Showing 2 results for Panahi
J Panahi, Mr Havasian, J Abdi, K Sayehmiri,
Volume 8, Issue 5 (winter[PERSIAN] 2015)
Abstract
Abstract In this study, the prevalence of Echinococcus granulosus was surveyed by meta-analysis and systematic review. Using main keywords of Echinococcus granulosus, dog and carnivores, we searched standard sites such as Google scholar, SID, Pubmed, Iranmedex, Irandoc, Science direct and magiran. Fifteen reliable articles were reviewed and analyzed by STATA software, Ver 11. From obtained articles, the number of 2271 dogs, 167 jackals and 174 foxes have been investigated by Iranian researchers. The infection rate of E.granulosus was reported 27.4% (95% CI, 20.9-33.9) in this study in that the highest from north and north west of Iran with prevalence of 33.3 %(CI:22.1-44.4), the lowest by 21.9 %(CI:12.5-31.3) from west and south west of Iran and the average from the central region of Iran ( 26.9% CI:12.8-41). Among cities the highest (64%) and the lowest (3.3%) infection rate were reported in Garmsar city (2010) and Sistan and Balochestan province (1997). Given that the overall prevalence of E.granulosus in Iran is high, Control and prevention measures including destruction of stray dogs and treatment of owner dogs seems to be necessary. Keywords: Echinococcus Granulosus, Carnivores, Iran, Systematic Review
Tahereh Panahi, Leila Asadpour, Najmeh Ranji,
Volume 19, Issue 1 (4-2025)
Abstract
Background and Objectives: Infections caused by extended-spectrum β-lactamase (ESBL) producing Pseudomonas aeruginosa are a serious concern in hospitals around the world. Many of β-lactamase genes are carried by integrons. This study was conducted to investigate the frequency of β-lactamase genes and characterize class 1 integrons in multidrug-resistant P. aeruginosa strains in Guilan, northern Iran.
Methods: A total of 110 P. aeruginosa isolates were collected from different hospitals in 2021 and identified using standard microbiological methods. The isolates were studied for their antibacterial susceptibility and ESBL-producing ability by disk diffusion. All ESBL-producing isolates were investigated for the presence of β-lactamase resistant and integron genes by polymerase chain reaction (PCR). Gene cassette screening was done based on sequence analysis of class 1 integrons.
Results: Based on antibiotic susceptibility testing, 40 isolates (37.4%) were ESBL producers. The frequency of β-lactamase genes including VIM, SIM, IMP, SPM, and OXA2 was 10.3%, 1.9%, 20.6%, 14%, and 4%, respectively. GIM and OXA 10 genes were not found in any of the strains. Furthermore, int1 gene was identified among 37 isolates (34.6%). The sequencing results of int1 showed 12 different types of gene cassettes among 13 strains. In this assay, blaOXA-2 was the only bla gene identified in int1.
Conclusion: The results of the present study showed that integrons carrying multidrug resistance genes are highly prevalent in P. aeruginosa isolates and ESBL genes were also observed in these strains. Therefore, constant monitoring of drug resistance, especially ESBL producers, is critical to disease management in clinical settings.
