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:: Volume 4, Number 2 (Autumn & Winter 2016 2017) ::
Hakim Jorjani J 2017, 4(2): 1-20 Back to browse issues page
Curcumin (Extracted from Tumeric) and its Therapeutic Effects
Arezou khosrojerdi, Kazem Mashayekhi, Hadi Zare Marzouni
Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:   (815 Views)

Background and Objectives:  The application of herbal medicine has been rising in recent years. Therefore, it is logical to revise and revive these traditional drugs while identifying their mechanisms of action can result in developing new treatments for many diseases. Curcumin is the most important component of Turmeric with numerous therapeutic properties. We aimed to review the anti-inflammatory and anti-microbial properties of Curcumin and introduce it as a therapeutic molecule in the present article.

Methods: In this review, 121 articles were selected from authenticated electronic resources and scientific library databases such as Pubmed, Medline, Sciencedirect, WOS, DOAJ, SID, Iranmedex, Magiran and Google Scholar search engine in which Curcumin (Turmeric) had been evaluated as a therapeutic molecule from differeny aspects.

Results: Our findings from the literature revealed that immune responses against infectious and inflammatory factors could be fascilitated by Curcumin. However, the low solubility in water and minimal bioavailability which may lead to poor absorbance from gastrointestinal tract, quick metabolization and elimination from blood circulation are the most important problems during oral consumption.

Conclusion: According to the results of the present review article, Curcumin possesses efficient anti-inflammatory, anti-microbial, anti-viral and anti-parasitic properties. However, the low bioavailability of this substance has limited its treatment properties. Nowadays, several mechanisms have been proposed to increase the bioavailability which can improve its absorption.

Keywords: Curcumin, Turmeric, Inflammation, Infection, Imuune system
Full-Text [PDF 912 kb]   (762 Downloads)    
Type of Study: Review Article | Subject: General
Received: 2016/12/26 | Accepted: 2016/12/26 | Published: 2016/12/26
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khosrojerdi A, Mashayekhi K, Zare Marzouni H. Curcumin (Extracted from Tumeric) and its Therapeutic Effects. Hakim Jorjani J. 2017; 4 (2) :1-20
URL: http://goums.ac.ir/jorjanijournal/article-1-471-en.html
Volume 4, Number 2 (Autumn & Winter 2016 2017) Back to browse issues page
مجله حکیم جرجانی jorjani
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