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Effect of Six Weeks of High Intensity Interval Training with Nano-curcumin Supplementation on Serum Levels of Hepatic Enzymes in Overweight Female Students: A Clinical Trial Study
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Somaye Fakhri1    , Fatemeh Fakhri1 , Saeed Shakeryan * 2, Aliakbar Alizaded3 |
1- M.A in Sport Science, Department of Exercise Physiology, Faculty of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
2- Associate Professor, Department of Exercise Physiology, Faculty of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran. , s.shakeryan@scu.ac.ir
3- Assistant Professor, Department of Exercise Physiology, Faculty of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran. |
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Abstract: (4414 Views) |
Background and Objective: Physical activity and the use of herbal supplements can affect liver enzymes. Nano-curcumin is an effective ingredient (deferulovl methane) in turmeric with antioxidant, antibacterial, antifungal, antiviral, anti-inflammatory and anti-proliferative properties and can play an important role in preventing liver fibrosis. This study was performed to determine the effect of 6 weeks of high intensity interval training (HIIT) with Nano-curcumin supplementation on liver enzyme levels in overweight female students.
Methods: This clinical trial study was performed on 48 overweight female students of Shahid Chamran University of Ahvaz, Iran with an average age of 21.7±1.32 years and a BMI equals 27.8±2.46kg/m2 during 2018. Participants were randomly divided into 4 groups: control, Nano-curcumin supplementation (One 80 mg capsule daily), training and training combined with nano-curcumin supplementation (one 80 mg capsule daily). Training groups performed an exercise protocol of HIIT training with maximum heart rate for 6 weeks (three sessions per week). Blood samples were obtained to liver enzymes measurement (ALT, AST and ALP) before and after the intervention period.
Results: Performing six weeks of high intensity interval training along with taking nano-curcumin supplemen led to a significant reduction in serum level of AST and ALT compared to control group (P<0.05). In the supplement-training group, a significant decrease was observed in serum levels of ALT and AST compared to pre-test (P<0.05). But no statistically significant changes were observed in ALP serum level.
Conclusion: It seems taking nano-curcumin supplement along with high intensity interval training have a favorable effects on improving some of the liver characteristics of overweight female students. |
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Keywords: High Intensity Interval Training [MeSH], Curcumin [MeSH], Liver [MeSH], Overweight [MeSH], Enzymes [MeSH]
Article ID: Vol23-35 |
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Full-Text [PDF 847 kb]
(15772 Downloads)
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Type of Study: Original Articles |
Subject:
Exercise Physiology
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Fakhri S, Fakhri F, Shakeryan S, Alizaded A. Effect of Six Weeks of High Intensity Interval Training with Nano-curcumin Supplementation on Serum Levels of Hepatic Enzymes in Overweight Female Students: A Clinical Trial Study. J Gorgan Univ Med Sci 2021; 23 (3) :16-23 URL: http://goums.ac.ir/journal/article-1-3805-en.html
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