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:: Search published articles ::
Showing 4 results for Histopathology

Azarhoosh R (md), Golalipour Mj (phd), Behnampour N (msc), Basharkhah A (md),
Volume 1, Issue 3 (10-1999)
Abstract

Breast cancer is the most common cancer in women. Histologic grading is one of the prognostic factors in breast cancer. The present study performed in analytic descriptive method and based on the slide review of beast biopsies received in the pathology department of 5th Azar Hospital from 1976 to 1978, and on the basis of Bloom-Richardson criteria (Mitoses, tubule formation and nuclear pleomorphism). The results are consist of: 1) Infiltrating duct carcinoma is the most common histopathologic form, and tubular carcinoma is the least common 2) The most common age is 36-45 years 3) There is meaningful relationship between mitoses and tubule formation and between pleomorphism and tubule formation. But there is no relation between nuclear pleomorphism and tubule formation in the tumor. Histologic grading of breast carcinoma should be reported by pathologist for clear determination of prognosis and also the best choice for management of the tumors.
Soltani B (md), Azarhoosh R (md),
Volume 1, Issue 3 (10-1999)
Abstract

Pseudoxantoma Elasticum is a hereditary disease with prevalency of 1 among 160000 people in which yellowish papules and plaques are symmetrically distributed in abnormally lax skin of the neck, axilla, groin, and cubital and popliteal spaces, other parts of the body are less frequently involved. Patient that has been presented is 30 years old Turkman woman referred to 5th Azar Hospital with skin problems contains skin folds at neck, yellowish papules at ant, abdomen, cubital area and neck. After skin biopsy, histopathological findings confirmed clinical diagnosis of Pseudoxantoma Elasticum.
Khayatzadeh J, Afshar M, Moallem Sa, Shahsavan M, Naseh Gh,
Volume 13, Issue 1 (3-2011)
Abstract

Background and Objective: The food additives, like sodium and potassium benzoate are used in many food products and drugs to prevent the growth of yeast and molds. There is no report about the histopathological effect of potassium benzoate. Placenta, has a critical role in embryonic development therefore this study was set up to evaluate the effects of potassium benzoate on placenta of BALB/c mice.

Materials and Methods: 45 BALB/c female mice were allocated into two experimental (1, 2) and one control groups. Experimental groups received daily intraperitoneal injection of 280 and 560 mg/kg/body weight of potassium benzoate and control group received normal saline. All injections were done during 10 days before mating and 5th to 16th of gestational days (GD). In GD 18 all placenta were removed via cesarean section. Macroscopic studies for morphological abnormalities were done and after measuring of placental weight and diameter, for microscopic studies the specimens were fixed and tissue passage were done. Tissue sections were stained with hematoxylin-eosin and histopathological changes were studied. Weight, diameter and percentage of agenesis of placenta in all groups were gathered. Data analyzed with using
SPSS-11.5, ANOVA and Tukey tests.

Results: The mean weight and diameter of the placenta in both experimental groups 1 and 2 were significantly decreased compared to control group. Also atrophy of placenta in the experimental groups was increased significantly compared to the control group (P<0.05). Comparison of weight and diameter between groups 1 and 2 was not significant. Percentage of placenta agenesis in the experimental groups was increased significantly compared to the control group (P<0.05). Massive hemorrhage in labyrinth zone, fetal and maternal zones were seen in both experimental groups.

Conclusion: This study showed that exposure of potassium benzoate during mice pregnancy cause morphological and histopathological changes of placenta, including decrease of weight and diameter, agenesis, hemorrhage and tissue disorders.


Ezzeddini R, Gasemi B, Ghojazaded M, Darabi M,
Volume 15, Issue 2 (7-2013)
Abstract

Background and Objective: There is not a general protocol strategy about the necessity of routine microscopic examination of tonsillar samples in children. This study was conducted to determine the histopathological characteristic of tonsillar tissue in 1250 children, Tabriz-Iran. Materials and Methods: This descriptive study was conducted on 1250 children (724 male and 526 female) aged 2-14 years old who underwent tonsillectomy in Tabriz, Iran during 2008-11. Variables including age, sex, clinical diagnosis and surgical indications were recorded. Paraffin blocks were prepared from samples of tonsillectomy and stained with haematoxylin and eosin. Histopathologocal results were categorized in four groups: Follicular hyperplasia, follicular hyperplasia with infection, malignancy and normal. Results: None of the children had initial clinical suspicion of tonsil tumor. Patients’ primary complaints were as follows: 92.5% mouth breathing, 93% nocturnal snoring, 74.3% recurrent and chronic cold and infections, 56.4% sore throat, 48.2% halitosis, 26% nocturnal apnea, 22.2% dysphasia, and 18.2% anorexia. Children with tonsillar hypertrophy and obstructive symptoms (57%), and tonsillar hypertrophy and recurrent infections (42.2%) underwent tonsillectomy. In the histopathlogical examination of all patients being hyperplasia together with lymphoid hypertrophy were observed and there was no evidence of malignancy in any of the patients. Conclusion: No instance of malignancy was found in the histopathological examination of children’s tonsil-removed tissues and all of the tonsils had benign hyperplasia with lymphoid hypertrophy.

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مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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