Maryam Kazemipoor, Fatemeh Owlia, Mehri Esfandyar, Ali Dehghani, Hossein Fallahzadeh, Amir Houshang Mehrparvar, Mohammad Javad Zare Sakhvidi, Masoud Mirzaei,
Volume 7, Issue 2 (7-2019)
Abstract
Backgrounds and Objectives: Afew large population-based studies have been conducted on the prevalence of oral mucosal lesions in relation to fertility status in the Iranian population. The aim of study was determine the prevalence of oral mucosal lesions in relation to fertility status in women participants of Shahedieh cohort study.
Materials and Methods: A descriptive cross-sectional study was conducted on 4935 women who participated in the Shahedieh cohort study. The age range of participants was 35-71 years with a mean age of 47.12 years. The prevalence of oral mucosal lesions considering fertility variables including pregnancy, number of pregnancy, oophorectomy, tubectomy, hysterectomy, infertility, menopause, normal menopause, and abortion, application of infertility and oral contraceptive drugs and hormone replacement therapy were recorded.
Results: The total prevalence of oral mucosal lesions in the studied women were 3.8%. The most commonly affected age group was 40-49 years, followed by 30-39, 50-59 and 60-71 years, respectively. Considering the fertility variables, only menopause (P=0.047) and normal menopause (P=0.024) significantly related to the prevalence of oral mucosal lesions.
Conclusions: The findings of the present study provide information on the prevalence of the oral mucosal lesions considering fertility status in a large population-based study in Iran. With due attention to the higher prevalence of oral mucosal lesions in menopause women, an improved comprehension of oral manifestations at menopause and preventive and treatment approaches during this period should be programmed with health care services to meet the needs of patients deservingly.
Mohammad-Sadegh Alemrajabi, Maryam-Sadat Sadrzadeh-Afshar, Mahdi Dastorani, Meysam Barjestehnia,
Volume 10, Issue 1 (3-2022)
Abstract
Background and objectives: Recurrent Aphthous Stomatitis (RAS) is a common disease of the nonkeratinized oral mucosa characterized by painful ulcerations and inflammation, causing difficulty in eating, swallowing, and speaking. Symptomatic treatment is considered for this disease due to the ambiguity of the exact etiology. The beneficial therapeutic effects of Persica and Propolis mouthwashes led us to the objective of studying therapeutic potentials of these herbal mouthwashes.
Material and Methods: The present double-blind clinical trial was conducted on 40 patients with minor aphthous ulcers and no systemic disease, who were divided into two groups of 20 via random allocation (systematic random sampling). Each group received 15 drops of propolis or persica mouthwashes three times a day for 10 days. Pain intensity was recorded by measuring the score of Visual Analogue Scale (VAS) and the diameter of minor aphthous lesions (in mm) at three periods of before treatment, and on the second and sixth days after treatment. Data were analyzed by Mann-Whitney test.
Results: There was no significant difference between pain intensity and ulcer size before treatment and on the second day of treatment. The pain intensity on day 6 was significantly lower in Persica group (P=0.045) but no difference was observed in the mean ulcer size on day 6 between the two groups (P=0.104). The rate of pain relief (P=0.031) and reduction of ulcer size (P=0.046) were significantly higher in Persica group.
Conclusion: Propolis and Persica mouthwashes both reduce pain intensity and ulcer size in minor aphthous ulcers, and Persica showed a stronger potential to achieve these goals compared to propolis.
