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Effect of swimming during pregnancy on vascular endothelial growth factor level of neonatal rat kidney tissue
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Mirdar Sh   1, Jarrahi M2 , Hedayati M3 , Hajizade A4 , Hamidian Gh5 |
1- Associate Professor, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Mazandaran, Babolsar, Iran , shadmehr.mirdar@gmail.com
2- M.Sc in Exercise Physiology
3- Associate Professor, Research Institute for Endocrine Scinces, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
4- Associate Professor, Department of Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, Iran
5- Assistant Professor, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran |
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Abstract: (9094 Views) |
| Background and Objective: The kidney has a key role in homeostatic regulation. Vascular endothelial growth factor (VEGF) is essential regulator of stimulatory and inhibitory processes for neonatal, post-natal endothelial cell differentiation. This study was done to determine the effect of maternal swimming during pregnancy on VEGF level of kidney in rat pups. Methods: In this experimental study, sixteen Wistar rat dams were allocated into interventional swimming and control groups. In the first day of pregnancy, in interventional group, swimming was performed for 30 minutes a day and 5 minutes every day was added until the time of training gradually reached to one hour per workout. Dams swimming endurance training were performed in 5 days per week for three weeks. Pups’ kidneys were removed two days after birth and kindney tissue VEGF level was determined using ELISA method. Results: Kidney tissue VEGF level in interventional swimming group (133.13 pg/ml) was significantly increased in compared to controls (48.19 pg/ml) (P<0.05). Conclusion: Swimming endurance training increases the pups’ kidney VEGF level. |
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| Keywords: Vascular endothelial growth factor, Swimming, Pregnancy, Kidney, Rat |
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Full-Text [PDF 256 kb]
[English Abstract]
(13354 Downloads)
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Type of Study: Short Communication |
Subject:
Physiology
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