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Jorjani Biomed J 2020, 8(2): 38-47 |
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salehi O R, ghabezi S, Khajehlandi A, Mohammadi A. Interactive effect of aerobic training and estrogen consumption on serum levels of catalase and glutathione peroxidase enzymes in. Jorjani Biomed J 2020; 8 (2) :38-47
URL: http://goums.ac.ir/jorjanijournal/article-1-729-en.html
URL: http://goums.ac.ir/jorjanijournal/article-1-729-en.html
1- Department of Physical Education and Sport Sciences, University of Kurdistan, Sanandaj, Iran
2- Department of Physical Education and Sport Sciences, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
3- Department of Physical Education and Sport Sciences, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran ,a.khajehlandi@yahoo.com
2- Department of Physical Education and Sport Sciences, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
3- Department of Physical Education and Sport Sciences, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran ,
Abstract: (6559 Views)
Background and objective: Aging and menopause are associated with decreased antioxidant function, however, the role of exercise and estrogen consumption in the health of these people has been shown. The aim of the present study was to investigate the interactive effect of aerobic training (AT) and estrogen (Es) on serum levels of catalase (Cat) and glutathione peroxidase (Gpx) enzymes in ovariectomized rats.
Material and Methods: In this experimental study, 45 ovariectomized rats were randomly divided into 5 groups of 9 rats, including (1) control (C), (2) estrogen solvent (sesame oil) (Sh), (3) AT, (4), Es,and (5) AT+Es. Rats in groups 3 and 5 were trained for eight weeks and three sessions, and groups 4 and 5 randomly received 30 micrograms of estradiol valerate daily for eight weeks. Data analysis was analyzed using one-way analysis of variance and Tukey’s post hoc test at the significance level of 0.05.
Results: Cat levels in the AT (P= 0.006), Es (P= 0.005) and AT + Es (P = 0.001) groups were significantly higher than the control group. Cat levels in the AT + Es group were also significantly higher than in the Es group (P = 0.01). Gpx levels in the AT (P = 0.001), S (P = 0.001) and AT + Es (p = 0.001) groups were significantly higher than the control group, while in the S (P = 0.001) and AT + Es (P = 0.001) groups, they were significantly higher than the AT group.
Conclusion: It seems that aerobic training combined with estrogen consumption synergistically improves the function of the antioxidant system in ovariectomized rats. However, it seems that the signaling pathway of interventions requires further study.
Material and Methods: In this experimental study, 45 ovariectomized rats were randomly divided into 5 groups of 9 rats, including (1) control (C), (2) estrogen solvent (sesame oil) (Sh), (3) AT, (4), Es,and (5) AT+Es. Rats in groups 3 and 5 were trained for eight weeks and three sessions, and groups 4 and 5 randomly received 30 micrograms of estradiol valerate daily for eight weeks. Data analysis was analyzed using one-way analysis of variance and Tukey’s post hoc test at the significance level of 0.05.
Results: Cat levels in the AT (P= 0.006), Es (P= 0.005) and AT + Es (P = 0.001) groups were significantly higher than the control group. Cat levels in the AT + Es group were also significantly higher than in the Es group (P = 0.01). Gpx levels in the AT (P = 0.001), S (P = 0.001) and AT + Es (p = 0.001) groups were significantly higher than the control group, while in the S (P = 0.001) and AT + Es (P = 0.001) groups, they were significantly higher than the AT group.
Conclusion: It seems that aerobic training combined with estrogen consumption synergistically improves the function of the antioxidant system in ovariectomized rats. However, it seems that the signaling pathway of interventions requires further study.
Keywords: Training , Estrogen [MeSH], Catalase [MeSH], Glutathione peroxidase [MeSH], Ovariectomy [MeSH]
Type of Article: Original article |
Subject:
Health
Received: 2020/01/17 | Accepted: 2020/05/1 | Published: 2020/06/30
Received: 2020/01/17 | Accepted: 2020/05/1 | Published: 2020/06/30
References
1. Rosner B, Colditz GA. Age at menopause: imputing age at menopause for women with a hysterectomy with application to risk of postmenopausal breast cancer. Ann Epidemiol.2011;21(6):450-60. [view at publisher] [DOI] [Google Scholar]
2. Sarkaki, A., Amani, R., Badavi, M., Safahani, M., Aligholi, H. Effect of ovariectomy on reference memory version of Morris water maze in young adult rats. Iran Biomed J. 2008; 12 (2): 123-128. [Google Scholar]
3. Albayrak A, Uyanik MH, Odabasoglu F, Halici Z, Uyanik A, Bayir Y, et al. The effects of diabetes and/or polymicrobial sepsis on the status of antioxidant enzymes and pro-inflammatory cytokines on heart, liver, and lung of ovariectomized rats. J Surg Res. 2011;169(1):67-75. [view at publisher] [DOI] [Google Scholar]
4. Stray-Gundersen J, Chapman RF, Levine BD. Living high-training low altitude training improves sea level performance in male and female elite runners. J Appl Physiol. 001;91(3):1113-20. [view at publisher] [DOI] [Google Scholar]
5. Behr, G.A., Schnorr, C.E., Moreira, J.C.F. Increased blood oxidative stress in experimental menopause rat model: The effects of vitamin A low-dose supplementation upon antioxidant status in bilateral ovariectomized rats. Fundam Clin Pharmacol. 2012; 26(2): 235-249. [view at publisher] [DOI] [Google Scholar]
6. Maroti T, Sobocanec S, Safranko Z, Saric A, Kusic B, Balog T. Sensitivity to oxidative stress sex matters. Med Sci 2010;35:59-68. [view at publisher] [Google Scholar]
7. Vaishali s, Sanjeev s, Neelima s, Shaila s . Status of antioxidant enzymes and trace metals in postmenopausal women. J Obstet Gynecol India. 2005;55:64-6. [Google Scholar]
8. Utian WH, Archer DF, Bachmann GA, Gallagher C, Grodstein F, Heiman JR, et al. Estrogen and progestogen use in postmenopausal women: 2008 position statement of The North American Menopause Society. Menopause 2008; 15(4): 584-602. [view at publisher] [DOI] [Google Scholar]
9. Pachman DR, Jones JM, Loprinzi CL. Management of menopause-associated vasomotor symptoms: Current treatment options, challenges and future directions. Int J Womens Health. 2010;2:123. [view at publisher] [DOI] [Google Scholar]
10. Abbsidarehbidi M, Bambaeichi E. Comparison of the Effects of Aerobic Training with Vitamin C and Estradiol on Markers of the Liver among Ovariectomized and Normal Rats . sjimu. 2019; 27 (2) :198-209. [view at publisher] [DOI] [Google Scholar]
11. Babaei P, Damirchi A, Honarmand F, Mehdizadeh R. The Effect of Ovariectomy and Estrogen Replacement on Body Weight and Visceral Adipose Tissue in Rats. Iran J Endocrinol Metab. 2009;11(1). 2009; 11 (1) :89-95. [view at publisher] [Google Scholar]
12. Hejazi M, nezamdoost Z, Saghebjoo M. Effect of Twelve Weeks of Aerobic Training on Serum Levels of Leptin, Vaspin and Some Indicators of Oxidative Stress in Obese Middle-Aged Women. Iranian Journal of Endocrinology and Metabolism. 2014; 16 (2) :111-118. [view at publisher] [Google Scholar]
13. Ghorbanian B, Azali alamdari K, Saberi Y, Shokrolahi F, Mohamadi H. Effect of an Incremental Interval Endurance Rope-Training Program on Antioxidant Biomarkers and Oxidative Stress in Non-Active Women. SJNMP. 2018; 4 (1) :29-40 [view at publisher] [Google Scholar]
14. Ascensão A, Magalhães J, Soares J, Oliveira J, Duarte JA. Exercise and cardiac oxidative stress. Rev Port Cardiol 2003; (5):651-78.
15. Goto, S., & Radak, Z. (2013). Implications of oxidative damage to proteins and DNA in aging and its intervention by caloric restriction and exercise. J Sport Heal Sci. 2013;2(2):75-80. [view at publisher] [DOI] [Google Scholar]
16. Sadat-Hoseini S K, Dabidi Roshan V. The effect of six weeks of voluntary wheel running exercise on hepatic superoxide dismutase levels and apoptosis-inducing factor after doxorubicin administration in aging model rats. Feyz. 2018; 22 (3) :267-273 [view at publisher] [Google Scholar]
17. Kaikhosravi, F., Daryanoosh, F., Koushki Jahromi, M., Neamati, J. Psycho- physiologic Effects of High Intensity Interval Trainings in Aged Ovariectomized Rats: a Pilot Study. Report of Health Care, 2019; 5(3): 1-7. [view at publisher] [Google Scholar]
18. Choi SB, Jang JS, Park S. Estrogen and Exercise May Enhance β -Cell Function and Mass via Insulin Receptor Substrate 2 Induction in Ovariectomized Diabetic Rats. Endocrinology 2005; 146: 4786-94. [view at publisher] [DOI] [Google Scholar]
19. Latour MG, Shinoda M, Lavoie JM. Metabolic effects of physical training in ovariectomized and hyperestrogenic rats. Journal of applied physiology. 2001;90(1):235-41. [view at publisher] [DOI] [Google Scholar]
20. Aebi H. Catalase in vitro. InMethods in enzymology. 1984 ;. 105, pp. 121-126). Academic Press. [view at publisher] [DOI] [Google Scholar]
21. Ursini F, Maiorino M, Gregolin C. The selenoenzyme phospholipid hydroperoxide glutathione peroxidase. Biochimica et Biophysica Acta (BBA)-General Subjects. 1985;839(1):62-70. [view at publisher] [DOI] [Google Scholar]
22. Hsu MC, Wang TS, Liu YP, Liu CF. Effects of Baduanjin exercise on oxidative stress and antioxidant status and improving quality of life among middle-aged women. The American journal of Chinese medicine. 2008;36(05):815-26. [view at publisher] [DOI] [Google Scholar]
23. Khassaf M, McArdle A, Esanu C, Vasilaki A, McArdle F, Griffiths RD, Brodie DA, Jackson MJ. Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle. J Physiol. 2003;549(2):645-52. [view at publisher] [DOI] [Google Scholar]
24. Venojärvi M, Korkmaz A, Wasenius N, Manderoos S, Heinonen OJ, Lindholm H, Aunola S, Eriksson JG, Atalay M. 12 weeks' aerobic and resistance training without dietary intervention did not influence oxidative stress but aerobic training decreased atherogenic index in middle-aged men with impaired glucose regulation. Food Chem Toxicol. 2013;61:127-35. [view at publisher] [DOI] [Google Scholar]
25. Afzalpour ME, Gharakhanlou R, Gaeini AA, Mohebbi H, Hedayati M, Khazaei M. The effects of aerobic exercises on the serum oxidized LDL and total antioxidant capacity in non-active men. CVD Prev Control 2008;3(2):77-82. [view at publisher] [DOI] [Google Scholar]
26. De Castro MA, Cavalcanti Neto FF, Lima LM, Da Silva FM, De Oliveira RJ, Zanesco A. Production of free radicals and catalase activity during acute exercise training in young men. Biology of Sport. 2009;26(2):113-118. [DOI] [Google Scholar]
27. Daud DM, Karim AA, Mohamad N, Hamid NA, Wan Ngah WZ. Effect of exercise intensity on antioxidant enzymatic activities in sedentary adults. Malaysian Journal of Biochemistry and Molecular Biology. 2006;13(1):37-47. [Google Scholar]
28. Fisher-Wellman K, Bloomer RJ. Acute exercise and oxidative stress: a 30 year history. Dynamic medicine. 2009;8(1):1-25 [view at publisher] [DOI] [Google Scholar]
29. Modir M, Daryanoosh F, Mohamadi M, Firouzmand H. The effects of short and middle times aerobic exercise with high intensities on ingredients antioxidant in female Sprague Dawley rats. medical journal of mashhad university of medical sciences. 2014;57(3):587-95. [view at publisher] [Google Scholar]
30. Hasanpour, M., Goodazi, M. T., Nouri, M. Protein Electrophoresis Pattern and Oxidative Stress Protection of Human Follicular Fluid in Fertile and Infertile Women. Iran J Obstet Gynecol Infertil [Internet]. 2019;22(9):72-84. [view at publisher] [Google Scholar]
31. Bureau I, Laporte F, Favier M, Faure H, Fields M, Favier AE, Roussel AM. No antioxidant effect of combined HRT on LDL oxidizability and oxidative stress biomarkers in treated post-menopausal women. J Am Coll Nutr. 2002;21(4):333-8. [view at publisher] [DOI] [Google Scholar]
32. Seyyed A, Farsi S, Hosseini SA, Kaka G. The Effect of Swimming Training with Curcumin Consumption on Superoxide Dismutase and Glutathione Peroxidase Levels in Alcoholic Rats' Heart Tissue. J Arch Mil Med. 2018;6(4). 1-6. [DOI] [Google Scholar]
33. Ahmadi kakavandi M, Azizbeigi K, Qeysari S F. The Effects of Progressive Resistance Training on Malondialdehyde Concentration and Superoxide Dismutase Enzyme Activity in Inactive Elderly Women. payavard. 2019; 13 (2) :151-159. [view at publisher] [Google Scholar]
34. Rabiei P, Namjoo AR. The effects of acute and chronic estrogen deficiency on glucose and lipid profile in ovariectomized rats. J Shahrekord Univ Med Sci. 2017;19(1):52-61. [view at publisher] [Google Scholar]
35. Zhao H, Niu Q, Li X, Liu T, Xu Y, Han H, Wang W, Fan N, Tian Q, Zhang H, Wang Z. Long-term resveratrol consumption protects ovariectomized rats chronically treated with D-galactose from developing memory decline without effects on the uterus. Brain research. 2012;1467:67-80. [view at publisher] [DOI] [Google Scholar]
36. Choi SB, Jang JS, Park S. Estrogen and exercise may enhance β-cell function and mass via insulin receptor substrate 2 induction in ovariectomized diabetic rats. Endocrinology. 2005;146(11):4786-94. [view at publisher] [DOI] [Google Scholar]
37. Gollisch KS, Brandauer J, Jessen N, Toyoda T, Nayer A, Hirshman MF, Goodyear LJ. Effects of exercise training on subcutaneous and visceral adipose tissue in normal-and high-fat diet-fed rats. AJP Endocrinology and Metabolism. 2009;297(2): 495-504. [view at publisher] [DOI] [Google Scholar]
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