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Relationship between Soil Selenium level and esophageal cancer: An ecological study in Golestan province of Iran
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Semnani Sh (MD)1   , Roshandel Gh (MD) * 2, Keshtkar AA (PhD)3 , Zendehbad A (MD)4 , Rahimzadeh H (MSc)5 , Besharat S (MD)4 , Abdolahi N (MD)6 , Moradi A (PhD)7 , Sarikhani AJ (HND)8 |
1- Associate Professor, Department of Internal Medicine, Golestan Research Center of Gastroenterology and Hepatology, Gorgan University of Medical Sciences, Gorgan, Iran
2- General Phisician, Researcher, Golestan Research Center of Gastroenterology and Hepatology, Gorgan University of Medical Sciences, Gorgan, Iran , roshandel_md@yahoo.com
3- Assistant Professor, Department of Epidemiology, Golestan Research Center of Gastroenterology and Hepatology, Gorgan University of Medical Sciences, Gorgan, Iran
4- General Phisician, Researcher, Golestan Research Center of Gastroenterology and Hepatology, Gorgan University of Medical Sciences, Gorgan, Iran
5- Academic Instructer, Department of Invironmental Health, Faculty of Paramedicine, Gorgan University of Medical Sciences, Gorgan, Iran
6- Resident of Internal Medicine, Iran University of Medical Sciences, Tehran, Iran
7- Associate Professor, Department of Virology, Golestan Research Center of Gastroenterology and Hepatology, Gorgan University of Medical Sciences, Gorgan, Iran
8- Laboratory technician, Gorgan University of Medical Sciences, Gorgan, Iran |
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Abstract: (20133 Views) |
| Background and Objective: Golestan province, located in north of Iran has been known as a high risk area for esophageal cancer. The relationship between esophageal cancer and Selenium (Se) has been assessed in previous studies. This study was conducted to assess the relationship between Soil selenium levels and development of esophageal cancer in Golestan province of Iran. Materials and Methods: In this ecologic study, Golestan province in northern Iran was divided into 135 blocks based on geographical altitude and longitude on the map. One Soil sample was collected from the center of each block. Selenium level in Soil samples was determined by flame atomic absorption spectrometry. Statistical analysis was performed by Pearson correlation and T-Student tests. Results: The mean±SD of Soil Selenium level in Golestan province was 3.7±1.61 mg/kg. There was a positive correlation between Soil level of Selenium and esophageal cancer rates in this area (P=0.03), (Pearson correlation coefficient=0.19). The Soil Selenium level for high risk and low risk area for esophageal cancer were (4.13 mg/kg) and (3.39 mg/kg) respectively (P=0.01). Conclusion: This study showed that there is high Soil Selenium level in Golestan province in north of Iran. Also it is found to be a significant positive relationship between Soil Selenium level and esophageal cancer rate in this area. |
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| Keywords: Esophageal cancer, Soil Selenium, Golestan province, Iran |
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Full-Text [PDF 707 kb]
[English Abstract]
(22086 Downloads)
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Type of Study: Original Articles |
Subject:
Gastroenterology
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Semnani Sh (MD), Roshandel Gh (MD), Keshtkar AA (PhD), Zendehbad A (MD), Rahimzadeh H (MSc), Besharat S (MD), et al . Relationship between Soil Selenium level and esophageal cancer: An ecological study in Golestan province of Iran. J Gorgan Univ Med Sci 2010; 12 (3) :51-56 URL: http://goums.ac.ir/journal/article-1-779-en.html
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