Volume 7, Issue 2 (7-2019)
Jorjani Biomed J 2019, 7(2): 21-30 |
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Kazemipoor M, Owlia F, Esfandyar M, Dehghani A, Fallahzadeh H, Mehrparvar A H, et al . Prevalence of oral mucosal lesions considering fertility status in women of Shahedieh cohort population. Jorjani Biomed J 2019; 7 (2) :21-30
URL: http://goums.ac.ir/jorjanijournal/article-1-655-en.html
URL: http://goums.ac.ir/jorjanijournal/article-1-655-en.html
Maryam Kazemipoor1 
, Fatemeh Owlia2 , Mehri Esfandyar 3, Ali Dehghani4 , Hossein Fallahzadeh5 , Amir houshang Mehrparvar6 , Mohammad Javad Zare Sakhvidi7 , Masoud Mirzaei5
, Fatemeh Owlia2 , Mehri Esfandyar 3, Ali Dehghani4 , Hossein Fallahzadeh5 , Amir houshang Mehrparvar6 , Mohammad Javad Zare Sakhvidi7 , Masoud Mirzaei5
1- Department of Endodontics, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2- Department of oral medicine, School of dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3- Department of Endodontics, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran ,dr.endo2015@gmail.com
4- Department of Biostatistics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
5- Research Centers of Prevention & Epidemiology of Non-Communicable Disease, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
6- Department of Occupational Medicine, Shahid Sadoughi University of Medical sciences, Yazd, Iran
7- Occupational Health Research Center, School of Public health, Shahid Sadoughi of University of Medical Sciences, Yazd, Iran
2- Department of oral medicine, School of dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3- Department of Endodontics, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran ,
4- Department of Biostatistics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
5- Research Centers of Prevention & Epidemiology of Non-Communicable Disease, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
6- Department of Occupational Medicine, Shahid Sadoughi University of Medical sciences, Yazd, Iran
7- Occupational Health Research Center, School of Public health, Shahid Sadoughi of University of Medical Sciences, Yazd, Iran
Abstract: (7788 Views)
Backgrounds and Objectives: Afew large population-based studies have been conducted on the prevalence of oral mucosal lesions in relation to fertility status in the Iranian population. The aim of study was determine the prevalence of oral mucosal lesions in relation to fertility status in women participants of Shahedieh cohort study.
Materials and Methods: A descriptive cross-sectional study was conducted on 4935 women who participated in the Shahedieh cohort study. The age range of participants was 35-71 years with a mean age of 47.12 years. The prevalence of oral mucosal lesions considering fertility variables including pregnancy, number of pregnancy, oophorectomy, tubectomy, hysterectomy, infertility, menopause, normal menopause, and abortion, application of infertility and oral contraceptive drugs and hormone replacement therapy were recorded.
Results: The total prevalence of oral mucosal lesions in the studied women were 3.8%. The most commonly affected age group was 40-49 years, followed by 30-39, 50-59 and 60-71 years, respectively. Considering the fertility variables, only menopause (P=0.047) and normal menopause (P=0.024) significantly related to the prevalence of oral mucosal lesions.
Conclusions: The findings of the present study provide information on the prevalence of the oral mucosal lesions considering fertility status in a large population-based study in Iran. With due attention to the higher prevalence of oral mucosal lesions in menopause women, an improved comprehension of oral manifestations at menopause and preventive and treatment approaches during this period should be programmed with health care services to meet the needs of patients deservingly.
Materials and Methods: A descriptive cross-sectional study was conducted on 4935 women who participated in the Shahedieh cohort study. The age range of participants was 35-71 years with a mean age of 47.12 years. The prevalence of oral mucosal lesions considering fertility variables including pregnancy, number of pregnancy, oophorectomy, tubectomy, hysterectomy, infertility, menopause, normal menopause, and abortion, application of infertility and oral contraceptive drugs and hormone replacement therapy were recorded.
Results: The total prevalence of oral mucosal lesions in the studied women were 3.8%. The most commonly affected age group was 40-49 years, followed by 30-39, 50-59 and 60-71 years, respectively. Considering the fertility variables, only menopause (P=0.047) and normal menopause (P=0.024) significantly related to the prevalence of oral mucosal lesions.
Conclusions: The findings of the present study provide information on the prevalence of the oral mucosal lesions considering fertility status in a large population-based study in Iran. With due attention to the higher prevalence of oral mucosal lesions in menopause women, an improved comprehension of oral manifestations at menopause and preventive and treatment approaches during this period should be programmed with health care services to meet the needs of patients deservingly.
Type of Article: Original article |
Subject:
Health
Received: 2019/03/20 | Accepted: 2019/05/12 | Published: 2019/07/1
Received: 2019/03/20 | Accepted: 2019/05/12 | Published: 2019/07/1
References
1. Mandal R, Basu P. Cancer screening and early diagnosis in low and middle income countries: Current situation and future perspectives. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2018;61(12):1505-12. Epub 2018/10/26. Krebsvorsorge und Fruherkennung in Landern mit niedrigem und mittlerem Einkommen : Aktuelles Szenario und Zukunftsperspektiven. [DOI] [Google Scholar]
2. Suri V, Suri V. Menopause and oral health. Journal of mid-life health. 2014;5(3):115-20. Epub 2014/10/16. [DOI] [Google Scholar]
3. Rabiei M, Leili EK, Alizadeh L. Burning Mouth Syndrome: A Comparative Cross-sectional Study. Contemporary clinical dentistry. 2018;9(Suppl 2):S256-S60. Epub 2018/10/09. [DOI] [Google Scholar]
4. Sun WL, Lei LH, Chen LL, Yu ZS, Zhou JW. Multiple gingival pregnancy tumors with rapid growth. J Dent Sci. 2014;9(3):289-93. [DOI] [Google Scholar]
5. Kushlinskii NE, Nagibin AA, Laptev PI, Parshikova SM, Bassalyk LS, Matiakin EG, et al. Sex steroid hormone receptors in the cytosolic fraction of cancer and leukoplakia of the oral mucosa. Stomatologiia. 1993;72(4):18-22. Epub 1993/10/01. Retseptory polovykh steroidnykh gormonov v tsitozol'noi fraktsii raka i leikoplakii slizistoi obolochki polosti rta. [Google Scholar]
6. Dutt P, Chaudhary S, Kumar P. Oral health and menopause: a comprehensive review on current knowledge and associated dental management. Annals of medical and health sciences research. 2013;3(3):320-3. Epub 2013/10/12. [DOI] [Google Scholar]
7. Sawczuk B, Gołębiewska M, Mazurek A, Chyczewski L. Evaluation of estrogen receptor-β expression in the epithelium of the oral mucosa in menopausal women under hormone replacement therapy. Advances in medical sciences. 2014 Mar 1;59(1):85-9. [DOI] [Google Scholar]
8. Ojanotko-Harri A, Forssell H, Laine M, Hurttia H, Blauer M, Tuohimaa P. Immunohistochemical detection of androgen receptors in human oral mucosa. Archives of oral biology. 1992;37(6):511-4. Epub 1992/01/01. [DOI] [Google Scholar]
9. Andreasen JO, Pindborg JJ, Hjorting-Hansen E, Axell T. Oral health care: more than caries and periodontal disease. A survey of epidemiological studies on oral disease. International dental journal. 1986;36(4):207-14. Epub 1986/12/01. [Google Scholar]
10. Ikeda N, Handa Y, Khim SP, Durward C, Axell T, Mizuno T, et al. Prevalence study of oral mucosal lesions in a selected Cambodian population. Community dentistry and oral epidemiology. 1995;23(1):49-54. Epub 1995/02/01. [DOI] [Google Scholar]
11. Zain RB, Ikeda N, Razak IA, Axéll T, Majid ZA, Gupta PC, Yaacob M. A national epidemiological survey of oral mucosal lesions in Malaysia. Community dentistry and oral epidemiology. 1997 Oct;25(5):377-83. [DOI] [Google Scholar]
12. Al-Mobeeriek A, AlDosari AM. Prevalence of oral lesions among Saudi dental patients. Annals of Saudi medicine. 2009;29(5):365-8. Epub 2009/08/25. [DOI] [Google Scholar]
13. Jahanbani J, Sandvik L, Lyberg T, Ahlfors E. Evaluation of oral mucosal lesions in 598 referred Iranian patients. The open dentistry journal. 2009;3:42-7. Epub 2009/05/16. [DOI] [Google Scholar]
14. Prasanna J, Karunakar P, Sravya MVN, Madhavi B, Manasa A. Detrimental consequences of women life cycle on the oral cavity. J Oral Res Rev. 2018;10(1):39-44. [DOI] [Google Scholar]
15. Forabosco A, Criscuolo M, Coukos G, Uccelli E, Weinstein R, Spinato S, et al. Efficacy of hormone replacement therapy in postmenopausal women with oral discomfort. Oral surgery, oral medicine, and oral pathology. 1992;73(5):570-4. Epub 1992/05/01. [DOI] [Google Scholar]
16. Khosravisamani M, Maliji G, Seyfi S, Azadmehr A, Abd Nikfarjam B, Madadi S, et al. Effect of the menstrual cycle on inflammatory cytokines in the periodontium. Journal of periodontal research. 2014;49(6):770-6. Epub 2014/03/29. [DOI] [Google Scholar]
17. Chaitra TR, Manuja N, Sinha AA, Kulkarni AU. Hormonal effect on gingiva: pubertal gingivitis. BMJ case reports. 2012;2012. Epub 2012/08/29. [DOI] [Google Scholar]
18. Bercovici B, Gron S, Pisanty S. Vaginal and oral cytology of the menopause. A comparative study. Acta cytologica. 1985;29(5):805-9. Epub 1985/09/01. [Google Scholar]
19. Wardrop RW, Hailes J, Burger H, Reade PC. Oral discomfort at menopause. Oral surgery, oral medicine, and oral pathology. 1989;67(5):535-40. Epub 1989/05/01. [DOI] [Google Scholar]
20. Leimola-Virtanen R, Salo T, Toikkanen S, Pulkkinen J, Syrjanen S. Expression of estrogen receptor (ER) in oral mucosa and salivary glands. Maturitas. 2000;36(2):131-7. Epub 2000/09/28. [DOI] [Google Scholar]
21. Maturana-Ramirez A, Adorno-Farias D, Reyes-Rojas M, Farias-Vergara M, Aitken-Saavedra J. A retrospective analysis of reactive hyperplastic lesions of the oral cavity: study of 1149 cases diagnosed between 2000 and 2011, Chile. Acta odontologica latinoamericana : AOL. 2015;28(2):103-7. Epub 2015/09/12. [Google Scholar]
22. González RMR, Salas AC, González NBM, Suárez SR. Oral health and social determinants in elderly adults. MOJ Gerontol Ger. 2018;3(1):16-20. [DOI] [Google Scholar]
23. Rivera-Hidalgo F, Shulman JD, Beach MM. The association of tobacco and other factors with recurrent aphthous stomatitis in an US adult population. Oral diseases. 2004;10(6):335-45. Epub 2004/11/10. [DOI] [Google Scholar]
24. Castellanos JL, Diaz-Guzman L. Lesions of the oral mucosa: an epidemiological study of 23785 Mexican patients. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2008;105(1):79-85. Epub 2007/06/15. [DOI] [Google Scholar]
25. Hartnett E, Haber J, Krainovich-Miller B, Bella A, Vasilyeva A, Kessler JL. Oral health in pregnancy. Journal of Obstetric, Gynecologic & Neonatal Nursing. 2016 Jul 1;45(4):565-73. [DOI] [Google Scholar]
26. Nelson HD. Menopause. Lancet (London, England). 2008;371(9614):760-70. Epub 2008/03/04. [DOI]
27. Mutneja P, Dhawan P, Raina A, Sharma G. Menopause and the oral cavity. Indian journal of endocrinology and metabolism. 2012 Jul;16(4):548. [DOI] [Google Scholar]
28. Ferguson MM, Carter J, Boyle P, Hart DM, Lindsay R. Oral complaints related to climacteric symptoms in oophorectomized women. Journal of the Royal Society of Medicine. 1981;74(7):492-8. Epub 1981/07/01. [DOI] [Google Scholar]
29. Volpe A, Lucenti V, Forabosco A, Boselli F, Latessa AM, Pozzo P, et al. Oral discomfort and hormone replacement therapy in the post-menopause. Maturitas. 1991;13(1):1-5. Epub 1991/03/01. [DOI] [Google Scholar]
30. Ree AH, Landmark BF, Eskild W, Levy FO, Lahooti H, Jahnsen T, et al. Autologous down-regulation of messenger ribonucleic acid and protein levels for estrogen receptors in MCF-7 cells: an inverse correlation to progesterone receptor levels. Endocrinology. 1989;124(5):2577-83. Epub 1989/05/01. [DOI] [Google Scholar]
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