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Streptococcal pharyngitis and rheumatic fever/rheumatic heart disease are among the major public health problems in children. In this study we assay the frequency of group A Beta hemolytic Streptococcus in nasopharynex of 1588 healthy 6-12 years children in Gorgan in north of Iran. The sample obtained during February to March 1998, using sterile soap. The prevalence of this bacteria were 11% (175 strains) the rate of colonization in girls and boys were 10.8 and 11.2% respectively. Our study shows that the carrier of this bacteria in Town’s school children are more than the villages.

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Golden Staphylococci is one of the most common factors in skin and systemic infection. About 30% of people are carrying this bacterium in their skin and nose. Increased drug resistance in this microorganism and consequent infection, has gained the attention of scientific organization. Therefore we decided to determine the prevalence of nose carrier of this bacterium in healthy children in Gorgan schools. During the winter 1998 to March 1999 the sample has been taken from 1193 student’s nose with sterile cotton swab. These results showed that in 194 samples (16.3%) Staphylococci Aureus has been isolated, from these samples 114 cases belong to girls (16.1%) and 80 cases were boys (16.4%) that there is not a meaningful variation between them. The number of bacteria isolated from the villages children was 109 cases (17.6%) and in town’s children were 85 cases (14.8%), also this difference didn’t show significant difference. The prevalence of carrier among the 6-12 years old was 12-25.3%, which has got a significant meaning (P<0.001). Antibiotic resistance in the isolated S.aureus were tested and result showed that 34.8% of samples are resistant to Methicilin and 1.7% were resistant to Vancomycin, only 4% were sensitive to Penicillin. Therefore with regard to the results of this investigation, further researches are recommended in relation between strain’s of S.aureus that isolated from carrier’s and strain’s that isolated from patients and to determine their drug resistance in this region.

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Background and Objective: Neisseria meningitidis is an obligate pathogen of human and temporary colonizes the mucosa of upper respiratory tract. This study was done to determine the frequency of pharyngeal Neisseria Carriage among 10-12 years old pupiles. Materials and Methods: This cross sectional study was carried out on 364 pupiles at four primary schools in Tehran during spring 2008 and winter 2009. The samples were collected from pharyngeal region and were cultured on Thayer-Martin Agar. Results: Among 364 collected samples from pharynx of pupiles, Neisseria meningitidis not found on the selective media, but three of pupiles were carrier of Neisseria lactamica. Conclusion: This study showed that Neisseria meningitides colonization was not observed in the pharynx of 10-12 years old pupiles.