دوره 4، شماره 1 - ( بهار 1395 )
جلد 4 شماره 1 صفحات 1-14 |
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Torabian P, Erfani-Moghadam V. Theranostics; Application of Nanosystems for Simultaneous Targeted Therapy and Imaging in Diseases. Jorjani Biomed J 2016; 4 (1) :14-1
URL: http://goums.ac.ir/jorjanijournal/article-1-437-fa.html
URL: http://goums.ac.ir/jorjanijournal/article-1-437-fa.html
ترابیان پدرام، عرفانی مقدم وحید. ترانوستیک (Theranostics) علم کاربرد نانوسیستم ها در درمان هدفمند و تصویربرداری همزمان در بیماری‌ها. فصلنامه علمی پژوهشی زیست پزشکی جرجانی. 1395; 4 (1) :14-1
URL: http://goums.ac.ir/jorjanijournal/article-1-437-fa.html
1- دانشگاه علوم پزشکی گلستان
2- دانشگاه علوم پزشکی گلستان ،vahid.erfani@goums.ac.ir
2- دانشگاه علوم پزشکی گلستان ،
چکیده: (16022 مشاهده)
برای ده ها سال محققان تلاش کرده اند روش هایی با مکانیزم های غیر تخریبی (noninvasive) برای بررسی وضعیت بیماری درون بدن بیمار ابداع نمایند. ظهور نانوتکنولوژی این امکان را فراهم نمود. مقیاس نانو توانایی کشف اولیه بیماری را در مراحل سلولی و قبل از این که بافت بیمار یا تومور به وجود آید، فراهم آورده است که می تواند کمک بزرگی برای درمان بیماری ها باشد. در چند سال اخیر، ترانوستیک (Theranostics) به عنوان یکی از جدیدترین نگرش ها در نانو مطرح شده است که عمل شناسایی و درمان و ردیابی پس از درمان همزمان صورت می پذیرد. بنابراین ترانوستیک را می‌توان نوعی راهبرد درمانی مناسبی برای پزشکی شخصی، فارماکوژنومیکس و تصویربرداری مولکولی دانست تا بدین وسیله بتوان راهی در جهت توسعه درمان‌های نوین پدید آورد و با بهره از درک مولکولی بهتر، در انتخاب داروهای مؤثرتری عمل کرد. درنهایت، محققان بر این باورند که ترانوستیک می تواند در پاسخ به درمان‌ها نظارت داشته و ایمنی و درجه تأثیر دارو را افزایش دهد و از درمان‌های نابجای بیماران جلوگیری کند و درنهایت منجر به کاهش بخش زیادی از هزینه‌های درمان در تمام نظام سلامت گردد. در این مطالعه، به طور اجمالی بخش های ساختاری و برخی قابلیت های کاربردی نانوحامل های ترانوستیک بررسی می شود.
نوع مقاله: مروری |
موضوع مقاله:
پزشکی عمومى
دریافت: 1395/5/23 | پذیرش: 1395/5/23 | انتشار: 1395/5/23
دریافت: 1395/5/23 | پذیرش: 1395/5/23 | انتشار: 1395/5/23
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