row

Current Research Topics and Titles

1

The simultaneous effect of Apoptin expression and IL-2 /GM-CSF overexpression on the inhibition of breast cancer cell line, MDA-MB-231 

2

Effect of Simultaneous lncRNAROR Downregulation and MEG3 Upregulation by Tumor Specific Bidirectional Expression Vector in Colon Cancer Cell Line

3

Production of anti-EGFR scFv-IRDye800CW conjugate and evaluation of its activity in recognizing EGFRoverexpressing tumors in nude mice

4

Production of an efficient microcarrier for long-lasting delivery of Glatiramer acetate

5

The Study of GBP1P1 pseudogene function in patients with breast cancer

6

Designing and expression of chimeric Syn Notch-PD1 receptor on the surface of NK cells to enhance anti-tumor activity

7

Design and production NKG2Dbased chimeric receptor in T cell with PD1 knock out to increase anti tumor efficacy

8

Evaluation of the differentation of Mous bone marrow mesenchymal stem cells into epidermal cell on collagen hydrogel in combination with multifactorial cellulose scaffold and its effect in wound healing

9

Evaluation of Matrix protein of vesicular stomatitis virus in specific apoptosis induction in MCF7 human breast cancer cell line

10

Synthesis of a enzyme sensitive micelles for targeted drug delivery of doxurobicin in MCF7 4T1 cells and mouse model

11

Design fabrication and evaluation of colorectal cancer electrochemical nanobiosensor based on a specific aptamer and composites for

12

identification of mir29a and mir21

13

Investigating the role of ABCC6P1 pseudogene in drug resistance in liver cancer cell line HepG2

14

Investigation of PANDA lncRNA expression and its target gene BCL2 in tissue samples of patients with glioblastoma

15

evaluation of aptamer-conjugated magnetic nanoparticles loaded-Paclitaxel for targeted treatment of breast cancer in invitro & in vivo conditions

16

Effect of simultaneous silencing of G1 cyclins D1 E by a tumorspecific bidirectional construct on MDAMB231 xenograft breast tumors in nude mice

17

Effect of simultaneously silencing and up-regulation of long non coding RNAs (LncRNAs) CCAT2 and GAS5 by specific bidirectional vector in HT-29 colon cancer cells

18

Investigation of the effect of NK immune cell culture supernatant on induced apoptosis in tumor organoid model of colorectal cancer

19

Preparation of metronidazole - conjugated bismuth sulfide biological nano-radiosensitzer and evaluation of its effect on MCF-7 breast cancer cells under X-Ray irradiation

20

Fluorescence detection of the laccases activity by the photoinduced electron transfer PET process

21

In silico identification of colon cancer specific miRNAs using RNAseq data analysis and evaluation of their expression with Real Time PCR

22

The effect of silencing the expression of mTORC1 complex inhibitor genes on the survival rate and protein productivity of Chinese Hamster Ovary(CHO) cell line DG44

23

studying the effect of YAP-mutated protein and p21 overexpression and Cdc25A phosphatase downregulation on protein productivity capacity in CHO cells

24

Preparation of aptameric nanocarrier for transfer of scrambledRNA to MCF7 and MDA MB231 breast cancer cell in a 3D cell culture

25

Effect of 6s RNA reduction on Cas9-GFP protein production in BL21

26

Fabrication of electrochemical sensor based on a novel synthetic nanocomposite for simulations determination of toxic lead and cadmium ions in water samples

27

Bioinformatics Identification of Specific Breast Cancer Transcription Factors and their Effects on Chimeric Survivin-hTERT Promoter Function in MCF-7 Cell Line

28

Study of expression of noncoding long RNAs in the hypoxia process in H9C2 and HCM

29

Study of blood pseudogenes oscillation and their application in breast cancer

30

Evaluation of combinatorial function of regulatory elements ; MAR,TISU,hTEE- 658 and terminatory element of beta globin gene, on transcription and translation of Erythropoietin gene in chinese hamster ovary cells

31

The effect of mir-298, mir-107 and mir-557 overexpression on the growth and protein productivity of Chinease Hamster Ovary cells

32

Synthesis and Evaluation of Magnetite-Silica core-shell Nanostructures functionalized for drug delivery to Breast Cancer Cells in vitro

33

Design and synthesis of bismuth-gold hybrid nanostructure conjugated with HEX-bound oligonucleotide as nanophotosensitizer and evaluation of its antibacterial activity

34

Study of blood miRNAs oscillations and their variations in esophagus cancer patients

35

Study of blood pseudogenes oscillation and their application in breast cancer

36

Design and construction of aptasensor for identification of SARS-CoV-2 and its clinical evaluaton with confirmed COVID-19 samples using Real-time PCR