Samaneh Jadidi , Seyed Mohsen Avandi, Ali Khaleghian ,
Volume 11, Issue 1 (7-2023)
Abstract
Samaneh Jadidi,
Seyed Mohsen Avandi 
,
Ali Khaleghian
Background: Obesity is one of the most serious health problems associated with inflammation. It has been found that functional and resistance physical activities improve obesity and inflammation. The aim of this study was to investigate the effect High-intensity Functional training (HIFT) and Circuit resistance training (CRT) on serum levels of the pro-inflammatory factor interferon gamma (IFN-γ) in obese women.
Methods: Thirty-six obese women of Semnan city (age: 32.66 ± 3.91, weight: 86.97± 9.08 and BMI> 30) were selected and divided into three groups of HIIF (n =12), CRT (n = 12) and control (n = 12) were divided. HIIF was performed in the form of cross-fit exercises and Circuit exercises in the form of weight training for 6 weeks. Finally, the IFN-γ was measured using the Human IFN-g Elisa kit 96t-zellbio. To examine the data, one-way analysis of variance and dependent t-test at the level of p≤0.05 were used and all calculations were performed using SPSS software version 24.
Results: The results showed that there was no significant change in IFN-γ level in training groups compared to before training (P>0.05). Also, the results between groups did not show a significant difference in serum IFN-γ between HIIF and CRT (P>0.05).
Conclusion: Therefore, it seems that of exercise does not affect the dependent variable of serum interferon gamma levels.
Fatemeh Mirzaei Ashrafi, Seyed Mohsen Avandi, Ali Khaleghian,
Volume 11, Issue 1 (7-2023)
Abstract
Fatemeh Mirzaei Ashrafi , Seyed Mohsen Avandi , Ali Khaleghian
Background: Obesity has become a significant health concern in recent decades, characterized by increased body fat. This study aimed to compare the effects of circuit and traditional resistance training on serum calprotectin levels in obese men.
Methods: A pre-test-post-test design was used with thirty-three sedentary young obese men (age 21.33±2.49 years, weight 92.23±14.39 kg and BMI 30.71±4.63 kg/m²) who were randomly divided into two groups: experimental and control. The experimental group underwent a 12-week periodized resistance training program consisting of three sessions per week, gradually increasing in intensity from 50% to 80% of their one-repetition maximum (1RM) using a wave pattern. Resting serum calprotectin levels were measured before and after the intervention. Data were analyzed using analysis of variance (ANOVA) and paired sample t-tests, with statistical significance at p < 0.05.
Results: Both periodized circuit and traditional resistance training resulted in increased plasma levels of calprotectin compared to the control group (p = 0.001). Additionally, the periodized circuit resistance training group demonstrated a greater increase in plasma levels of calprotectin than the traditional resistance training and control groups (p = 0.01).
Conclusion: These findings suggest that twelve-week periodized circuit and traditional resistance training programs can effectively increase calprotectin levels in obese men.
Hossein Eidizadeh, Seyed Mohsen Avandi, Abdosalleh Zar, Hamid Reza Sadeghipour,
Volume 12, Issue 1 (10-2024)
Abstract
Background: Resistance training and protein supplementation are known to increase protein synthesis and hypertrophy, primarily through the activation of the mTORC1 signaling pathway. However, mTORC1 activation in the kidneys can potentially lead to kidney disease. This study investigates the effects of eight weeks of resistance training combined with Spirulina platensis supplementation on the RAGs/Rheb/mTOR/S6K pathway in male rat kidneys.
Methods: In this study, 32 male Sprague-Dawley rats were divided into four groups: control (Co; n = 8), Spirulina platensis (SP; n = 8), resistance training (RE; n = 8), and Spirulina platensis + resistance training (SP+RE; n = 8). The resistance training group engaged in five sessions per week over eight weeks. Spirulina was administered at a dosage of 200 mg/kg/day to the supplement and SP+RE groups. Gene expression was analyzed using real-time PCR following the last training session.
Results: The mTOR gene expression significantly increased in the SP group (p = 0.01), while no significant changes were observed in the RE and SP+RE groups. Rheb gene expression did not show significant changes across any groups. Significant changes were noted in the RAGs gene in the SP group (p = 0.001), RE group (p = 0.047), and SP+RE group (p = 0.025). The S6K gene showed significant changes in the SP group (p = 0.01) but not in the other groups.
Conclusion: Spirulina supplementation may activate the mTORC1 signaling pathway in the kidneys, potentially contributing to kidney disease progression. However, combined resistance training and Spirulina supplementation did not show changes in mTORC1 expression, suggesting that this combination might prevent further kidney tissue damage in athletes.
Sara Valikhani, Seyed Mohsen Avandi, Mehdi Hedayati ,
Volume 12, Issue 3 (12-2024)
Abstract
Background: Circuit resistance training, beneficial to overweight individuals, combines aerobic and resistance exercises. This study aimed to investigate the effect of multi-joint circuit resistance training on serum adiponectin levels and lipid profiles in overweight women.
Methods: Thirty sedentary overweight women (mean age of 34.48±4.304 years, mean weight of 81.17±9.137 kg, and mean BMI of 30.17±2.13 kg/m2) were randomly divided into two groups: circuit resistance training (n=15) and a control group (n=15). The experimental group trained at 65–85% of maximum heart rate for eight weeks, with three sessions per week (24 sessions total). The control group did not engage in regular exercise. Serum adiponectin levels and lipid profiles were assessed before and after the intervention. Data were analyzed using paired sample t-tests and dependent t-tests at a significance level of P-value≤0.05.
Results: The results showed that adiponectin levels (P-value=0.001) and cholesterol levels (P-value=0.015) increased in the circuit training group, while LDL levels decreased (P-value=0.031). HDL levels increased but were not statistically significant (P-value=0.100). These variables did not change in the control group.
Conclusion: Finding ways to improve the state of adipokines is of vital importance for these patients. According to the results, circuit resistance training may be an effective method for addressing dyslipidemia and increasing adiponectin levels in overweight women.
