:: Volume 6, Issue 2 (Autumn & Winter 2004) ::
J Gorgan Univ Med Sci 2004, 6(2): 103-106 Back to browse issues page
Necrotizing Histiocytic Lymphadenitis: Report of two cases (Kikuchi-Fujimoto disease)
M.Sharbatdaran (MD) * 1, Sh.Shefaee (MD) , G.Joghataie (M.D)
Abstract:   (24265 Views)
Kikuchi-Fujimoto disease is a necrotizing Lymphadenitis with benign self-limit process in young women with fever, cervical lymphadenopathy and increased ESR with leukopenia. In this report we introduce 2 females with Kikuchi-Fujimoto disease. The first patient was a 31 years old lady with fever and unilateral cervical lymphadenopathy weight loss from 20 days age. In paraclinical findings ESR=50 mm/hr Hb=10 gr/dl. WBC count was 5300/µl bone marrow aspiration and biopsy with lymph node was done. The histopathologic diagnosis was Kikuchi-Fujimoto (Necrotizing Lymphadenitis). The 2nd patient was a lady with 35 years old and painful neck mass (Behind the sterno-clido mastoid) from 1.5-month age with fever and chill. In paraclinical findings ESR=52 mm/hr WBC 5500/µl, CRP++ lymph node biopsy was done the histopathologic diagnosis was Kikuchi-Fujimoto necrotizing Lymphadenitis. Therefore Kikuchi disease is a important differential diagnosis in young patients especially women with cervical lymphadenopathy and fever (FUO).
Keywords: Kikuchi-Fujimoto disease, Necrotizing lymphadenitis, Lymphadenopathy
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Type of Study: Case Report | Subject: General
* Corresponding Author Address: Department of Pathology, Babol University of Medical Sciences. sharbatdaran@yahoo.com


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Volume 6, Issue 2 (Autumn & Winter 2004) Back to browse issues page