Alinaghimaddah3
1- Associate Professor in Anesthesia, Clinical Research Development Unit (CRDU), 5th Azar Hospital, Golestan University of Medical Sciences, Gorgan, Iran. , drghourchaei@yahoo.com
2- Resident in Anesthesia, Clinical Research Development Unit (CRDU), 5th Azar Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
3- Assistant Professor in Anesthesia, Clinical Research Development Unit (CRDU), 5th Azar Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
Abstract:   (744 Views)

Background and Objective: Lidocaine is the most effective anesthetic and a valuable drug for nerve pain control and management. Dexamethasone is commonly used to prevent postoperative nausea and vomiting. Dexamethasone, together with a local anesthetic, enhances the peripheral nerve block. Therefore, this study was conducted to compare the duration of anesthesia and analgesia effects after surgery in 2 anesthesia methods.
Methods: This descriptive-analytical study was conducted on 50 patients aged 18 to 70 years who were candidates for orthopedic surgery and visited the 5th Azar Medical Training Center, Gorgan, Iran during 2021. The sample was selected via convenience sampling and by checking the inclusion criteria. In group 1, 10 ml of Lidocaine 1%, and in group 2, 8 ml of 1% Lidocaine and 2 ml of dexamethasone were used as infiltration in the operation site. The average onset of analgesia and the duration of analgesia as well as postoperative pain between both anesthesia methods were determined and compared with the visual analog scale.
Results: The average duration of anesthetic effect was significantly higher in group 2 (P<0.05). In addition, the average pain duration of the patients of group 2 had a downward trend from the time of entry to when they exited the recovery room (P<0.05).
Conclusion: The combination of dexamethasone and Lidocaine increased the duration of finger nerve block effect and analgesia after surgery.

Keywords: Nerve Block [MeSH], Lidocaine [MeSH], Dexamethasone [MeSH]
Article ID: Vol25-35
Full-Text [PDF 576 kb]   (1052 Downloads)    
Type of Study: Original Articles | Subject: Anesthesiology and Pain
References
1. De Buck F, Devroe S, Missant C, Van de Velde M. Regional anesthesia outside the operating room: indications and techniques. Curr Opin Anaesthesiol. 2012 Aug; 25(4): 501-507. doi: 10.1097/ACO.0b013e3283556f58. [DOI] [PubMed]
2. Knoop K, Trott A, Syverud S. Comparison of digital versus metacarpal blocks for repair of finger injuries. Ann Emerg Med. 1994 Jun; 23(6): 1296-300. doi: 10.1016/s0196-0644(94)70355-8. [DOI] [PubMed]
3. Aschersleben G, Gehrke J, Prinz W. Tapping with peripheral nerve block. a role for tactile feedback in the timing of movements. Exp Brain Res. 2001 Feb; 136(3): 331-39. doi: 10.1007/s002210000562. [DOI] [PubMed]
4. Napier A, Howell DM, Taylor A. Digital Nerve Block. StatPearls Publishing. 2023. [Link]
5. Collins PAW, DiDonato RM, Thomson K, Brazil M. A proof-of-concept assessment in healthy volunteers of stimulated skin wrinkling to determine the presence or absence of digital nerve blockade. Can J Anaesth. 2021 Aug; 68(8): 1279-80. doi: 10.1007/s12630-021-02010-5. [DOI] [PubMed]
6. De Oliveira GS Jr, Almeida MD, Benzon HT, McCarthy RJ. Perioperative single dose systemic dexamethasone for postoperative pain: a meta-analysis of randomized controlled trials. Anesthesiology. 2011 Sep; 115(3): 575-88. doi: 10.1097/ALN.0b013e31822a24c2. [DOI] [PubMed]
7. Dominguez JE, Habib AS. Prophylaxis and treatment of the side-effects of neuraxial morphine analgesia following cesarean delivery. Curr Opin Anaesthesiol. 2013 Jun; 26(3): 288-95. doi: 10.1097/ACO.0b013e328360b086. [DOI] [PubMed]
8. Le TP, Gan TJ. Update on the management of postoperative nausea and vomiting and postdischarge nausea and vomiting in ambulatory surgery. Anesthesiol Clin. 2010 Jun; 28(2): 225-49. doi: 10.1016/j.anclin.2010.02.003. [DOI] [PubMed]
9. Ailes D, Waseem M. Regional Anesthesia (Nerve Blocks). In: Ganti L, editor. Atlas of Emergency Medicine Procedures. New York: Springer. 2016; pp: 511-23. doi: 10.1007/978-1-4939-2507-0_89 [DOI]
10. Osada R, Zukawa M, Seki E, Kimura T. Continuous peripheral nerve block in forearm for severe hand trauma. Hand Surg. 2011; 16(3): 239-44. doi: 10.1142/S0218810411005485. [DOI] [PubMed]
11. Kirksey MA, Haskins SC, Cheng J, Liu SS. Local Anesthetic Peripheral Nerve Block Adjuvants for Prolongation of Analgesia: A Systematic Qualitative Review. PLoS One. 2015 Sep; 10(9): e0137312. doi: 10.1371/journal.pone.0137312. [DOI] [PubMed]
12. Bailard NS, Ortiz J, Flores RA. Additives to local anesthetics for peripheral nerve blocks: Evidence, limitations, and recommendations. Am J Health Syst Pharm. 2014 Mar; 71(5): 373-85. doi: 10.2146/ajhp130336. [DOI] [PubMed]
13. Alboeh M, Tabasi M, Emani F, Entezry S. [The Effect of Adding Dexamethasone to Sodium bicarbonate and Lidocaine 1.5% on the Onset and Duration of Axillary Block as well as Post Operative Analgesia in the Upper Extremity Procedures]. RJMS. 2009; 16(6). [Article in Persian] [View at Publisher]
14. Biavaschi Silva G, De La Côrte FD, Brass KE, Azevedo MS, Dau S, et al. Duration and Efficacy of Different Local Anesthetics on the Palmar Digital Nerve Block in Horses. Journal of Equine Veterinary Science. 2015 Sep; 35(9): 749-55. doi :10.1016/j.jevs.2015.07.013. [Link] [DOI]
15. Hazrati E, Afsahi M, Namazi M, Kheradmand B, Rafiei M. Effect on analgesia duration and pain intensity of adding dexamethasone to lidocaine in digital nerve block in patients with finger trauma. Hand Surg Rehabil. 2021 Dec; 40(6): 794-98. doi: 10.1016/j.hansur.2021.08.007. [DOI] [PubMed]
16. Williams BA, Murinson BB, Grable BR, Orebaugh SL. Future considerations for pharmacologic adjuvants in single-injection peripheral nerve blocks for patients with diabetes mellitus. Reg Anesth Pain Med. 2009 Sep-Oct; 34(5): 445-57. doi: 10.1097/AAP.0b013e3181ac9e42. [DOI] [PubMed]
17. Shrestha BR, Maharjan SK, Shrestha S, Gautam B, Thapa C, Thapa PB, et al. Comparative study between tramadol and dexamethasone as an admixture to bupivacaine in supraclavicular brachial plexus block. JNMA J Nepal Med Assoc. 2007 Oct-Dec; 46(168): 158-64. [PubMed]
18. Devor M. Sodium channels and mechanisms of neuropathic pain. J Pain. 2006 Jan; 7(1 Suppl 1): S3-S12. doi: 10.1016/j.jpain.2005.09.006. [DOI] [PubMed]
19. Hewson D, Bedforth N, McCartney C, Hardman J. Dexamethasone and peripheral nerve blocks: back to basic (science). Br J Anaesth. 2019 Apr; 122(4): 411-12. doi: 10.1016/j.bja.2019.02.004. [DOI] [PubMed]
20. Bruccoleri A, Pennypacker KR, Harry GJ. Effect of dexamethasone on elevated cytokine mRNA levels in chemical-induced hippocampal injury. J Neurosci Res. 1999 Sep; 57(6): 916-26. [PubMed]
21. Benzon HT, Chew TL, McCarthy RJ, Benzon HA, Walega DR. Comparison of the particle sizes of different steroids and the effect of dilution: a review of the relative neurotoxicities of the steroids. Anesthesiology. 2007 Feb; 106(2): 331-38. doi: 10.1097/00000542-200702000-00022. [DOI] [PubMed]
22. Kayalha H, Ahmadi Gooraji S, Parsa H, Beigom Khezri M. The Analgesic Efficacy of Low Dose Dexamethasone Added to Bupivacaine in Ilioinguinal and Iliohypogastric Nerves Block in Patients Undergoing Inguinal Hernia Surgery under Spinal Anesthesia. J Adv Med Biomed Res 2019; 27(124): 16-22. doi: 10.30699/jambs.27.124.16. [View at Publisher] [DOI]
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Ghourchaei A, Koshki G, Alinaghimaddah S M. Effect of a Combination of Dexamethasone and Lidocaine on the Duration of Digital Nerve Block of Orthopedic Surgery. J Gorgan Univ Med Sci 2023; 25 (3) :62-67
URL: http://goums.ac.ir/journal/article-1-4306-en.html


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Volume 25, Issue 3 (10-2023) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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