Showing 9 results for Resistance Training
Jamshid Banaii Broojeni, Saeed Keshavarz, Iman Zakavi,
Volume 7, Issue 1 (3-2019)
Abstract
Background and objectives: The purpose of the present study was to examine the effect of a progressive resistance-training program beside an energy deficit diet on body Composition, insulin resistance and plasma adiponectin levels in overweight adult men.
Methods: Twenty-five overweight men (age =32.1 ± 4.3 years, BMI =28.9 ± 1.3 kg.m-2) were randomly assigned into one of the two groups: resistance training+ diet (RD, n =15); and diet only (DO, n =12). Both groups undertook a 12-week weight loss program using a moderate isocaloric energy deficit.
Results: After 12 weeks intervention, there was equivalent significant weight loss for both groups (p <0.01). Total and abdominal fat mass, fasting insulin concentration and HOMA-IR score were decreased in both groups (p <0.01). All previously mentioned variables except fasting insulin levels were more significantly reduced in RD compared to DO group. There was a significant decrease in lean body tissue only in DO (p <0.01) group. We did not find any significant changes in plasma adiponectin concentration of the experimental groups. Reduction in insulin resistance had a significant positive correlation with abdominal and total fat loss (p < 0.05) and a negative correlation with lean mass loss (p < 0.05).
Conclusion: Adding a progressive resistance-training program to an energy deficit diet, without any change on magnitude of weight loss could prevent the loss of lean body mass and improve the reduction of total and abdominal fat mass and insulin resistance. Moreover, the change in body composition and insulin resistance was accompanied with no significant change in plasma adiponectin.
Somaye Pouranfar, Mohammad Ali Azarbayjani, Bahram Abedi,
Volume 8, Issue 4 (12-2020)
Abstract
Background and Objective: Reports indicate that over 60% of people with diabetes die from cardiovascular diseases. The present study was conducted to investigate the interactive effects of resistance training and genistein consumption on the serum levels of vascular cell adhesion molecule 1 (VCAM-1), intercellular adhesion molecule 1 (ICAM-1) and C-Reactive Protein (CRP) in diabetic rats with streptozotocin.
Material And Methods: In this experimental study, 40 diabetic rats were selected and divided into 5 groups of 8 subjects, including: (1) control, (2) sham (dimethyl sulfoxide), (3) resistance training (4), genistein consumption, and (5) resistance training and genistein consumption. Rats in groups 3 and 5 received 8 weeks of resistance training, 3 sessions per week, with 30 to 100% body weight, and rats in groups 4 and 5 received 30 mg/kg of peritoneal genistein per day. Data were analyzed using independent sample t-test and two-way ANOVA in SPSS software (p≤0.05).
Results: Genistein consumption has a significant effect on reduced serum levels of VCAM and ICAM in diabetic rats (p≤0.05). Eight weeks of resistance training has a significant effect on reduced serum levels of ICAM and CRP in diabetic rats (p≤0.05). Resistance training and genistein consumption have interactive effects on reduced serum levels of VCAM and CRP in diabetic rats (p≤0.05).
Conclusion: Resistance training and genistein consumption simultaneously appear to reduce the risk of atherosclerosis in diabetic rats.
Abdossaleh Zar, Fatemeh Ahmadi,
Volume 9, Issue 2 (5-2021)
Abstract
Background and Objective: Effects of resistance training and herbal supplements on cardiac signaling pathways are sparsely reported in the literature. This study aimed to evaluate the CITED4 gene expression in the cardiac muscle of male rats as a result of resistance exercise and spirulina supplementation.
Material and Methods: Thirty-two rats (male - Sprague Dally) were grouped into 4 groups (1. resistance training: RE, 2. spirulina + resistance training: SP +RE, 3. spirulina platensis: SP, 4. control: Co, n = 8). The training program was performed for healthy training groups 5 sessions per week for 8 weeks. Supplementation included 200 mg/kg/ day of Spirulina for the supplement groups. Real-time PCR was used to measure gene expression. We used of Two-way ANOVA in SPSS (p<0.05).
Results: In comparison with the control group, we observed a significant increase in CITED4 gene expression in RE (P= 0.001) and RE+SP (P= 0.001) groups. Also, there was a significant difference in CEBP gene expression between CO with RE (P= 0.001), SP (P= 0.034), RE+SP (P= 0.001) groups.
Conclusion: Spirulina supplementation alone has no effect on the signaling pathway of cardiac hypertrophy. However, if used concomitantly with resistance training, it can affect the signal pathway of cardiac hypertrophy.
Samaneh Jadidi , Seyed Mohsen Avandi, Ali Khaleghian ,
Volume 11, Issue 1 (7-2023)
Abstract
Samaneh Jadidi,
Seyed Mohsen Avandi 
,
Ali Khaleghian
Background: Obesity is one of the most serious health problems associated with inflammation. It has been found that functional and resistance physical activities improve obesity and inflammation. The aim of this study was to investigate the effect High-intensity Functional training (HIFT) and Circuit resistance training (CRT) on serum levels of the pro-inflammatory factor interferon gamma (IFN-γ) in obese women.
Methods: Thirty-six obese women of Semnan city (age: 32.66 ± 3.91, weight: 86.97± 9.08 and BMI> 30) were selected and divided into three groups of HIIF (n =12), CRT (n = 12) and control (n = 12) were divided. HIIF was performed in the form of cross-fit exercises and Circuit exercises in the form of weight training for 6 weeks. Finally, the IFN-γ was measured using the Human IFN-g Elisa kit 96t-zellbio. To examine the data, one-way analysis of variance and dependent t-test at the level of p≤0.05 were used and all calculations were performed using SPSS software version 24.
Results: The results showed that there was no significant change in IFN-γ level in training groups compared to before training (P>0.05). Also, the results between groups did not show a significant difference in serum IFN-γ between HIIF and CRT (P>0.05).
Conclusion: Therefore, it seems that of exercise does not affect the dependent variable of serum interferon gamma levels.
Farah Nameni, Sviz Khalili Shavarini,
Volume 11, Issue 2 (10-2023)
Abstract
Background: Recently, the role of sports training and medicinal plants in the expression of genes has been considered to prevent the progression of diseases. The purpose of this research was to investigate the role of weight training and oleander extract on interferon regulatory factor 8 (IRF8) and cathepsin S (CTSS) gene expression in the soleus muscle of Alzheimer's disease (AD) model mice.
Methods: Fifty-five male Wistar rats were randomly divided into 5 groups: healthy control group, AD control group, AD resistance training group, AD group with the supplement of Melilotus officinalis, and AD resistance training group + Melilotus officinalis supplement. Trimethyltin-induced AD was induced. In the resistance training protocol, a weight was attached to the tail of the rats, and they had to lift this weight on a ladder with 26 steps. Melilotus officinalis was injected intraperitoneally as a supplement for 6 weeks with a dose of 300 mmol/kg. Seventy-two hours after the last training session, the rats were anesthetized, and the hippocampal tissue was immediately extracted, frozen, and analyzed. A two-way analysis of variance was used to estimate the differences between groups in control and experimental AD mice.
Results: There was a significant increase in the expression level of interferon-regulating factor 8 and cathepsin S genes in the AD group compared to the control group. The results of Bonferroni's post-hoc test showed that in the AD group + resistance training + Melilotus officinalis, a significant decrease was observed compared to the AD group (P≤0.05).
Conclusion: Resistance training and the Melilotus officinalis extract with antioxidant mechanisms can affect CTSS and IRF8 gene expression.
Yalda Sadeghi, Ali Khajehlandi, Mohabat Salehi, Amin Mohammadi,
Volume 11, Issue 4 (12-2023)
Abstract
Background: Obesity carries great risks related to health, such as the development and progression of chronic inflammation and obvious metabolic disorders. This study aimed to examine the effect of eight weeks of moderate-intensity resistance training with garlic supplementation on the lipid profile in overweight women.
Methods: The present research was a semi-experimental study and the participants were 60 overweight women from Gachsaran City with (body mass index: 28/45±6/72) who were randomly divided into four groups (n = 15): supplemental exercise, placebo exercise, garlic supplemental, and placebo. Two training groups performed moderate-intensity resistance training for eight weeks and three sessions per week. One day before the start of training and 48 hours after the last training session, blood samples were collected to measure total cholesterol (TC), triglyceride (TG), LDL-C, and HDL-C variables. Data were analyzed by one-way ANOVA and LSD post-hoc test.
Results: Findings showed that there is a significant decrease in the serum levels of TC, TG, and LDL-C and a significant increase in HDL-C (P<0.05) serum levels in three groups of supplemental exercise, placebo exercise, and garlic supplemental compared to the placebo group.
Conclusion: Moderate-intensity resistance training with and without consuming garlic improves overweight women's lipid profile, and when exercise is accompanied by consuming garlic, the amount of these changes and improving the lipid profile is greater.
Hossein Eidizadeh, Seyed Mohsen Avandi, Abdosalleh Zar, Hamid Reza Sadeghipour,
Volume 12, Issue 1 (10-2024)
Abstract
Background: Resistance training and protein supplementation are known to increase protein synthesis and hypertrophy, primarily through the activation of the mTORC1 signaling pathway. However, mTORC1 activation in the kidneys can potentially lead to kidney disease. This study investigates the effects of eight weeks of resistance training combined with Spirulina platensis supplementation on the RAGs/Rheb/mTOR/S6K pathway in male rat kidneys.
Methods: In this study, 32 male Sprague-Dawley rats were divided into four groups: control (Co; n = 8), Spirulina platensis (SP; n = 8), resistance training (RE; n = 8), and Spirulina platensis + resistance training (SP+RE; n = 8). The resistance training group engaged in five sessions per week over eight weeks. Spirulina was administered at a dosage of 200 mg/kg/day to the supplement and SP+RE groups. Gene expression was analyzed using real-time PCR following the last training session.
Results: The mTOR gene expression significantly increased in the SP group (p = 0.01), while no significant changes were observed in the RE and SP+RE groups. Rheb gene expression did not show significant changes across any groups. Significant changes were noted in the RAGs gene in the SP group (p = 0.001), RE group (p = 0.047), and SP+RE group (p = 0.025). The S6K gene showed significant changes in the SP group (p = 0.01) but not in the other groups.
Conclusion: Spirulina supplementation may activate the mTORC1 signaling pathway in the kidneys, potentially contributing to kidney disease progression. However, combined resistance training and Spirulina supplementation did not show changes in mTORC1 expression, suggesting that this combination might prevent further kidney tissue damage in athletes.
Azar Mohammadi, Abdolhossein Taheri Kalani, Mahnaz Omidi,
Volume 12, Issue 1 (10-2024)
Abstract
Background: When metabolic demands increase due to an obesity-induced high-fat diet (HFD), mitochondrial function is impaired, production can increase, and oxidative stress occurs. This type of stress has been shown to play a key role in various pathological conditions such as heart disease, hypertension, diabetes, chronic kidney disease, and cancers. This study aims to evaluate the impact of HFD and resistance training (RT) on oxidative stress biomarkers and cardiac health in rats.
Methods: In this experimental study, 21 male Wistar rats (weighing 200-300 g) were randomly and equally assigned into the following groups: control (CTRL), HFD, and HFD+ RT. Animals in the HFD groups received a high-fat diet for 23 weeks. During the treatments, rats in the HFD+ RT group, besides receiving a high-fat diet, performed the progressive RT protocol three times per week with 30- 100% of their body mass in the last eight weeks. At the end of the treatments, superoxide dismutase (SOD), glutathione peroxidase (GPX), total antioxidant capacity (TAC), and malondialdehyde (MDA) levels in cardiac tissue were measured by colorimetric method. The data were analyzed by one-way analysis of variance (ANOVA) and Tukey’s post hoc test at a significant level of P<0.05.
Results: HFD did not alter levels of SOD, GPX, TAC, or MDA in cardiac tissue. Cardiac SOD (P=0.021), GPX (P=0.024), and TAC (P=0.041) levels in the HFD+ RT increased significantly compared to the HFD group, but there was no significant difference in cardiac MDA levels between the three groups (P=0.438).
Conclusion: RT seems to improve cardiac tissue oxidative stress adaptations in an animal model fed with an HFD.
Sara Valikhani, Seyed Mohsen Avandi, Mehdi Hedayati ,
Volume 12, Issue 4 (4-2024)
Abstract
Background: Circuit resistance training, beneficial to overweight individuals, combines aerobic and resistance exercises. This study aimed to investigate the effect of multi-joint circuit resistance training on serum adiponectin levels and lipid profiles in overweight women.
Methods: Thirty sedentary overweight women (mean age of 34.48±4.304 years, mean weight of 81.17±9.137 kg, and mean BMI of 30.17±2.13 kg/m2) were randomly divided into two groups: circuit resistance training (n=15) and a control group (n=15). The experimental group trained at 65–85% of maximum heart rate for eight weeks, with three sessions per week (24 sessions total). The control group did not engage in regular exercise. Serum adiponectin levels and lipid profiles were assessed before and after the intervention. Data were analyzed using paired sample t-tests and dependent t-tests at a significance level of P-value≤0.05.
Results: The results showed that adiponectin levels (P-value=0.001) and cholesterol levels (P-value=0.015) increased in the circuit training group, while LDL levels decreased (P-value=0.031). HDL levels increased but were not statistically significant (P-value=0.100). These variables did not change in the control group.
Conclusion: Finding ways to improve the state of adipokines is of vital importance for these patients. According to the results, circuit resistance training may be an effective method for addressing dyslipidemia and increasing adiponectin levels in overweight women.
