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Showing 6 results for Fertility

Seyed Mostafa Ghavami, Nahideh Gharehaghaji,
Volume 4, Issue 1 (5-2016)
Abstract

Background & Objectives: In spite of rapid development and arrival of newer medical imaging modalities such as computed tomography and magnetic resonance imaging, hysterosalpingography (HSG) has a great role among imaging techniques because of its enormous advantages. HSG is the standard screening test for the diagnosis of tubal infertility and can provide useful information about the uterine cavity. The aim of this study was to demonstrate the value of HSG in the evaluation of infertility and to diagnose the tubo-uterine causes of infertility in Tabriz.

Methods: In current study, 1260 patients were investigated for infertility by HSG, patients of both primary and secondary infertility were included except those who have history of acute pelvic infection and allergy to contrast media. This study was conducted at Day Medical Imaging Center in Tabriz-IRAN.

Results: HSG outlined normal uterus cavity, normal tube bilaterally with peritoneal spill in 1045 patients (82.94%) and 215 cases (17.06%) were detected with abnormalities. Among these patients, 78 cases (36.28%) detected with normal uterine shape and block of one tube, 32 (14.88%) patients shows both tubal blockages with normal uterus. There was bicurnate uterus in one patient (0.47%) with blockage of both tubes

Conclusion: The most common abnormal finding was normal uterus cavity with block of one or both tubes. Prevention of the pelvic inflammatory diseases, on time diagnosis and treatment of genital infectious, avoiding unnecessary pelvic surgeries, healthcare improvement and increasing the knowledge of society are the important decreasing factors in the women infertility.


Arezou Bagheri, Mahsa Saadati,
Volume 6, Issue 2 (6-2018)
Abstract

Background and objectives: Birth spacing is an important variable for identification of fertility acceleration, total fertility rate, and maternal and fetal health. Therefore, special attention has been paid to this issue by researchers in the fields of medical sciences, health, and population. In addition, proper analysis of this concept is of foremost importance. Application of classical analytical techniques with no attention to their assumptions (e.g., independence of events) is associated with inefficient results. As such, this study aimed to present frailty models as effective models for this analysis.
Methods: Frailty models consider the dependence between unobserved intervals and dispersions by exerting a random impact on the model. Different types of these models include shared, conditional, correlated and time-dependent frailty, each of which along with their applications were presented in the current research using two examples. Results: In practice, the shared frailty model is highly applied due to its simplicity. Nevertheless, since most of the unknown factors affecting the birth spacing are not common between different births, the shared frailty models must be used with caution.
Conclusion: Use of classical statistical methods, such as the Cox proportional hazards model, the important assumption of which is the dependence of events occurred, is not appropriate for the accurate analysis of birth spacing. On the other hand, frailty models consider the correlation between the intervals and are an effective method for analysis of birth spacing, use of which is recommended to researchers in fields of medicine and population.
Telnaz Bahrami, Masoud Maleki,
Volume 7, Issue 2 (7-2019)
Abstract

Infertility is a disorder of the reproductive system, which often occurs after one year of regular unprotected intercourse with the aim of pregnancy. Several physical functions require the synthesis of steroid hormones, in which gonadal steroids (estrogen and progesterone) play a pivotal role in reproduction. Follicular growth and ovulation depend on the proliferation and differentiation of the granulosa and theca cells, which are possible in the steroid pathway after stimulation with the ovarian gonadotropins and cytokines. Steroidization is initiated with the transfer of cholesterol by the StAR protein to the mitochondrial membrane of the steroid cells, which is followed by a cascade of steroid hormones. Recent studies have highlighted the impact of epigenetic mechanisms on reproduction, emphasizing the importance of these changes in the early and secondary stages of gametogenesis. To determine the causes of infertility, it is essential to recognize the altered epigenetic modifications of the relevant gene and its mechanisms. In the present study, the H3K4me3 methylation level was evaluated in the StAR gene regulatory region in the granulosa cells collected from the fertile and infertile women referring to Tabriz Jihad Infertility Centerin Tabriz, Iran using ChIP-qPCR. According to the results, the H3K4me3 methylation level increased in the StAR gene regulatory region in the fertile women compared to the infertile women. In addition, a significant correlation was observed between the follicle and egg rates at the MII stage and the level of this methylation.
Maryam Kazemipoor, Fatemeh Owlia, Mehri Esfandyar, Ali Dehghani, Hossein Fallahzadeh, Amir Houshang Mehrparvar, Mohammad Javad Zare Sakhvidi, Masoud Mirzaei,
Volume 7, Issue 2 (7-2019)
Abstract

Backgrounds and Objectives: Afew large population-based studies have been conducted on the prevalence of oral mucosal lesions in relation to fertility status in the Iranian population. The aim of study was determine the prevalence of oral mucosal lesions in relation to fertility status in women participants of Shahedieh cohort study. 
Materials and Methods: A descriptive cross-sectional study was conducted on 4935 women who participated in the Shahedieh cohort study. The age range of participants was 35-71 years with a mean age of 47.12 years. The prevalence of oral mucosal lesions considering fertility variables including pregnancy, number of pregnancy, oophorectomy, tubectomy, hysterectomy, infertility, menopause, normal menopause, and abortion, application of infertility and oral contraceptive drugs and hormone replacement therapy were recorded.
 Results: The total prevalence of oral mucosal lesions in the studied women were 3.8%. The most commonly affected age group was 40-49 years, followed by 30-39, 50-59 and 60-71 years, respectively. Considering the fertility variables, only menopause (P=0.047) and normal menopause (P=0.024) significantly related to the prevalence of oral mucosal lesions.
Conclusions: The findings of the present study provide information on the prevalence of the oral mucosal lesions considering fertility status in a large population-based study in Iran. With due attention to the higher prevalence of oral mucosal lesions in menopause women, an improved comprehension of oral manifestations at menopause and preventive and treatment approaches during this period should be programmed with health care services to meet the needs of patients deservingly.
 

Fahimeh Hosseinabadi, Tayebeh Faraji, Mahdi Malmir,
Volume 9, Issue 4 (12-2021)
Abstract

Background and Objective: Quercetin is a polyphenolic flavonoid compound with a potent antioxidant impact, proposed to make a drastic contribution in treating male infertility. The current systematic review aimed to provide an overview of previous studies about quercetin's impact on male infertility.
Material and Methods: Electronic search with MeSH words including Quercetin, Infertility, Sperm, Testicular tissue, and Sex hormones was accomplished in databases Web of Science, Scopus, Science Direct, Wiley, NCBI, and Google Scholar. Finally, 296 articles were recognized during the primary search. A total of 144 papers,passing the analysis stage containing Identification, Screening, and Eligibility were selected for assessment.
Results: Quercetin prevents damage to the testicular germinal epithelium and facilitates the spermatogenesis process by strengthening the antioxidant system, reducing lipid peroxidation and oxidative stress, preventing the expression of pro-apoptotic genes, increasing testosterone and gonadotropins.
Conclusion: In conclusion, the present review showed that quercetin by its antioxidant impacts, can counteract various toxins that induce oxidative stress in the male reproductive system.

Soheil Abdollahi, Mohammad Ali Azarbayjani, Maghsoud Peeri, Saleh Rahmati-Ahmadabad,
Volume 10, Issue 4 (12-2022)
Abstract

Date Palm Pollen (DDP), which is found in the male date tree, actually fertilizes the female date tree, which is necessary for the growth of date fruit. It is consisting of sugarcane, protein, calcium, vitamins (B, C and E) and minerals. It has long been used in traditional medicine as a medicinal plant with fertility effects and increased libido. The information obtained from the studies shows that this pollen, due to its antioxidant and gonadotropin-stimulating compounds, can increase fertility and sexual potency in both women and men with two main mechanisms. The first mechanism is this effect on the stimulation of gonadotrophic hormones and the second is a reduction of oxidative stress in the testicular tissue and consequently a protective effect on the testicular tissue. Due to the presence of antioxidant compounds, the consumption of this pollen also applies its health-enhancing effects to other tissues such as the liver, intestines, and heart. As same as DDP, regular Physical Activity (PA) stimulates gonadotrophic hormones and also beneficially affects antioxidant status and redox balance. In recent years, researchers have paid attention to this pollen as an important factor to strengthen the health-enhancing effects of PA, and researchers have investigated the simultaneous effect of this pollen and PA. Despite the few studies done, it seems that this pollen can enhance the antioxidant and anti-inflammatory effects of regular PAs. Nevertheless, it seems necessary to further studies in this area.


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