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:: Volume 18, Issue 1 (3-2016) ::
J Gorgan Univ Med Sci 2016, 18(1): 69-77 Back to browse issues page
Effect of eight weeks of endurance and resistance training on serum adiponectin and Insulin resistance index of inactive elderly men
Mir E1 , Attarzadeh Hosseini SR * 2, Hejazi K1 , Mir Sayeedi M3
1- Ph.D Candidate in Sport Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
2- Professor in Sport Physiology, Faculty of Sports Sciences, Ferdowsi University of Mashhad, Mashhad, Iran , attarzadeh@um.ac.ir
3- M.Sc in Sport Physiology, Kalaleh Branch, Islamic Azad University, Kalaleh, Iran
Abstract:   (12900 Views)

Background and Objective: Adiponectin is one of the adiposaitocines which secret from adipose tissue and is very effective in the pathogenesis of obesity and its associated disorders, especially in elderly people who are at risk for cardiovascular disease. This study was carried out to evaluate the effect of eight weeks of endurance and resistance training on adiponectin level, insulin resistance index in inactive elderly men. Methods: In this quasi-experimental study, 24 inactive elderly men were non-randomly divided into interventional and control groups. The combined training included endurance training (with intensity of 60-70% of maximum heart rate reserve) and resistance training (with intensity of 70% one repetition maximum). The training performed 3 times per week (one hour session) for 8 weeks. Results: The eight weeks of combined training increased the adiponectin level in interventional group compared to the controls (P<0.05). Insulin and FBS levels, insulin resistance index, and body fat percentage significantly reduced in interventional group compared to the controls (P<0.05). Conclusion: The eight weeks of combined training increases the adiponectin level and reduces insulin resistance in elderly men.

Keywords: Elderly, Adiponectin, Insulin resistance, Endurance training, Resistance training
Full-Text [PDF 257 kb] [English Abstract]   (14684 Downloads) |   |   Abstract (HTML)  (319 Views)  
Type of Study: Original Articles | Subject: Rehabilitation
References
1. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006 Nov; 3(11):e442.
2. Sumin AN, Gaĭfulin RA, Bezdenezhnykh AV, Mos'kin MG, Korok EV, Karpovich AV, et al. [Prevalence of multifocal atherosclerosis in different age groups]. Kardiologiia. 2012; 52(6):28-34. [Article in Russian]
3. Bashiri J. [Effect of acute endurance exercise on serum adiponectin levels among elderly overweight men]. Med J Tabriz Univ Med Sci. 2014; 36(1): 10-15. [Article in Persian]
4. Barzilai N, Banerjee S, Hawkins M, Chen W, Rossetti L. Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. J Clin Invest. 1998 Apr; 101(7): 1353-61. doi:10.1172/JCI485
5. Buizert PJ, van Schoor NM, Lips P, Deeg DJ, Eekhoff EM. Lipid levels: a link between cardiovascular disease and osteoporosis? J Bone Miner Res. 2009 Jun;24(6):1103-9. doi:10.1359/jbmr.081262
6. Lau DC, Dhillon B, Yan H, Szmitko PE, Verma S. Adipokines: molecular links between obesity and atheroslcerosis. Am J Physiol Heart Circ Physiol. 2005 May; 288(5):H2031-41.
7. Abbasi F, Brown BW Jr, Lamendola C, McLaughlin T, Reaven GM. Relationship between obesity, insulin resistance, and coronary heart disease risk. J Am Coll Cardiol. 2002 Sep; 40(5):937-43.
8. Trujillo ME, Scherer PE. Adipose tissue-derived factors: impact on health and disease. Endocr Rev. 2006 Dec;27(7):762-78.
9. Matsuzawa Y, Funahashi T, Kihara S, Shimomura I. Adiponectin and metabolic syndrome. Arterioscler Thromb Vasc Biol. 2004 Jan;24(1):29-33.
10. 10. Xu A, Yin S, Wong L, Chan KW, Lam KS. Adiponectin ameliorates dyslipidemia induced by the human immunodeficiency virus protease inhibitor ritonavir in mice. Endocrinology. 2004 Feb; 145(2):487-94.
11. Wiecek A, Adamczak M, Chudek J. Adiponectin--an adipokine with unique metabolic properties. Nephrol Dial Transplant. 2007 Apr; 22(4):981-8.
12. Goralski KB, Sinal CJ. Type 2 diabetes and cardiovascular disease: getting to the fat of the matter. Can J Physiol Pharmacol. 2007 Jan; 85(1):113-32.
13. Aminiaghdam S, Moradi F, Pejhan A, Seyedahmadi M. [Survey of relationships between serum adiponectin levels with insulin resistance, blood pressure, and cardiorespiratory function in sedentary men]. J Sabzevar Univ Med Sci. 2013; 19(4): 325-35. [Article in Persian]
14. Salehi Omran M, Jafari S. [Association of admission Insulin resistance index with early cardiac complications in non diabetic patients with acute coronary syndrome]. J Babol Uni Med Sci. 2009; 10(6): 62-6. [Article in Persian]
15. DeFronzo RA. Pathogenesis of type 2 diabetes mellitus. Med Clin North Am. 2004 Jul;88(4):787-835, ix.
16. Sironi AM, Gastaldelli A, Mari A, Ciociaro D, Positano V, Buzzigoli E, et al. Visceral fat in hypertension: influence on insulin resistance and beta-cell function. Hypertension. 2004 Aug; 44(2):127-33.
17. Fatouros IG, Tournis S, Leontsini D, Jamurtas AZ, Sxina M, Thomakos P, et al. Leptin and adiponectin responses in overweight inactive elderly following resistance training and detraining are intensity related. J Clin Endocrinol Metab. 2005 Nov;90(11): 5970-7.
18. Ligibel JA, Giobbie-Hurder A, Olenczuk D, Campbell N, Salinardi T, Winer EP, et al. Impact of a mixed strength and endurance exercise intervention on levels of adiponectin, high molecular weight adiponectin and leptin in breast cancer survivors. Cancer Causes Control. 2009 Oct; 20(8):1523-8. doi:10.1007/s10552-009-9358-3
19. Brooks N, Layne JE, Gordon PL, Roubenoff R, Nelson ME, Castaneda-Sceppa C. Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Int J Med Sci. 2006 Dec; 4(1):19-27.
20. Emamdost S, Faramarzi M, Bagheri L, Otadi K, Amiri M, Yazdani T. [The effect of combined exercise training on plasma Leptin levels and hormonal factors in overweight men]. Yafteh. 2014;16(1): 79-90. [Article in Persian]
21. Davidson LE, Hudson R, Kilpatrick K, Kuk JL, McMillan K, Janiszewski PM, et al. Effects of exercise modality on insulin resistance and functional limitation in older adults: a randomized controlled trial. Arch Intern Med. 2009 Jan; 169(2):122-31. doi:10.1001/archinternmed.2008.558
22. Ahmadizad S, Haghighi AH, Hamedinia MR. Effects of resistance versus endurance training on serum adiponectin and insulin resistance index. Eur J Endocrinol. 2007 Nov; 157(5): 625-31.
23. Asad M, Ravasi A, Faramarzi M, Gaeini A. [The effect of three types of training (endurance, resistence and combined) on rest levels of Adiponectin in overweight non - athlete men]. Sport Physiology and Management Investigations. 2011; 3(7): 89-100. [Article in Persian]
24. Hara T, Fujiwara H, Nakao H, Mimura T, Yoshikawa T, Fujimoto S. Body composition is related to increase in plasma adiponectin levels rather than training in young obese men. Eur J Appl Physiol. 2005 Aug;94(5-6):520-6.
25. Banitalebi E, Bovirhasani Baghanari H. Effect of sequence order of combined training (resistance and endurance) on strength, aerobic capacity, and body composition in older women. Middle East J Rehabil Health. 2015; 2(2):e28514. doi:10.17795/mejrh-28514
26. Park SK, Park JH, Kwon YC, Kim HS, Yoon MS, Park HT. The effect of combined aerobic and resistance exercise training on abdominal fat in obese middle-aged women. J Physiol Anthropol Appl Human Sci. 2003 May; 22(3):129-35.
27. Lee JS, Kim CG, Seo TB, Kim HG, Yoon SJ. Effects of 8-week combined training on body composition, isokinetic strength, and cardiovascular disease risk factors in older women. Aging Clin Exp Res. 2015 Apr;27(2):179-86. doi:10.1007/s40520-014-0257-4
28. Jürimäe J, Purge P, Jürimäe T. Adiponectin and stress hormone responses to maximal sculling after volume-extended training season in elite rowers. Metabolism. 2006 Jan;55(1):13-9.
29. Mason C, Foster-Schubert KE, Imayama I, Kong A, Xiao L, Bain C, et al. Dietary weight loss and exercise effects on insulin resistance in postmenopausal women. Am J Prev Med. 2011 Oct;41(4):366-75. doi:10.1016/j.amepre.2011.06.042
30. Maliqueo M, Pérez-Bravo F, Calvillán M, Piwonka V, Castillo T, Sir-Petermann T. [Relationship between leptin and insulin sensitivity in patients with polycystic ovary syndrome]. Med Clin (Barc). 1999 Oct; 113(14):526-30. [Article in Spanish]
31. Bonora E, Formentini G, Calcaterra F, Lombardi S, Marini F, Zenari L, et al. HOMA-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects: prospective data from the Verona diabetes complications study. Diabetes Care. 2002 Jul; 25(7):1135-41.
32. Robbert A, Landwehr R. The supporting history of the
33. McNair PJ, Colvin M, Reid D. Predicting maximal strength of quadriceps from submaximal performance in individuals with knee joint osteoarthritis. Arthritis Care Res (Hoboken). 2011 Feb; 63(2):216-22. doi:10.1002/acr.20368
34. Assarzade Noushabadi M, Abedi B. [Effects of combination training on insulin resistance index and some inflammatory markers in inactive men]. Horizon Med Sci. 2012;18(3): 95-105. [Article in Persian]
35. Peeri M, Akbari A, Matinhomaee H. Relationship between adiponectin and insulin resistance index in down's syndrome males after aerobic exercise. Intl J Sport Std. 2013; 3(8):852-8.
36. Sohaily S, Eizadi M, Shahedi V, Kameabnia M. The effect of resistance training on adiponectin and insulin resistance index in over weight college's students girl. International Conference on Environmental, Biomedical and Biotechnology. Singapoore. 2011; 16:102-6.
37. Balducci S, Zanuso S, Nicolucci A, Fernando F, Cavallo S, Cardelli P, et al. Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight loss. Nutr Metab Cardiovasc Dis. 2010 Oct; 20(8):608-17. doi:10.1016/j.numecd.2009.04.015
38. Klimcakova E, Polak J, Moro C, Hejnova J, Majercik M, Viguerie N, et al. Dynamic strength training improves insulin sensitivity without altering plasma levels and gene expression of adipokines in subcutaneous adipose tissue in obese men. J Clin Endocrinol Metab. 2006 Dec;91(12):5107-12.
39. Oberbach A, Tönjes A, Klöting N, Fasshauer M, Kratzsch J, Busse MW, et al. Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance. Eur J Endocrinol. 2006 Apr; 154(4): 577-85.
40. Kriketos AD, Gan SK, Poynten AM, Furler SM, Chisholm DJ, Campbell LV. Exercise increases adiponectin levels and insulin sensitivity in humans. Diabetes Care. 2004 Feb;27(2):629-30.
41. Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, Tataranni PA. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab. 2001 May;86(5): 1930-5.
42. Kraemer RR, Castracane VD. Exercise and humoral mediators of peripheral energy balance: ghrelin and adiponectin. Exp Biol Med (Maywood). 2007 Feb; 232(2):184-94.
43. Martin LJ, Woo JG, Daniels SR, Goodman E, Dolan LM. The relationships of adiponectin with insulin and lipids are strengthened with increasing adiposity. J Clin Endocrinol Metab. 2005 Jul; 90(7):4255-9.
44. Lin E, Phillips LS, Ziegler TR, Schmotzer B, Wu K, Gu LH, et al. Increases in adiponectin predict improved liver, but not peripheral, insulin sensitivity in severely obese women during weight loss. Diabetes. 2007 Mar;56(3):735-42.
45. Mazzali G, Di Francesco V, Zoico E, Fantin F, Zamboni G, Benati C, et al. Interrelations between fat distribution, muscle lipid content, adipocytokines, and insulin resistance: effect of moderate weight loss in older women. Am J Clin Nutr. 2006 Nov; 84(5):1193-9.
46. Kelly AS, Steinberger J, Olson TP, Dengel DR. In the absence of weight loss, exercise training does not improve adipokines or oxidative stress in overweight children. Metabolism. 2007 Jul; 56(7):1005-9.
47. Kobayashi J, Murase Y, Asano A, Nohara A, Kawashiri MA, Inazu A, et al. Effect of walking with a pedometer on serum lipid and adiponectin levels in Japanese middle-aged men. J Atheroscler Thromb. 2006 Aug; 13(4):197-201.
48. Højbjerre L, Rosenzweig M, Dela F, Bruun JM, Stallknecht B. Acute exercise increases adipose tissue interstitial adiponectin concentration in healthy overweight and lean subjects. Eur J Endocrinol. 2007 Nov; 157(5):613-23.
49. Jorge ML, de Oliveira VN, Resende NM, Paraiso LF, Calixto A, Diniz AL, et al. The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients with type 2 diabetes mellitus. Metabolism. 2011 Sep;60(9):1244-52. doi:10.1016/j.metabol.2011.01.006
50. Tan S, Li W, Wang J. Effects of six months of combined aerobic and resistance training for elderly patients with a long history of type 2 diabetes. J Sports Sci Med. 2012 Sep; 11(3):495-501.
51. Ho SS, Dhaliwal SS, Hills AP, Pal S. The effect of 12 weeks of aerobic, resistance or combination exercise training on cardiovascular risk factors in the overweight and obese in a randomized trial. BMC Public Health. 2012 Aug; 12:704. doi:10.1186/1471-2458-12-704
52. Parsian H, Eizadi M, Khorshidi D, Khanali F. [The effect of long-term aerobic exercise on serum adiponectin and insulin sensitivity in type 2 diabetic patients]. Pars Journal of Medical Sciences. 2013; 11(1): 41-48. [Article in Persian]
53. Sillanpää E, Laaksonen DE, Häkkinen A, Karavirta L, Jensen B, Kraemer WJ, et al. Body composition, fitness, and metabolic health during strength and endurance training and their combination in middle-aged and older women. Eur J Appl Physiol. 2009 May;106(2):285-96. doi:10.1007/s00421-009-1013-x
54. Oda K, Miyatake N, Sakano N, Saito T, Miyachi M, Tabata I, et al. Relationship between peak oxygen uptake and regional body composition in Japanese subjects. Journal of Sport and Health Science (JSHS). 2014;3(3):233-8. doi:10.1016/j.jshs.2012.11.006
55. Amani AR, Somchit MN, Konting MM, Kok LY. Relationship between body fat percent and maximal oxygen uptake among young adults. J Am Sci. 2010;6(4):1-4.
56. Choi KM, Kim JH, Cho GJ, Baik SH, Park HS, Kim SM. Effect of exercise training on plasma visfatin and eotaxin levels. Eur J Endocrinol. 2007 Oct;157(4):437-42.
57. Mendham AE, Donges CE, Liberts EA, Duffield R. Effects of mode and intensity on the acute exercise-induced IL-6 and CRP responses in a sedentary, overweight population. Eur J Appl Physiol. 2011 Jun;111(6):1035-45. doi:10.1007/s00421-010-1724-z
58. Oki K, Yamane K, Kamei N, Nojima H, Kohno N. Circulating visfatin level is correlated with inflammation, but not with insulin resistance. Clin Endocrinol (Oxf). 2007 Nov;67(5):796-800.
59. Smith JK, Dykes R, Douglas JE, Krishnaswamy G, Berk S. Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease. JAMA. 1999 May; 281(18):1722-7.
60. Church TS, Barlow CE, Earnest CP, Kampert JB, Priest EL, Blair SN. Associations between cardiorespiratory fitness and C-reactive protein in men. Arterioscler Thromb Vasc Biol. 2002 Nov; 22(11):1869-76.
61. Christopherson J, Sumer V, Kirkendall D, Jones M. Effects of exercise detraining on lipid storage in rats. Trans Ill State Acad Sci. 1999;92(3):203-9.
62. Lindegaard B, Hansen T, Hvid T, van Hall G, Plomgaard P, Ditlevsen S, et al. The effect of strength and endurance training on insulin sensitivity and fat distribution in human immunodeficiency virus-infected patients with lipodystrophy. J Clin Endocrinol Metab. 2008 Oct;93(10):3860-9. doi:10.1210/jc.2007-2733
63. Kodama S, Mia S, Yamada N, Sone H. Exercise training for ameliorating cardiovascular risk factors-focusing on exercise intensity and amount. Int J Sport Health Sci. 2006; 4(1):325-38. doi:10.5432/ijshs.4.325
64. Gomes F, Telo DF, Souza HP, Nicolau JC, Halpern A, Serrano CV Jr. [Obesity and coronary artery disease: role of vascular inflammation]. Arq Bras Cardiol. 2010 Feb;94(2):255-61, 273-9, 260-6. [Article in English, Portuguese, Spanish]
65. Taddei S, Galetta F, Virdis A, Ghiadoni L, Salvetti G, Franzoni F, et al. Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes. Circulation. 2000 Jun; 101(25):2896-901.
66. Hosseini-Kakhk SAR, Attarnejad Z, Haghighi AH. [A comparison of the effects of two aquatic exercise sessions with different duration on adiponectin and insulin resistance in women with type 2 diabetes]. J Sabzevar Univ Med Sci. 2014; 20(4): 563-72. [Article in Persian]
67. Powers S, Howley E. Exercise physiology, Theory and application to fitness and performance. 1st. New York: McGraw Hill. 2009; pp: 117-20.
68. Bastard JP, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw. 2006 Mar; 17(1):4-12.
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Mir E, Attarzadeh Hosseini SR, Hejazi K, Mir Sayeedi M. Effect of eight weeks of endurance and resistance training on serum adiponectin and Insulin resistance index of inactive elderly men. J Gorgan Univ Med Sci 2016; 18 (1) :69-77
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