Frequency of congenital heart disease using ecocardiography in patients with extra-cardiac anomalies in gorgan peadiatric center, north of Iran (2012-17)
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Mohsen Ebrahimi1 , Hassan Esmaeili * 2, Ahmad Mohammadipour3 , Fatemeh Rostami4 |
1- Assistant Professor of Pediatric Allergy and Immunology, Neonatal and Children's Health Research Center, Department of Pediatrics, Taleghani Medical Educational Center, Golestan University of Medical Sciences, Gorgan, Iran. 2- Assistant Professor of Pediatric Cardiology, Gorgan Congenital Malformations Research Center, Department of Pediatrics, Taleghani Medical Educational Center, Golestan University of Medical Sciences, Gorgan, Iran. , he_md1972@yahoo.com 3- Assistant Professor of Pediatric Surgery, Department of Pediatrics, School of Medicine, Taleghani Medical Educational Center, Golestan University of Medical Sciences, Gorgan, Iran. 4- General Physician, Neonatal and Children's Health Research Center, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran. |
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Abstract: (6321 Views) |
Background and Objective: Congenital anomalies are one of the major causes of neonatal mortality. Congenital heart disease (CHD) is the most common birth defect world wide, and recent studies about CHD have reported congenital heart disease approximately is about one percent of all live births. This study was done to determine the frequency of congenital heart disease using ecocardiography in patients with extra-cardiac anomalies in Gorgan peadiatric center in north of Iran.
Methods: In this descriptive study, 55 girls, 84 boys a total of 139 patients were in the age range of birth to 12 years of age whom have referred to Taleghani Teaching and Medical Center in Gorgan during 2012-17. 139 cases of congenital heart disorders with echocardiographic report sheet in their medical record were evaluated. Information of patients including age, sex, ethnicity, type of extra-cardiac, anomalies, cardiac anomalies (simple, complex and ductal anomalies), cardiac murmur status, and clinical symptoms were extracted from their medical records.
Results: From of total of echocardiography, 139 patients (88.5%) were affected by congenital heart disease. The anomalies were included of 88 cases (56.05%), 48 cases (31.21%), 2 cases (1.27%) simple, complex anomaly and ductal dependent anomaly respectively. The other disorders accompanied with congenital heart diseases were 17 cases (12.2%) with cleft palate, 4 cases (2.9%) with congenital diaphragmatic hernia, 8 cases (5.8%) with closed anus, 52 cases (37.4%) with Down syndrome, 4 cases (2.9%) with Turner syndrome, 4 cases (2.9%) with ileum atresia, 11 cases (7.9%) with Esophageal atresia, 7 cases (5%) with Hirschsprung's disease, 6 cases (4.3%) with urogenital anomalies and 26 cases (18.7%) with other extra-cardiac abnormalities.
Conclusion: Down syndrome and cleft palate are among the highest prevalant anomalies with congenital heart diseases. |
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Keywords: Congenital Heart Disease [MeSH], Congenital Disorders [MeSH], Echocardiography [MeSH] Article ID: Vol22-64 |
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Type of Study: Original Articles |
Subject:
Pediatric
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1. Fahed AC, Gelb BD, Seidman JG, Seidman CE. Genetics of congenital heart disease: the glass half empty. Circ Res. 2013 Feb; 112(4): 707-20. DOI: 10.1161/CIRCRESAHA.112.300853 [ DOI] [ PubMed] 2. Chelo D, Nguefack F, Menanga AP, Ngo Um S, Gody JC, Tatah SA, et al. Spectrum of heart diseases in children: An echocardiographic study of 1,666 subjects in a pediatric hospital, Yaounde, Cameroon. Cardiovasc Diagn Ther. 2016 Feb; 6(1): 10-19. DOI: 10.3978/j.issn.2223-3652.2015.11.04 [ DOI] [ PubMed] 3. Kouame BD, N'guetta-Brou IA, Yapo Kouame GS, Sounkere M, Koffi M, Yaokreh JB, et al. Epidemiology of congenital abnormalities in West Africa: Results of a descriptive study in teaching hospitals in Abidjan: Cote D'ivoire. Afr J Paediatr Surg. 2015 Jan-Mar; 12(1): 51-55. DOI: 10.4103/0189-6725.150983 [ DOI] [ PubMed] 4. Dolk H, Loane M, Garne E, European Surveillance of Congenital Anomalies (EUROCAT). Congenital heart defects in Europe: prevalence and perinatal mortality, 2000 to 2005. Circulation. 2011 Mar; 123(8): 841-49. DOI: 10.1161/CIRCULATIONAHA.110.958405 [ DOI] [ PubMed] 5. Qazi M, Saqib N. Spectrum of congenital heart disease in neonates in a tertiary care centre of Northern India. Int J Contemp Pediatr. 2018 Jul; 5(4): 1505-8. DOI: 10.18203/2349-3291.ijcp20182554 [ DOI] [ PubMed] 6. Krasuski R, Bashore TM. Congenital Heart Disease Epidemiology in the United States. Circulation. 2016 Jul; 134(2): 110-13. DOI: 10.1161/CIRCULATIONAHA.116.023370 [ DOI] [ PubMed] 7. Meberg A. Congenital heart defects through 30 years. Open J Pediatr. 2012; 2(3): 219-27. DOI: 10.4236/ojped.2012.23035 [ Article] [ DOI] 8. van der Linde D, Konings EE, Slager MA, Witsenburg M, Helbing WA, Takkenberg JJ, et al. Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis. J Am Coll Cardiol. 2011 Nov; 58(21): 2241-47. DOI: 10.1016/j.jacc.2011.08.025 [ DOI] [ PubMed] 9. Blue GM, Krik EP, Sholler GF, Harvey RP, Winlaw DS. Congenital heart disease: current knowledge about causes and inheritance. Med J Aust. 2012; 197(3): 155-59. [ Article] 10. Egbe A, Lee S, Ho D, Uppu S, Srivastava S. Prevalence of congenital anomalies in newborns with congenital heart disease diagnosis. Ann Pediatr Cardiol. 2014 May; 7(2): 86-91. DOI: 10.4103/0974-2069.132474 [ DOI] [ PubMed] 11. Nikyar B, Sedehi M, Qorbani M, Nikyar A, Golalipour MJ. Ethnical variations in the incidence of congenital heart defects in Gorgan, Northern Iran: A single-center study. J Tehran Heart Cent. 2014 Jan; 9(1): 9-14. [ PubMed] 12. Tomek V, Marek J, Jicínská H, Skovránek J. Fetal cardiology in the Czech republic: Current management of prenatally diagnosed congenital heart diseases and arrhythmias. Physiol Res. 2009; 58 (Suppl 2): S159-66. [ PubMed] 13. Khairy P, Ionescu-Ittu R, Mackie AS, Abrahamowicz M, Pilote L, Marelli AJ. Changing mortality in congenital heart disease. J Am Coll Cardiol. 2010 Sep; 56(14): 1149-57. DOI: 10.1016/j.jacc.2010.03.085 [ Article] [ DOI] 14. Song MS, Hu A, Dyamenahalli U, Chitayat D, Winsor EJT, Ryan G, et al. Extracardiaclesions and chromosomal abnormalities associated with major fetal heart defects: comparison of intrauterine, postnatal and postmortem diagnoses. Ultrasound Obstet Gynecol. 2009 May; 33(5): 552-59. DOI: 10.1002/uog.6309 [ DOI] [ PubMed] 15. Majeed-Saidan MA, Atiyah M, Ammari AN, AlHashem AM, Rakaf MS, Shoukri MM, et al. Patterns, prevalence, riskfactors, and survival of newborns with congenital heart defects in a Saudi population: a three-year, cohort case-control study. Journal of Congenital Cardiology. 2019; 3: 2. DOI: 10.1186/s40949-019-0023-8 [ Article] [ DOI] 16. Dilber D, Malcic I. Spectrum of congenital heart defects in Croatia. Eur J Pediatr. 2010 May; 169(5): 543-50. DOI: 10.1007/s00431-009-1064-3 [ Article] [ DOI] 17. Khalilian MR, Emami Moghadam A, Ebrahimi M, Norouzi AR, Alaei F, Badvi N. Evaluating the overt extracardiac malformations in children with congenital heart disease in Khuzestan Province. Caspian J Pediatrics. 2017; 3(1): 201-4. DOI: 10.22088/acadpub.BUMS.3.1.201 [ View at Publisher] [ DOI] 18. Egbe A, Uppu S, Lee S, Deborah H, Srivastava S. Associated extracardiac malformations in the congenital heart disease population: current estimates and temporal variation in prevalence. J Am Coll Cardiol. 2014 Apr; 63(12): A599. DOI: 10.1016/S0735-1097(14)60599-4 [ Article] [ DOI] 19. Amorim LF, Pires CA, Lana AM, Campos AS, Aguiar RA, Tiburcio JD, et al. Presentation of congenital heart disease diagnosed at birth: analysis of 29,770 newborn infants. J Pediatr (Rio J). 2008 Jan-Feb; 84(1): 83-90. DOI: 10.2223/JPED.1747 [ DOI] [ PubMed] 20. Karande S, Patil V, Kher A, Muranjan M. Extracardiac birth defects in children with congenital heart defects. Indian Pediatr. 2014 May; 51(5): 389-91. DOI: 10.1007/s13312-014-0415-y [ DOI] [ PubMed]
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Ebrahimi M, Esmaeili H, Mohammadipour A, Rostami F. Frequency of congenital heart disease using ecocardiography in patients with extra-cardiac anomalies in gorgan peadiatric center, north of Iran (2012-17). J Gorgan Univ Med Sci 2020; 22 (4) :132-137 URL: http://goums.ac.ir/journal/article-1-3689-en.html
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