Abdossaleh Zar, Fatemeh Ahmadi, Hamid Reza Sadeghipour, Abolfazl Shayan Nooshabadi,
Volume 8, Issue 2 (7-2020)
Abstract
Background and objective: Tobacco consumption is one of the hazardous factors that affect people’s quality of life and quality of sleep. This study aimed to compare components quality of sleep in physically active and inactive people tobacco consumers.
Methods: Tobacco consumers in Shiraz were the statistical population of this comparative study. That 470 people of them Participated in the study. Pittsburgh sleep quality questionnaire (PSQI) was used for data collection.
Results: physically active tobacco consumers compared with inactive tobacco consumers obtained significantly better scores in total PSQI score (p = 0.006) and subscales such as daytime dysfunction (p = 0.007), sleep duration (p = 0.002), sleep latency (p = 0.01), subjective sleep quality (p = 0.03).
Conclusion: Exercise and physical activity can have a positive effect on the quality of sleep in tobacco consumers. Findings can inform interventions designed to improve sleep quality via increasing opportunities for exercise among smokers.
Hossein Eidizadeh, Seyed Mohsen Avandi, Abdosalleh Zar, Hamid Reza Sadeghipour,
Volume 12, Issue 1 (10-2024)
Abstract
Background: Resistance training and protein supplementation are known to increase protein synthesis and hypertrophy, primarily through the activation of the mTORC1 signaling pathway. However, mTORC1 activation in the kidneys can potentially lead to kidney disease. This study investigates the effects of eight weeks of resistance training combined with Spirulina platensis supplementation on the RAGs/Rheb/mTOR/S6K pathway in male rat kidneys.
Methods: In this study, 32 male Sprague-Dawley rats were divided into four groups: control (Co; n = 8), Spirulina platensis (SP; n = 8), resistance training (RE; n = 8), and Spirulina platensis + resistance training (SP+RE; n = 8). The resistance training group engaged in five sessions per week over eight weeks. Spirulina was administered at a dosage of 200 mg/kg/day to the supplement and SP+RE groups. Gene expression was analyzed using real-time PCR following the last training session.
Results: The mTOR gene expression significantly increased in the SP group (p = 0.01), while no significant changes were observed in the RE and SP+RE groups. Rheb gene expression did not show significant changes across any groups. Significant changes were noted in the RAGs gene in the SP group (p = 0.001), RE group (p = 0.047), and SP+RE group (p = 0.025). The S6K gene showed significant changes in the SP group (p = 0.01) but not in the other groups.
Conclusion: Spirulina supplementation may activate the mTORC1 signaling pathway in the kidneys, potentially contributing to kidney disease progression. However, combined resistance training and Spirulina supplementation did not show changes in mTORC1 expression, suggesting that this combination might prevent further kidney tissue damage in athletes.
