Showing 7 results for Azimi
M Azimi, Sh Moghadam, L Jouybari, N Bahnampour, Ea Ghaemi, M Hesam, M Bazori, A Sanagoo,
Volume 8, Issue 2 (summer 2014[PERSIAN] 2014)
Abstract
Abstract
Background and Objective: Bacterial colonization in upper respiratory airways is one of the major risk factors for the development of the ventilator–associated pneumonia (VAP), which is the most common and serious hospital-acquired infection in intensive care unit (ICU). The aim of this study was to determine the frequency of oropharyngeal microorganisms of patients with tracheal tube hospitalized in ICU.
Material and Methods: Of 39 patients hospitalized in ICU of panje Azar Hospital, the oropharyngeal cultures were taken after admission. The samples were evaluated for growth of Staphylococcus aureus, Pneumococcus, Enterococcus, Pseudomonas, and E-coli.
Results: The mean age of the patients (21 men, 18 women) was 43.64±15.01. The culture was positive in 28.2% and the most common isolate was Pseudomonas aeruginosa (10.3%).
Conclusion: Pseudomonas, which is the main pathogen for ventilator- associated pneumonia, may be a potential threat for the patients hospitalized in intensive care units.
Keywords: Microbial Colonization, Endotracheal Tube, Intensive Care Unit, Ventilator Associated Pneumonia
Samira Oladazimi, Parvin Farzanegi, Mohammad Ali Azarbayejani,
Volume 14, Issue 1 (Jan-Feb 2020)
Abstract
ABSTRACT
Background and objectives: Matrix metalloproteinase-13 (MMP-13) and activin receptor-like kinase 5 (ALK5) are considered as important factors contributing to knee osteoarthritis (OA) pathogenesis. Here, we compared therapeutic effects of mesenchymal stem cells (MSCs), ozone and exercise training alone and combined on expression of MMP-13 and ALK5 in rats with knee OA.
Methods: Knee OA was induced by a surgical method. Rats with OA were then randomly divided into several groups, including model, MSCs, ozone, exercise, MSCs + ozone, MSCs + exercise, ozone + exercise and MSCs + ozone + exercise groups. Expression of MMP-13 and ALK5 genes was evaluated using RT-PCR. Data were analyzed using SPSS software at significance of 0.05.
Results: Expression of MMP-13 and ALK5 differed significantly between the study groups (P<0.0001). Knee OA was significantly associated with overexpression of MMP-13 and ALK5 in the cartilage tissue of rats with knee OA. Combined therapy with MSCs, ozone and exercise significantly decreased the expression of MMP-13 and ALK5 in the cartilage of rats with OA (P<0.001). Although MSCs, ozone and exercise training were effective to mitigate expression of MMP-13 and ALK5 genes, ozone therapy was more effective compared to the other two therapies.
Conclusion: Although ozone, MSCs and exercise training alone could decrease the expression of MMP-13 and ALK5 genes, combined therapy with MSC, ozone and exercise is more effective.
Keywords: Osteoarthritis, O3, MSCs, exercise, MMP-13, ALK5.
Alireza Nikonajad, Sadegh Ali Azimi, Abbas Allami, Reza Qasemi Bargi, Alijan Tabarraei,
Volume 15, Issue 1 (Jan-Feb 2021)
Abstract
Objectives: Although extrapulmonary tuberculosis (EPTB) is a secondary target for national TB control programs, its significance has increased worldwide. In order to study the epidemiology of EPTB in the Northeast of Iran, this survey was conducted.
Methods and Methods: A population-based, retrospective analysis of all cases of EPTB during 2012–2015 reported to the TB Unit of the Golestan was performed. Socioeconomic and environmental variables, sites, admission, mode of diagnosis and outcome status were collected. Data analyzed through SPSS 25.0 by descriptive and analytical statistical methods.
Results: A total of 741 cases of EPTB were included. Patients were mainly female (59.1%), age of 0 to 40 years old (57.6%), less than five years of education (46.7%) and mainly Fars (39.6%). Non-native ethnicities significantly acquired EPTB more than native ethnicities (p<0.001). Mortality rate was 5.1%. Smoking detected more frequently in EPTB patients (p<0.001). HIV status of most EPTB patients (89.3%) were unknown. The most common forms were pleural (30.5%) and lymphadenopathy (22.0%). Cultures and PCR performed in only about 10 percent of EPTB patients in our study.
Conclusions: EPTB was more prevalent in non-native population. Improvement of socioeconomic conditions and screening program may be successful in reducing the problem among immigrant
Sadeghali Azimi, Bahareh Bashardoust, Mohammad Hadi Tajik Jalayeri,
Volume 19, Issue 1 (4-2025)
Abstract
Introduction: Bronchopulmonary lophomoniasis is an infrequent occurrence. In this study, we document a singular instance of pulmonary lophomoniasis exhibiting unconventional manifestations in Golestan province, Iran.
Case presentation: The case under examination pertains to a 47-year-old male inmate who has been encountering respiratory issues for a duration of four months, culminating in a diagnosis of lophomoniasis. Both blood and sputum cultures yielded negative results. Similarly, bronchoalveolar lavage tests for bacterial and fungal pathogens returned negative findings. However, bronchoalveolar lavage (BAL) results (microscopic) showed mild positive lophomoniasis targeting Lophomonas blattarum and Serum IgE=387 was relatively higher than normal limits.
Conclusion: The patient received treatment with metronidazole, leading to the resolution of all clinical complications within a span of four weeks.
