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Showing 3 results for Inflammation
Curcumin (Extracted from Tumeric) and its Therapeutic Effects
Arezou Khosrojerdi, Kazem Mashayekhi, Hadi Zare Marzouni,
Volume 4, Issue 2 (10-2016)
Abstract

Background and Objectives:  The application of herbal medicine has been rising in recent years. Therefore, it is logical to revise and revive these traditional drugs while identifying their mechanisms of action can result in developing new treatments for many diseases. Curcumin is the most important component of Turmeric with numerous therapeutic properties. We aimed to review the anti-inflammatory and anti-microbial properties of Curcumin and introduce it as a therapeutic molecule in the present article.

Methods: In this review, 121 articles were selected from authenticated electronic resources and scientific library databases such as Pubmed, Medline, Sciencedirect, WOS, DOAJ, SID, Iranmedex, Magiran and Google Scholar search engine in which Curcumin (Turmeric) had been evaluated as a therapeutic molecule from differeny aspects.

Results: Our findings from the literature revealed that immune responses against infectious and inflammatory factors could be fascilitated by Curcumin. However, the low solubility in water and minimal bioavailability which may lead to poor absorbance from gastrointestinal tract, quick metabolization and elimination from blood circulation are the most important problems during oral consumption.

Conclusion: According to the results of the present review article, Curcumin possesses efficient anti-inflammatory, anti-microbial, anti-viral and anti-parasitic properties. However, the low bioavailability of this substance has limited its treatment properties. Nowadays, several mechanisms have been proposed to increase the bioavailability which can improve its absorption.


The Health-Related Biological Effects of Date Palm Pollen (DPP) along with Physical Activity: A Narrative Mini-Review
Soheil Abdollahi, Mohammad Ali Azarbayjani, Maghsoud Peeri, Saleh Rahmati-Ahmadabad,
Volume 10, Issue 4 (12-2022)
Abstract
Date Palm Pollen (DDP), which is found in the male date tree, actually fertilizes the female date tree, which is necessary for the growth of date fruit. It is consisting of sugarcane, protein, calcium, vitamins (B, C and E) and minerals. It has long been used in traditional medicine as a medicinal plant with fertility effects and increased libido. The information obtained from the studies shows that this pollen, due to its antioxidant and gonadotropin-stimulating compounds, can increase fertility and sexual potency in both women and men with two main mechanisms. The first mechanism is this effect on the stimulation of gonadotrophic hormones and the second is a reduction of oxidative stress in the testicular tissue and consequently a protective effect on the testicular tissue. Due to the presence of antioxidant compounds, the consumption of this pollen also applies its health-enhancing effects to other tissues such as the liver, intestines, and heart. As same as DDP, regular Physical Activity (PA) stimulates gonadotrophic hormones and also beneficially affects antioxidant status and redox balance. In recent years, researchers have paid attention to this pollen as an important factor to strengthen the health-enhancing effects of PA, and researchers have investigated the simultaneous effect of this pollen and PA. Despite the few studies done, it seems that this pollen can enhance the antioxidant and anti-inflammatory effects of regular PAs. Nevertheless, it seems necessary to further studies in this area.

Comparison of twelve weeks periodized circuit resistance training and traditional resistance training on calprotectin levels in obese men
Fatemeh Mirzaei Ashrafi, Seyed Mohsen Avandi, Ali Khaleghian,
Volume 11, Issue 1 (7-2023)
Abstract
Fatemeh Mirzaei Ashrafi http://jorjanijournal.goums.ac.ir/files/0allsites/images/orcid.png, Seyed Mohsen Avandi  http://jorjanijournal.goums.ac.ir/files/0allsites/images/orcid.png , Ali Khaleghian http://jorjanijournal.goums.ac.ir/files/0allsites/images/orcid.png

Background: Obesity has become a significant health concern in recent decades, characterized by increased body fat. This study aimed to compare the effects of circuit and traditional resistance training on serum calprotectin levels in obese men.
Methods: A pre-test-post-test design was used with thirty-three sedentary young obese men (age 21.33±2.49 years, weight 92.23±14.39 kg and BMI 30.71±4.63 kg/m²) who were randomly divided into two groups: experimental and control. The experimental group underwent a 12-week periodized resistance training program consisting of three sessions per week, gradually increasing in intensity from 50% to 80% of their one-repetition maximum (1RM) using a wave pattern. Resting serum calprotectin levels were measured before and after the intervention. Data were analyzed using analysis of variance (ANOVA) and paired sample t-tests, with statistical significance at p < 0.05.
Results: Both periodized circuit and traditional resistance training resulted in increased plasma levels of calprotectin compared to the control group (p = 0.001). Additionally, the periodized circuit resistance training group demonstrated a greater increase in plasma levels of calprotectin than the traditional resistance training and control groups (p = 0.01).
Conclusion: These findings suggest that twelve-week periodized circuit and traditional resistance training programs can effectively increase calprotectin levels in obese men.

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