Fungus paranasal sinusitis in non- immunocompromised patients in Tehran, Iran (2006-07)
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Nowrozi H (PhD) * 1, Alavi Sh (Pharm D)2 , Kazemi A (MSc)3 , Razmpa E (MD)4 , Emami M (PhD)5 , Oshaghi M (PhD)6 ![](./files/0allsites/images/pubmed20.png) |
1- Assistant Professor, Department of Medical Mycology, Faculty of Allied Medicine, Tehran University of Medical Sciences, Tehran, Iran , nowrozi_h@tums.ac.ir 2- Doctor of Pharmacy, Shahriyar Hospital, Shahriyar, Iran 3- Academic Instructor, Department of Pharmacology, Islamic Azad University, Gomishan Branch, Gomishan, Iran 4- Associate Professor, Department of ENT, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran 5- Professor, Department of Medical Mycology, Faculty of Hygiene, Tehran University of Medical Sciences, Tehran, Iran 6- Assistant Professor, Department of Medical Bacteriology, Faculty of Allied Medicine, Tehran University of Medical Sciences, Tehran, Iran |
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Abstract: (18204 Views) |
Background and Objective: Incidence of fungal infections particularly fungal sinusitis is increasing in Iran and identification of causative agents is essential for its control and treatment. This study was carried out to determine the fungus paranasal sinusitis in non- immunocompromised patients in Tehran, Iran.
Materials and Methods: This cross – sectional study was done on 108 patients (73 males, 35 females) with chronic sinusitis ranged from 9 to 68 years, admitted to Amir Alam and Emam Khomeini hospitals in Tehran, Iran during 2006-07. Sinusitis in patients confirmed by radiologic images. Complementry information were obtained using questionnaires which including gender, job, presence of disposing disease diabetes and consumption immunocompromised drugs. Sinus samples were collected by washing and biopsy were carried out by two methods of fenestration and Cald-wel luc operations. Subsequently they were cultured on Sabouraud dextrose agar (SDA), SDA+chloramphenicol and blood agar (BA) media at 30°C and 37°C. Direct examination and fixative sample for histhologic evaluation was done and for colonies confirmation the slide culture method also was used.
Results: 8 cases (7.4 %) were positive for fungal sinusitis with following sub type: 6 cases (Alternaria Spp), 1 case (Paecilomyces) and 1 case (Aspergillus flavus). The most fungal sinusitis (5 cases) were observed in 30-39 years patients.
Conclusion: Considering the prevalence of 7.4 % fungal sinusitis and isolation of paecilomyces which is a rare subtype complematry investigation is recommended, in the field of research. |
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Keywords: Fungal sinusitis, Paranasal sinuses, Fungal agents |
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[English Abstract]
(15996 Downloads)
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Type of Study: Short Communication |
Subject:
Mycology
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