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Volume 15, Issue 6 (Special issue (Nov-Dec) 2021)
mljgoums 2021, 15(6): 52-57 |
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Hosseini M, Hasannejad-Bibalan M, Yaghoubi T, Mobayen M, Khoshdoz P, Khoshdoz S, et al . Prevalence and Antibiotic Resistance Pattern of Gram-Positive Isolates from Burn Patients in Velayat Burn Center in Rasht, North of Iran. mljgoums 2021; 15 (6) :52-57
URL: http://mlj.goums.ac.ir/article-1-1408-en.html
URL: http://mlj.goums.ac.ir/article-1-1408-en.html
Mobina Hosseini1 
, Meysam Hasannejad-Bibalan2 , Tofigh Yaghoubi1 , Mohammadreza Mobayen3 , Parisa Khoshdoz1 , Sara Khoshdoz1 , Niloofar Faraji1 , Hadi Sedigh Ebrahim-Saraie 4
, Meysam Hasannejad-Bibalan2 , Tofigh Yaghoubi1 , Mohammadreza Mobayen3 , Parisa Khoshdoz1 , Sara Khoshdoz1 , Niloofar Faraji1 , Hadi Sedigh Ebrahim-Saraie 4
1- Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
2- Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
3- Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran
4- Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran , seddigh.hadi@gmail.com
2- Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
3- Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran
4- Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran , seddigh.hadi@gmail.com
Abstract: (1807 Views)
Background and objectives: Bacterial contamination of wounds is a serious problem, particularly in burn patients. Gram-positive bacteria are the predominant cause of infection in newly hospitalized burn cases. This study aimed to survey the prevalence and antibiotic resistance pattern of gram-positive bacterial isolates among burn patients in Rasht, North of Iran.
Methods: This cross-sectional study was conducted on burn patients with a positive culture for gram-positive isolates who were hospitalized in the Velayat Burn Center in Rasht, North of Iran, during 2017-2020. The isolates were identified using standard microbiological methods. Moreover, the antibiotic resistance pattern was determined by the disk diffusion method.
Results: During the study period, 671 bacterial cultures were obtained, of which a total of 16 gram-positive isolates were taken from the patients. The frequency of coagulase-negative staphylococci (CoNS), Staphylococcus aureus, and Enterococcus spp. was 68.7%, 18.8%, and 12.5%, respectively. In addition, the highest rate of resistance in CoNS isolates was against trimethoprim/sulfamethoxazole. The highest rate of resistant among S. aureus isolates was recorded against penicillin. Moreover, Enterococcus faecalis isolates showed a high level of resistance to ampicillin, erythromycin, tetracycline, gentamicin, and ciprofloxacin. All isolates were susceptible to teicoplanin. Moreover, the frequency of methicillin-resistant S. aureus isolates was 66.7%.
Conclusion: Given the increasing prevalence of drug-resistant strains, especially in susceptible burn patients, it is imperative to analyze the bacterial etiology of nosocomial infections periodically and epidemiologically.
Methods: This cross-sectional study was conducted on burn patients with a positive culture for gram-positive isolates who were hospitalized in the Velayat Burn Center in Rasht, North of Iran, during 2017-2020. The isolates were identified using standard microbiological methods. Moreover, the antibiotic resistance pattern was determined by the disk diffusion method.
Results: During the study period, 671 bacterial cultures were obtained, of which a total of 16 gram-positive isolates were taken from the patients. The frequency of coagulase-negative staphylococci (CoNS), Staphylococcus aureus, and Enterococcus spp. was 68.7%, 18.8%, and 12.5%, respectively. In addition, the highest rate of resistance in CoNS isolates was against trimethoprim/sulfamethoxazole. The highest rate of resistant among S. aureus isolates was recorded against penicillin. Moreover, Enterococcus faecalis isolates showed a high level of resistance to ampicillin, erythromycin, tetracycline, gentamicin, and ciprofloxacin. All isolates were susceptible to teicoplanin. Moreover, the frequency of methicillin-resistant S. aureus isolates was 66.7%.
Conclusion: Given the increasing prevalence of drug-resistant strains, especially in susceptible burn patients, it is imperative to analyze the bacterial etiology of nosocomial infections periodically and epidemiologically.
Keywords: Staphylococcus aureus [MeSH], Enterococcus [MeSH], Burns [MeSH], Gram-positive bacterial infections [MeSH]
Research Article: Original Paper |
Subject:
Microbiology
Received: 2021/07/21 | Accepted: 2021/09/8 | Published: 2021/10/18 | ePublished: 2021/10/18
Received: 2021/07/21 | Accepted: 2021/09/8 | Published: 2021/10/18 | ePublished: 2021/10/18
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