Showing 13 results for Ayatollahi
Koohsar F, Amini A, Ayatollahi A A, Noshak Gh, Hedayatmofidi H S, Namjoo M,
Volume 6, Issue 1 (spring-summer[PERSIAN] 2012)
Abstract
Abstract Background and objectives: Food handlers could be the main sources of intestinal parasite transmission in case of not observing the hygienic rules. Contamination can be decreased by screening food handlers through physical exam and laboratory tests. The aim of this study was determining the prevalence of intestinal parasites in 2010. Material and Methods: This cross-sectional research was carried out on 500 randomly selected individuals engaged in different food related careers. After filling out the questionnaire sheets, two specimens of feces were collected from each person and tested by brine 30% (floatation) and direct methods. Result: The results show that the prevalence of intestinal parasites is 6%. The highest prevalence is relateted to Giardia lamblia ( 17 4.3%) and the lowest to Hymenolepis nana ( 3 0.6%). in the age group of 60-51 years (11.8%) and individuals who just able to read and write (7.4%) The highest percentage is observed. The Most contamination is reported in butchery staff (25%) and the lowest in people worked in butler's pantry, without parasitic infections. Conclusion: The prevalence of intestinal parasitic infections are high relatively, especially pathogenic protozoan therefore, it is important be careful about health status of these individuals and their role in the spread of pollution. Key words: Intestinal Parasites, Food Handlers, Prevalence, Gorgan
S Royani, S Alijanpor, Z Shirbaghaei, R Khorasaninejad, Gh Roshandel, Aa Ayatollahi, Hr Joshaghani,
Volume 7, Issue 3 (Autumn 2013)
Abstract
Abstract
Background and Objective: Of the most common hypochromic microcytic anemia are iron deficiency anemia and minor thalassemia, which are common in Iran and their differential diagnosis is extremely important. The level of 25-hydroxy vitamin D is the indication of vitamin D blood status. The aim of this study was to compare serum levels of vitamin D in people with minor thalassemia and iron deficiency anemia with healthy subjects in order to investigate the relationship between vitamin D deficiency and iron absorption.
Material and Methods: In this case-control study, 24 patients with minor thalassemia, 20 patients with iron deficiency anemia and 24 healthy individuals participated. Groups were matched for age and sex. Testing of Vitamin D level by ELISA, ferritin by quantitative luminescence method and HbA2 by column chromatography was carried out.
Results: The number of individuals with low level of vitamin D in iron deficiency group is 15 (75%), in minor thalassemia group is 8 (33/3%) and in the control group 11 (45.8%).
Conclusion: In this study, the highest percentage of vitamin D deficiency is observed in cases with iron deficiency anemia. Because of association between vitamin D and anemia, iron and vitamin D supplementation is recommended to enrich the diet.
Keywords: Anemia Minor Thalassemia Iron Deficiency Anemia Vitamin D
F Koohsar, A Amini, Aa Ayatollahi, F Niknejad, Z Abbasi Nejat,
Volume 7, Issue 3 (Autumn 2013)
Abstract
Abstract
Background and Objective: In many countries, especially in developing countries, diarrheal diseases is one of the most important causes of mortality. In these countries, due to availability transfer conditions of parasitic infections, (pathogenic and non-pathogenic parasite), have a high prevalence. This study aimed was determining the prevalence of Parasites causing diarrhea in Gorgan .
Material and Methods: This cross-sectional study was performed on 1086 Patients with acute diarrhea. The test was performing by the wetmount and formalin-ether concentration method according to WHO protocol.
Results: From 1086 patients in study, 197 (18.1%) were infected by intestinal parasites, that 141 (13%) were infected with Protozoan and 79 (7.27%) were infected with intestinal worms. The prevalence of wet mount method was, Entamoebahistolytica in 69 (6.4%), Giardia lamblia in 27 (2.5%), Entamoeba coli in 15 (1.4%), Chilomastixmesnili in 8 (0.7%), and with formalin-ether method was Hymenolepis nana in 26 (2.4%), Trichostrongylus in 16 (1.5%), Enterobiusvermicularis in 10 (0.9%).
Conclusion: The high prevalence of Entamoeba histolytica, is indicating protozoan importance as a cause of acute diarrhea.
Keywords: Intestinal Parasites Diarrhea Wetmount Formalin Ether Gorgan
P Farzanegi, Pp Ayatollahi, Ar Barari, M Fakori Joybari, S Shirali, M Shojaee, A Khandandel,
Volume 8, Issue 2 (summer 2014[PERSIAN] 2014)
Abstract
Abstract
Background and Objective: Imbalance Between antioxidant defensive system and increased production of free radicals leads to oxidative stress that can be effective in making cellular damage and causing some diseases such as diabetes. The aim of the current study was to investigate the effect of eight-week purslane extract consumption on some peroxidant and antioxidants indicators in patients with type 2 diabetes.
Material and Methods: The Participants were 16 women with type 2 diabetes who had not the history of once a week regular physical activity program, in previous five years. They were randomly divided into two groups of experimental, purslane supplementation for eight weeks, and control. Blood sampling was performed in two stages.
Results: After eight weeks of purslane consumption, resting levels of MDA, SOD and CAT in Supplementation group showed a significant decrease compared to those of control group.
Conclusion: Purslane consumption can improve peroxidant/antioxidant balance in women with type2 diabetes.
Key words: Purslane, Peroxidant Balance, Antioxidant, Type 2 Diabetes
Al Barari, Aa Ayatollahi, S Shirali, M Ghasemi, A Hosseini, Ar Ekrami, A Khandan Del,
Volume 8, Issue 3 (Autumn[PERSIAN] 2014)
Abstract
Abstract Background and Objective: The hormonal responses are different, according to type, intensity and the duration of training. We aimed to compare the effect of endurance and resistance training in untrained men on the level sexual hormone including testosterone, estradiol, and on sex hormone binding globulin (SHBG). Material and Methods: this study was conducted on male Student Volunteers divided randomly into three groups of eight members, including endurance, resistance and control. To measure the variables, we performed sampling before and after the training program. Results: the levels of testosterone and estradiol, in both groups have a significant (p<0.05) increase and decrease respectively. SHBG level was significantly increased only in endurance group (p<0.05), But LH level was meaningfully increased only in the resistance group (p<0.05). Conclusion: The endurance and resistance training can increase the production of testosterone .Increased testosterone and decreased estradiol in men lead to sperm production and improve fertility. Keywords: Endurance training, Resistance Training, Testosterone, Estradiol
Keikha, N, Ayatollahi Mousavi, Sa, Nakhaei, Ar, Amanloo, S, Shahidi, Gh, Amiri, S,
Volume 9, Issue 1 (March, April[PERSIAN] 2015)
Abstract
Abstract
Background and Objective: Dermatophytes are the fungi that have the ability to attack the keratinized tissues such as the skin, hair and nails. Infections caused by these organisms are named dermatophytosis. We aimed to compare Minimum inhibitory concentration (MIC) of Crude extracts of Active Actinomycete Isolates with Terbinafine, Griseofulvin, Ketoconazole and Fluconazole Drugs against Microsporum Canis, Microsporum gypseum and Trichophyton mentagrophytes.
Material and Methods: In this experimental study, in order to find MIC by actionmycete, 100 isolates were studied and then crude extracts of the active actinomycete isolates were prepared in sterile conditions. Finally, the crude extracts obtained at different concentrations were used to obtain the MIC of Microsporum Canis, Microsporum gypseum and Trichophyton mentagrophytes. Moreover, various concentrations of the drugs such as terbinafine, griseofulvin, ketoconazole and fluconazole in solvent Dimethyl sulfoxide (DMSO) were prepared and their growth inhibitory effect was evaluated and then compared with the results obtained from the crude extract of active actinomycete isolates.
Results: the crude extracts obtained from active Actioiomycetes isolates and the drugs such as terbinafine, griseofulvin, ketoconazole and fluconazole, in a dose-dependent manner, could inhibit the growth of Microsporum Canis, Microsporum gypseum and Trichophyton Mentagrophytes.
Conclusion: compared to MIC of Crude extract of active actinomycete isolates, Terbinafine has a significant effect on the growth inhibition in all of the fungal Dermatophytes and then griseofulvin, ketoconazole and fluconazole are in the next rank, respectively.
Keywords: Actinomycetes Crude Extract, Microsporum Canis, Microsporum Gypseum, Terbinafine
Ameri, E. (bsc), Saeedi, P. (phd), Aa Ayatollahi,
Volume 9, Issue 1 (March, April[PERSIAN] 2015)
Abstract
Abstract
Background and Objective: Efficient human resource is the major advantage of an organization over others. Commitment to organization not only may reduce sick leave, delays and displacements but also give rise to a significant increase in productivity, more vitality among staff, better attainment of the organizations' goals and personal aims. This study aimed to evaluate the relationship between personal characteristics and organizational commitment among medical laboratory staff.
Material and Methods: This correlational study was conducted on 105 medical laboratory staff selected randomly in Gorgan, 2010-2011. The instruments for data collection were NEO personality inventory and Meyer and Allen's model of organizational commitment.
Results: The relationship between organizational commitment and the variables such as neuroticism, openness, agreeableness and Conscientiousness was positively significant but that was not the case for extroversion characteristic.
Conclusion: Given the positive relationship between personality characteristics and organizational commitment, we recommend improving these characteristics to enhance staff commitment to organization.
Keywords: Organizational Commitment, Personality Characteristics, Laboratory Staff
Ayatollahi, Aa, Amini, A, Rahimi, S, Kiaei, M, Koohsar, F, Khandan Del, A,
Volume 9, Issue 2 (may,jun 2015[PERSIAN] 2015)
Abstract
Background and Objective: Nosocomial infection is one of the main factors of mortality in hospitals . One of the most important measures to control infection in hospitals is sampling of equipment and culturing the samples . This study aimed to investigate the prevalence of gram-negative bacilli obtained from the equipment of the hospital wards .
Material and Methods: This Descriptive study was carried out on 488 specimens taken from medical and non-medical devices and equipment of various wards, via census sampling. the samples taken by sterile swabs in Tryptic Soy Broth (TSB) were inoculated in blood agar and Eosin-Methylene Blue agar, and by biochemical standard tests the isolated colonies were identified.
Results: Of 488 isolates, 157 (32.17%) were positive for the presence of gram-negative bacilli. The highest bacterial contamination was related to Enterobacter (37.58%). Of hospital wards, the highest infection related to the surgical wards (19.75%), and the highest contamination is related to laryngoscope blades (12.74%) and ECG sensor device and the monitoring interface (7%).
Conclusion: Microbial infection with gram-negative bacilli is an overwhelming condition in hospital equipment.
Key Words: Gram Negative Bacilli, Nosocomial Infection, hospital wards, hospital equipments, Gorgan
Hami Kaboosi , Abolfazl Khandan Del , Ezzat Allah Ghaemi , Sepide Bakhshande Nosrat, Ali Asghar Ayatollahi , Nastaran Golriz ,
Volume 10, Issue 2 (Mar,Apr2016 2016)
Abstract
ABSTRACT
Background and Objective: Staphylococcus aureus is the most common and important infectious agent. This bacterium can enter the bloodstream and cause some complications in the intensive care unit (ICU).This organism can frequently be found in the nose and transmitted by the carriers. This study aimed to determine the efficiency of eradicating S. aureus from the nose of ICU personnel in reducing the risk of S. aureus infections in the Panje Azar Hospital in Gorgan, Iran.
Methods: Sampling was done using sterile swabs collected from the anterior nasal passages.All samples containing Gram-positive cocci were sent to the laboratory of Faculty of Medicine for identification and evaluation of methicillin resistance. All S. aureus nasal carriers were treated with mupirocin ointment b.d for 5 days. The Samples were cultured again after five weeks to evaluate the eradication of S. auerus from the nose of subjects.
Results: Overall, seven ICU personnel (11.7%) were S. aureus carriers. Two isolates (3.3%) were found as methicillin resistant using both methods of disc diffusion and PCR. The frequency distribution of positive cases indicated a significant difference in terms of work experience (P = 0.012).
Conclusion: The findings show that treatment of carriers with 2% mupirocin topical ointment eradicates S. aureus from the nose. No S. aureus isolates was found in reculture of nasal samples. Treatment of healthy carriers can significantly reduce the risk of infections caused by the bacterium in the ICU.
Sanaz Salar Amoli, Sima Besharat, Amir Nader Emami Razavi, Aliasghar Ayatollahi, Hamidreza Joshaghani,
Volume 13, Issue 1 (Jan-Feb 2019)
Abstract
Background and Objective: HER-2 (human epidermal growth factor receptor 2) is one such gene that can play a role in the development of breast cancer by making HER-2 proteins (receptorson breast cells). Normally, HER-2 receptors control breast cells grow and Division. HER-2 protein over expression is the cause of up to 20% of breast cancers. The phosphoinositide 3 kinase (PI3K) pathway is important in the oncogenic function of HER-2.
It has been reported compounds including Se, such as selenite significantly attenuated oxidative-stress-induced activation of the PI3K signaling pathways and can exhibit antitumor activity by downregulating PI3K activation.
In this study, we evaluated Association of tissue selenium level and Human epidermal growth factor receptor 2 (HER-2) expression in breast cancer.
methods:
Se contents and expression of HER-2 were determined in 30 tissue collected from 30 women diagnosed with breast cancer based on immunohistochemistry (HER-2) and atomic absorption (Se).
Results:
About 30% of the samples were positive for HER-2 expression. Mean level of tissue selenium in tumors for positive and negative HER-2 was 268.15 µg/l and 206.43µg/l respectively. So, there was no significant association between selenium level and HER-2 expression. (p>0.005)
Conclusion:
There is no Association of tissue selenium level and HER-2 expression in breast cancer.
Keyword:
Selenium, HER-2, breast cancer
Ali Asghar Ayatollahi, Abolfazl Khandan Del, Ailar Jamalli, Khashayar Shahin, Ania Ahani Azari,
Volume 14, Issue 1 (Jan-Feb 2020)
Abstract
Background and objectives: Staphylococcus aureus is a frequent cause of hospital- and community-associated infections on a global scale. This organism is responsible for causing an extensive range of diseases and many of them are capable of biofilm formation for their survival. By this method, treatment of them with antibiotics become very difficult and antibiotic resistance is another rising concern.
Material and Methods: The clinical samples were collected and examined for Staphylococcus aureus by microbiological and biochemical tests. Then, the biofilm formation in Staphylococcus aureus isolates was detected by microtiter plate. Using SYBR Green Real-Time PCR, the expression of PSM was determined.
Results: A total of 60 strains of Staphylococcus aureus were isolated from clinical isolates. Of them, 47 strains (78.3%) were identified biofilm producing and the others were considered negative for biofilm formation. After real-time PCR testing to detect PSM, it was determined that 100% of the strains were positive for biofilms and PSM genes. The results of phenotypic and genotypic tests of biofilm were closely related to each other and the expression of PSM B gene was 80%. It was found that 100% of strains were biofilm producing and PSM B gene was present in 78.3% (47 strains) of them.
Conclusion: The prevalence of biofilm production in Staphylococcus aureus strains isolated from clinical samples was high, so it is highly important to monitor the prevalence of these organisms in hospitals and community as well as their antimicrobial resistance.
Alireza Ahmadi, Mahdi Ghasemian , Ali Asghar Ayatollahi, Murtadha Al-Khabori, Seyedeh Somayeh Hosseini Alarzi, Mohammad Taher Hojjati,
Volume 15, Issue 5 (Sep-Oct 2021)
Abstract
Background and objectives: Diagnosis glucose intolerance in pregnancy is very important in preventing maternal and fetal complications. In this study, we compared hematological and biochemical characteristics of healthy pregnant women and women with gestational diabetes mellitus (GDM) to find predisposing and prognostic variables of GDM.
Methods: In this study, 80 pregnant women (at 24-28 weeks of pregnancy) were divided into a GDM group and non-GDM group by performing oral glucose tolerance test using 75 g glucose according to the International Association of the Diabetes and Pregnancy Study Groups criteria.
Results: The mean age of women with GDM was significantly higher than those without GDM (p=0.048). Other variables including body mass index, gestational age and daily sleep duration did not differ significantly between the two groups (P>0.05). There was a significant association between family history of diabetes and incidence of GDM (p=0.040). In addition, the C-peptide level was significantly higher in pregnant women with GDM (p=0.004).
Conclusion: Considering the role of C-peptide in predicting metabolic syndrome, it is suggested to use this factor for identification of GDM patients.
Sepideh Shakeri, Narjes Soltani, Mohammad Reza Javan, Mehrnaz Abdolalian, Hossein Ayatollahi, Seyyede Fatemeh Shams,
Volume 17, Issue 1 (Jan-Feb 2023)
Abstract
Background and objectives: Fanconi anemia (FA) is an autosomal recessive disorder that usually manifest in forms of pancytopenia, hyperpigmentation, and skeletal complications. Mutation in the DNA repair regulatory genes is associated with the development of FA. Examination of chromosomal breakages when chromosomes are exposed to cross-linking agents is a common method of FA diagnosis. This study aimed to evaluate the prevalence and characteristics of patients with FA in Mashhad, northeast of Iran.
Methods: In this study, we evaluated 312 suspected FA patients who had been referred to the laboratory of Ghaem Hospital during 2014-2020. The mitomycin C method was used to identify FA-positive subjects.
Results: After the examinations, 84 patients (26.9%) were cytogenetically positive for FA. Of 84 patients, 48 (57.1%) were male and 36 (42.9%) were female. Thumb abnormality was the most common congenital anomaly (43.2%).
Conclusion: Based on the findings, males are more susceptible to FA, and thumb abnormality is the most common congenital anomaly associated with FA. Combination of clinical manifestations and genetic susceptibility in patients may contribute to a more accurate diagnosis.
