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Evaluation of Anxiety and Depression Disorders in Patients with Inflammatory Bowel Disease in Golestan Province, North of Iran
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Leila Kashani1    , Firoozeh Derakhshanpour2 , Mahsa Eliasi3 , Najmeh Shahini4 , Seiedeh Maryam Hasheminasab 5 |
1- Assistant Professor of Psychiatry, Golestan Research Center of Psychiatric, Golestan University of Medical Sciences, Gorgan, Iran.
2- Child and Adolescent Psychiatrist, Associate Professor of Psychiatry, Golestan Research Center of Psychiatry, Golestan University of Medical Sciences, Gorgan, Iran.
3- General Physician, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
4- Assistant Professor of Psychiatry, Golestan Research Center of Psychiatry, Golestan University of Medical Sciences, Gorgan, Iran.
5- Master of Psychology, MPH in Epidemiology, Golestan Health Center, Golestan University of Medical Sciences, Gorgan, Iran. , hasheminasab1360@gmail.com |
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Abstract: (2166 Views) |
Background and Objective: Inflammatory bowel disease (IBD) is a common gastrointestinal disease which is associated with psychosocial factors. IBD is a gastrointestinal disease with chronic recurrence and with an uncontrolled immune response. There is no definitive treatment for IBD and treatment is based on management of inflammatory response during relapse and maintain of recovery. This study was conducted for evaluation of anxiety and depression disorders in patients with IBD in Golestan province, north of Iran during 2017.
Methods: In this descriptive-analytical study, 117 patients (67 women and 50 men) aged 17-75 years with IBD registered in IBD bank in Golestan Research Center of Gastroenterology& Hepatology (GRCGH), north of Iran during 2017. Diagnosis was made by conventional endoscopy, radiology and histological criteria. Demographic information including age, sex, race and marital status, time of diagnosis until now and duration of treatment are recorded. Hospital anxiety and depression scale (HADS) were used for determine depression and anxiety in these patients.
Results: 80.3% ulcerative colitis and 19.7% Crohn's disease was observed in patients. The mean of total anxiety score in the group with Crohn's disease was higher than ulcerative colitis but there was no significant difference. Total score of depression was similar and not significant in both groups. There was a significant statistical relationship between marital status and anxiety in patients with ulcerative colitis only (P<0.05). As borderline and suspicious status of the patient in married patients is 42.4% and in single patients is 33.3%. Abnormal anxiety state was 31.8% in married patients and not seen in single patients. A positive and significant correlation was seen between total anxiety scale and total depression scale in patients with ulcerative colitis (correlation index: 0.657, P<0.0001) and in patients with Crohn's disease (correlation index: 0.644, P<0.001). Therefore in these patients, if depression increases, anxiety was also increasd. Anxiety observed in 29.8% and 26.1% of ulcerative colitis and Crohn's disease, respectively. Depression disorders observed in 18.1% and 8.7% of ulcerative colitis and Crohn's disease, respectively.
Conclusion: This study showed that the level of anxiety and depression in patients with inflammatory disease is very high. |
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Keywords: Inflammatory Bowel Diseases [MeSH], Anxiety Disorders [MeSH], Depression [MeSH]
Article ID: Vol24-10 |
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Full-Text [PDF 511 kb]
(9808 Downloads)
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Type of Study: Original Articles |
Subject:
Psychiatry
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| References |
1. Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterology. 2004 May; 126(6): 1504-17. DOI: 10.1053/j.gastro.2004.01.063 [ DOI] [ PubMed] 2. Pittet V, Juillerat P, Mottet C, Felley C, Ballabeni P, Burnand B, et al. Cohort profile: the Swiss Inflammatory Bowel Disease Cohort Study (SIBDCS). Int J Epidemiol. 2009 Aug; 38(4): 922-31. DOI: 10.1093/ije/dyn180 [ DOI] [ PubMed] 3. Burisch J, Jess T, Martinato M, Lakatos PL; ECCO -EpiCom. The burden of inflammatory bowel disease in Europe. J Crohns Colitis. 2013 May; 7(4): 322-37. DOI: 10.1016/j.crohns.2013.01.010 [ DOI] [ PubMed] 4. Mayer EA, Craske M, Naliboff BD. Depression, anxiety, and the gastrointestinal system. J Clin Psychiatry. 2001; 62 (Suppl 8): 28-36. [ PubMed] 5. Qualter P, Rouncefield-Swales A, Bray L, Blake L, Allen S, Probert C, et al. Depression, anxiety, and loneliness among adolescents and young adults with IBD in the UK: the role of disease severity, age of onset, and embarrassment of the condition. Qual Life Res. 2021 Feb; 30(2): 497-506. DOI: 10.1007/s11136-020-02653-9 [ DOI] [ PubMed] 6. Sidebottom AM, Rodriguez TG, Karpin JE, Rubin DT. Clinical and Translational Considerations for Understanding Depression and Anxiety in Patients with Inflammatory Bowel Disease. Gastroenterol Res Pract. 2021 Mar; 2021: 6689443. DOI: 10.1155/2021/6689443 [ DOI] [ PubMed] 7. Porcelli P, Affatati V, Bellomo A, De Carne M, Todarello O, Taylor GJ. Alexithymia and psychopathology in patients with psychiatric and functional gastrointestinal disorders. Psychother Psychosom. 2004 Mar-Apr; 73(2): 84-91. DOI: 10.1159/000075539 [ DOI] [ PubMed] 8. Sceats LA, Dehghan MS, Rumer KK, Trickey A, Morris AM, Kin C. Surgery, stomas, and anxiety and depression in inflammatory bowel disease: a retrospective cohort analysis of privately insured patients. Colorectal Dis. 2020 May; 22(5): 544-53. doi: 10.1111/codi.14905 [ DOI] [ PubMed] 9. Choi K, Chun J, Han K, Park S, Soh H, Kim J, et al. Risk of Anxiety and Depression in Patients with Inflammatory Bowel Disease: A Nationwide, Population-Based Study. J Clin Med. 2019 May; 8(5): 654. DOI: 10.3390/jcm8050654 [ DOI] [ PubMed] 10. Drossmana DA, Creedb FH, Oldenc KW, Svedlundd J, Tonere BB, Whiteheadf WE. Psychosocial aspects of the functional gastrointestinal disorders. Gut. 1999; 45(Suppl II): II25–II30. [ View at Publisher] 11. Kaviani H, Seyfourian H, Sharifi V, Ebrahimkhani N. [Reliability and validity of Anxiety and Depression Hospital Scales (HADS): Iranian patients with anxiety and depression disorders]. Tehran Univ Med J. 2009; 67(5): 379-85. [Article in Persian] [ View at Publisher] 12. Goodhand JR, Wahed M, Mawdsley JE, Farmer AD, Aziz Q, Rampton DS. Mood disorders in inflammatory bowel disease: relation to diagnosis, disease activity, perceived stress, and other factors. Inflamm Bowel Dis. 2012 Dec; 18(12): 2301-9. DOI: 10.1002/ibd.22916 [ DOI] [ PubMed] 13. Byrne G, Rosenfeld G, Leung Y, Qian H, Raudzus J, Nunez C, et al. Prevalence of Anxiety and Depression in Patients with Inflammatory Bowel Disease. Can J Gastroenterol Hepatol. 2017; 2017: 6496727. DOI: 10.1155/2017/6496727 [ DOI] [ PubMed] 14. Fakheri H, Zarghami M, Shahsavari M, Bari Z, Yazdani J. [Evaluation of the Correlation between Anxiety, Depression and Personality Traits with Immunologic Markers (ANCAs) in Ulcerative Colitis]. Govaresh. 2011; 16(2): 91-97. [Article in Persian] [ View at Publisher] 15. Mikocka-Walus A, Pittet V, Rossel JB, von Känel R; Swiss IBD Cohort Study Group. Symptoms of Depression and Anxiety Are Independently Associated With Clinical Recurrence of Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2016 Jun; 14(6): 829-35.e1. DOI: 10.1016/j.cgh.2015.12.045 [ DOI] [ PubMed] |
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Kashani L, Derakhshanpour F, Eliasi M, Shahini N, Hasheminasab S M. Evaluation of Anxiety and Depression Disorders in Patients with Inflammatory Bowel Disease in Golestan Province, North of Iran. J Gorgan Univ Med Sci 2022; 24 (1) :74-79 URL: http://goums.ac.ir/journal/article-1-3879-en.html
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