Epidemiology Specifications of Central Nervous System Tumors in the Fifth of Azar Hospital, Gorgan, Iran
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Mohammad Reza Mohammadi * 1, Shayan Mahdikia2 ![](./files/0allsites/images/pubmed20.png) |
1- Assistant Professor, Medical School, 5th Azar Hospital, Golestan University of Medical Science, Gorgan, Iran. , mr_mohammadi_md@yahoo.com 2- General Physician, Medical School, 5th Azar Hospital, Golestan University of Medical Science, Gorgan, Iran. |
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Abstract: (1212 Views) |
Background and Objective: Because of tissue variety, signs, symptoms, and higher mortality and morbidity, central nervous system (CNS) tumors are of special importance in diagnosis and treatment. Knowledge of the epidemiology of these tumors helps with health system planning. This study aimed to obtain more data on the epidemiologic specifications of these neoplasms.
Methods: This descriptive-analytical study focuses on 141 patients (58 Male and 83 female) with CNS tumors who visited the 5th Azar Hospital, Gorgan, Iran, during 2013-17. All the data were obtained from hospital medical records in the Neurosurgery and Oncology Department. All demographic data were recorded, such as age, sex, tumor type, signs, symptoms, and risk factors. In cases with incomplete data, the files were completed with interviews and phone calls.
Results: The tumors in 94 (66.6%) patients were benign, and 47 (33.3%) patients had malignant and metastatic tumors. The most common signs were headache (n=43, 30.5%) and convulsion (n=24, 17%). No relationship was found between CNS tumors, diabetes mellitus, hypertension, and hyperlipidemia.
Conclusion: Regarding the high mortality of CNS tumors, early adequate attention to signs and symptoms helps earlier diagnosis. However, more studies on larger samples are needed to find more risk factors. |
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Keywords: Epidemiology [MeSH], Nervous System Neoplasms [MeSH], Brain [MeSH], Spinal Cord [MeSH] Article ID: Vol25-34 |
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Full-Text [PDF 496 kb]
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Type of Study: Original Articles |
Subject:
Neurosurgery
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1. Mohagheghi MA, Mosavi-Jarrahi A, Malekzadeh R, Parkin M. Cancer incidence in Tehran metropolis: the first report from the Tehran Population-based Cancer Registry, 1998-2001. Arch Iran Med. 2009 Jan; 12(1): 15-23. [ PubMed] 2. Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 2016 Jun; 131(6): 803-20. doi: 10.1007/s00401-016-1545-1. [ DOI] [ PubMed] 3. World Health Organication. The top 10 causes of death. WHO. 2020 Dec. [ Link] 4. Mousavi SM, Pourfeizi A, Dastgiri S. Childhood cancer in Iran. J Pediatr Hematol Oncol. 2010 Jul; 32(5): 376-82. doi: 10.1097/MPH.0b013e3181e003f7. [ DOI] [ PubMed] 5. Ostrom QT, Adel Fahmideh M, Cote DJ, Muskens IS, Schraw JM, Scheurer ME, et al. Risk factors for childhood and adult primary brain tumors. Neuro Oncol. 2019 Nov; 21(11): 1357-75. doi: 10.1093/neuonc/noz123. [ DOI] [ PubMed] 6. Ohgaki H, Kleihues P. Epidemiology and etiology of gliomas. Acta Neuropathol. 2005 Jan; 109(1): 93-108. doi: 10.1007/s00401-005-0991-y. [ DOI] [ PubMed] 7. Kleinerman RA. Cancer risks following diagnostic and therapeutic radiation exposure in children. Pediatr Radiol. 2006 Sep; 36 (Suppl 2): 121-25. doi: 10.1007/s00247-006-0191-5. [ DOI] [ PubMed] 8. Braganza MZ, Kitahara CM, Berrington de González A, Inskip PD, Johnson KJ, Rajaraman P. Ionizing radiation and the risk of brain and central nervous system tumors: a systematic review. Neuro Oncol. 2012 Nov; 14(11): 1316-24. doi: 10.1093/neuonc/nos208. [ DOI] [ PubMed] 9. Ostrom QT, Francis SS, Barnholtz-Sloan JS. Epidemiology of Brain and Other CNS Tumors. Curr Neurol Neurosci Rep. 2021 Nov; 21(12): 68. doi: 10.1007/s11910-021-01152-9. [ DOI] [ PubMed] 10. Winn HR. Youman’s and Winn Neurological Surgery. 7th ed. Amsterdam: Elsevier. 2016; pp: 899-912. 11. Wang X, Chen JX, Zhou Q, Liu YH, Mao Q, You C, et al. Statistical Report of Central Nervous System Tumors Histologically Diagnosed in the Sichuan Province of China from 2008 to 2013: A West China Glioma Center Report. Ann Surg Oncol. 2016 Dec; 23(Suppl 5): 946-53. doi: 10.1245/s10434-016-5410-1. [ DOI] [ PubMed] 12. Zalata KR, El-Tantawy DA, Abdel-Aziz A, Ibraheim AW, Halaka AH, Gawish HH, et al. Frequency of central nervous system tumors in delta region, Egypt. Indian J Pathol Microbiol. 2011 Apr-Jun; 54(2): 299-306. doi: 10.4103/0377-4929.81607. [ DOI] [ PubMed] 13. Harmouch A, Taleb M, Lasseini A, Maher M, Sefiani S. Epidemiology of pediatric primary tumors of the nervous system: a retrospective study of 633 cases from a single Moroccan institution. Neurochirurgie. 2012 Feb; 58(1): 14-18. doi: 10.1016/j.neuchi.2012.01.005. [ DOI] [ PubMed] 14. Amirian ES, Armstrong TS, Aldape KD, Gilbert MR, Scheurer ME. Predictors of survival among pediatric and adult ependymoma cases: a study using Surveillance, Epidemiology, and End Results data from 1973 to 2007. Neuroepidemiology. 2012; 39(2): 116-24. doi: 10.1159/000339320. [ DOI] [ PubMed] 15. Mahzoni P, Mohammadizadeh F. [A five-year interval study of primary brain tumors in Alzahra Hospital in Esfahan]. Yafte. 2004; 6(1): 59-66. [Article in Persian] [ View at Publisher] 16. Reihani Kermani H. [An epidemiologic survey on brain tumors in Kerman from 1997 to 2001]. Iran South Med J 2004; 7(1): 47-53. [Article in Persian] [ View at Publisher] 17. Butowski NA. Epidemiology and diagnosis of brain tumors. Continuum (Minneap Minn). 2015 Apr; 21(2 Neuro-oncology): 301-13. doi: 10.1212/01.CON.0000464171.50638.fa. [ DOI] [ PubMed] 18. Nayak L, Lee EQ, Wen PY. Epidemiology of brain metastases. Curr Oncol Rep. 2012 Feb; 14(1): 48-54. doi: 10.1007/s11912-011-0203-y. [ DOI] [ PubMed] 19. Werneck de Carvalho LE, Sarraf JS, Semblano AA, Moreira MA, de Lemos MN, de Mello VJ, et al. Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997-2014. PLoS One. 2017 Apr; 12(4): e0174439. doi: 10.1371/journal.pone.0174439. [ DOI] [ PubMed] 20. Wrensch M, Minn Y, Chew T, Bondy M, Berger MS. Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro Oncol. 2002 Oct; 4(4): 278-99. doi: 10.1093/neuonc/4.4.278. [ DOI] [ PubMed] 21. Fisher JL, Schwartzbaum JA, Wrensch M, Wiemels JL. Epidemiology of brain tumors. Neurol Clin. 2007 Nov; 25(4): 867-90. doi: 10.1016/j.ncl.2007.07.002. [ DOI] [ PubMed]
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