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:: Volume 19, Issue 1 (3-2017) ::
J Gorgan Univ Med Sci 2017, 19(1): 47-53 Back to browse issues page
The association of dietary β-carotene and β-cryptoxanthin with the incidence of insulin resistance in adults: Tehran Lipid and Glucose Study
S Khalili Moghadam1 , Z Bahadoran2 , P Mirmiran * 3, F Azizi4
1- M.Sc Student of Nutrition, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Science and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Ph.D in Nutrition, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Science and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3- Professor, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Science and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran , mirmiran@endnocrine.ac.ir
4- Professor, Endocrine Research Center, Research Institute for Endocrine Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:   (10263 Views)

Background and Objective: Dietary intake of β-carotene and β-cryptoxanthin may be associated with reduce the risk of insulin resistance, due to their antioxidant properties. The aim of this study was to determine the relation between dietary intake of β-carotene and β-cryptoxanthin and the risk of insulin resistance in adults.

Methods: In this prospective cohort study, 938 (421 men and 517 women), aged between 19 to 82 years were selected from among participants of the Tehran Lipid and Glucose Study in Iran. Dietary intake of β-carotene and β-cryptoxanthin were determined using a valid and reliable food frequency questionnaire. Fasting serum glucose and insulin were measured at base line and again after a 3-year of follow up. Logistic regression models were used to estimate the occurrence of insulin resistance across tetiles of β-carotene and β-cryptoxanthin with adjustment for potential confounding variables.

Results: The mean age of participants was 40.7±12.1 years. β-carotene was inversely associated with insulin resistance after adjustment for confounder variables (95% CI= 0.25–0.72, OR= 0.42, P-value for trend=0.01). Also, an inverse association was found between dietary intake of β-cryptoxanthin and insulin resistance risk (95% CI= 0.30-0.84, OR= 0.51, P-value for trend=0.01).

Conclusion: There was inverse association between dietary intake of β-carotene and β-cryptoxanthin and risk of insulin resistance in adults.
Keywords: Insulin, Insulin resistance index, β-carotene, β-cryptoxanthin
Full-Text [PDF 250 kb] [English Abstract]   (11174 Downloads) |   |   Abstract (HTML)  (1077 Views)  
Type of Study: Original Articles | Subject: Internal Medicine
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Khalili Moghadam S, Bahadoran Z, Mirmiran P, Azizi F. The association of dietary β-carotene and β-cryptoxanthin with the incidence of insulin resistance in adults: Tehran Lipid and Glucose Study . J Gorgan Univ Med Sci 2017; 19 (1) :47-53
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Volume 19, Issue 1 (3-2017) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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