M Qureshi, M Zangiabadi, A Ebrahimzadeh,, M Rezaee Firoozabadi, M Rood Bari,
Volume 1, Issue 1 (Spring - Summer 2007 [PERSIAN] 2007)
Abstract
Abstract Background and Objective: Airborne fungi have been proposed as the most common cause of some adverse health effects such as skin, eye and respiratory disorders therefore, we carried out an aerobiological study to determine fungal seasonal frequency in the air of Zahedan, Iran. Materials and Methods: The air samples (n=1080) of this descriptive cross sectional study were obtained, in different hours, from different urban places of zahedan in 2001, and studied via sabouraud dextrose agar(S.D.A). Results: 1917 colonies were found in the 1080 studied plates and indicated that the most Common fungi were aspergillus(41%), penicillium(33%) and rhizopus(6.8%), based on chi square, The fungal frequencies in the evening(39.3%), at noon(38.2%) and in the morning(22.5%) were not statistically different . Highly contaminated area was down town (Bazar) and then hospitals. There was significant correlation (p<0.001) between fungal frequency and the seasons- winter (15.9%) and summer (31.4%). Conclusion: Based on the results, we suggest strongly improving environmental hygienic condition of the buildings and passages and rapid waste material disposal. It seems that the most effective strategy in decreasing fungal disorder is performing some educational programs. Keywords: Fungal agents, air, Zahedan.
Biranvand E, Abedian Kenary S, Ghaheri A, Rezaee M S, Hasannia H, Nasrolahi M, Parsaee Mr, Ahanjan M, Biranvand B, Ahmadi Basiri E,
Volume 5, Issue 1 (spring-summer[PERSIAN] 2011)
Abstract
Abstract Background and objectives: Interferon-Gamma and interferon Gamma receptor (IFNγ ⁄ IFNγR1) are the main genes associated with susceptibility to tuberculosis. We aimed at studying on interferon-Gamma Gene polymorphism(- 56 C/T) in people suffered from tuberculosis (TB). Material and Methods: In this case-control study, the subjects were 62 individuals with TB and 74 healthy ones. Genomic DNA was extracted by DNA isolation kit(Roche Corporation), and genotype identification was performed by polymerase chain reaction-Restriction fragment length polymorphism (PCR-RFLP). Chi square and logistic regression, using SPSS soft ware (version 18), was used to compare genotype and alleles between case and control groups. Results: The frequency of TT genotype in tuberculosis patients and healthy person are 43.5% and 17.5%, respectively. Based on Logistic regression (odd ration 0.148, p=0.0006), there is significant difference between Case and Control. In addition, the frequency of T allele is, in case group, 62.09 % the difference between case and control is significant, based on Logistic regression (odd ratio: 0.418, P=0.028). Conclusion: It is implied that -56C/T is associated with IFNγR1 promoter in tuberculosis patient. It is found to be associated with increased susceptibility to tuberculosis. Key words: Tuberculosis, IFNγR, PCR-RFLP
Sona Rostampour Yasouri, Masoud Ghane, Monir Doudi, Abolhasan Rezaee, Nafiseh Sadat Naghavi,
Volume 14, Issue 6 (Nov-Dec 2020)
Abstract
Leptospirosis is a zoonotic disease with a high incidence rate in many parts of the world due to the presence of various hosts for the pathogenic Leptospira. Tropical, subtropical and humid regions are suitable for long-term survival of the bacterium. Because of the temperate and humid climate, northern areas of Iran are suitable for pathogenic Leptospira and outbreak of the disease. Therefore, identification of infected areas is important from a public health and economic point of view. Previous studies show that the incidence rate of leptospirosis is increasing every year. Therefore, accurate diagnosis, control and prevention of this disease seem necessary through vaccination and raising public awareness, especially among high-risk groups. Today, diagnostic methods including immunofluorescence assay, enzyme-linked immunosorbent assay, microscopic agglutination test (MAT) and polymerase chain reaction (PCR) are used to diagnose the leptospirosis. MAT is the gold standard test for the diagnosis of leptospirosis with extensive applications in Iran. Due to the importance of this disease and its high prevalence in recent years, the present study aimed to investigate the epidemiology and diagnosis of leptospirosis in Iran.
