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Showing 175 results for Reza
Firoozeh Derakhshanpour , Leila Kashani , Shiva Rezaian Deloii , Najmeh Shahini , Seiedeh Maryam Hasheminasab , Volume 24, Issue 1 (3-2022)
Abstract
Background and Objective: Near to 30% of women experience some type of anxiety disorder in their life, which this anxiety occurs more often in pregnancy and after delivery. Maternal anxiety reduces secretion of oxytocin and lactation. On the other side, the level of maternal stress and anxiety increasingly increases the incidence of postpartum. This study was carried out to evaluate the prevalence of postpartum anxiety in Gorgan north of Iran during 2018.
Methods: This descriptive-analytical study was performed on 154 women between 15-45 years old and it has passed at least one week to maximum six weeks since their delivery whom referred to obstetrics clinic of Shahid Sayyad Shirazi hospital in Gorgan, North of Iran during 2018. Demographic check list was used to collect the demographic. Data and Spielberg anxiety scale was used to measure anxiety.
Results: Anxiety disorders after childbirth was 41.99%. The overt anxiety score of postpartum women in severe, moderate, mild and little or none level was 8.4%, 44.2%, 27.9%, 19.5%, respectively. The hidden anxiety score of postpartum women in severe, moderate, mild and little or none level was 9.7%, 48.1%, 24.7%, 17.5%, respectively. The overt anxiety score in employee mothers was significantly higher than housewive mothers (P<0.05). The overt anxiety score in women with marital discord was significantly higher than in women without marital discord (P<0.05). Ther was not significant relationship beween overt and hidden anxiety score with the type of delivery, mother's education, mother's residency and familial income.
Conclusion: The prevalency of postpartum anxiety disorders was high in this region and it was related to job and marital discord.
Ahmad Reza Yousef Pour Dehaghani , Farhad Pashazadeh , Morteza Naji, Volume 24, Issue 1 (3-2022)
Abstract
Background and Objective: Having a proper diet is very important. Many risk factors are involved in the development of cardiovascular disease that by changing them, the incidence of this disease can be reduced. This study was performed to determine the relationship between nutritional knowledge and level of physical activity with the prevalence of metabolic syndrome and some cardiovascular risk factors in militaries men.
Methods: This descriptive-analytical study was performed on 97 athletes and non-athletes militaries men. The standard Parmenter and Wardle Nutrition Knowledge Questionnaire of 1999 and Baecke Physical Activity Questionnaire were completed. Subjects' fitness scores and physical indicators were measured. Prevalence of metabolic syndrome, based on revised ATP ш and IDF was calculated.
Results: The mean nutritional knowledge of the subjects was moderate to low. There was a significant correlation between the nutritional knowledge, level of physical activity and fitness score and cardiovascular risk factors (P<0.05). Also there was a significant correlation between the nutritional knowledge, level of physical activity and fitness score with preventing metabolic syndrome (P<0.05).
Conclusion: With increasing nutritional knowledge, physical activity and fitness scores the risk of cardiovascular factors reduces and the possibility of metabolic syndrome prevention increase.
Mohammad Mehdi Soltan Dallal , Mohammad Kazem Sharifi Yazdi , Alireza Monadi Sefidan , Gholamreza Hassanpour , Sara Sharifi Yazdi, Shabnam Haghighat Khajavi , Saeed Vahedi , Seyedeh Masoomeh Abrichamchian Langaroudi , Mahdieh Pourmoradian , Hedroosha Molla Agha Mirzaei , Volume 24, Issue 1 (3-2022)
Abstract
Background and Objective: Yersinia is water and foodborne organism that cause human gastroenteritis. This study was done to evaluate the frequency of Yersinia species isolated from children diarrheal samples and chicken meat in Tehran, Iran.
Methods: In this descriptive study 250 sample of diarrhea of children referred to the Children's Medical Center, Tehran, Iran and 250 samples of chicken were collected and examined for Yersinia infection during July 2016 to March 2017. Isolation method was performed based on initial enrichment in phosphate buffer for 3 weeks in refrigerator (cooling in c4 +) and then using KOH as secondary enrichment and culture on CIN agar medium. Biotyping method was used to determine pathogenic strains.
Results: In this study, 5(2%) isolates from pediatric diarrhea samples and 20 isolates (8%) from chicken meat samples were obtained from Yersiniaenterocolitica. Biotyping of human Yersiniaenterocolitica isolates identified 3 cases of biotype 1A, one case of biotype 1B, one case of biotype 2 and from chicken meat isolates, 16 isolates belonged to biotype 1A and 4 isolates belonged to biotype 1B.
Conclusion: Presence of common pathogenic 1B and non-pathogenic 1A biotypes in pediatric diarrhea samples and chicken meat can indicate the cause of diarrhea in children.
Afshin Naghizadeh , Mehran Zarghami , Ensiyeh Babaie , Hoda Rezaei Roshan , Habibolah Khazaie , Mojtaba Yassini Ardekani , Nour Mohammad Bakhshani , Ali Sahraian , Majid Torabi Yingjeh , Seyed Ataullah Aghilian , Volume 24, Issue 2 (7-2022)
Abstract
Background and Objective: Most people who commit suicide suffer from psychiatric disorders, especially depression and substance-related disorders. However, major psychiatric disorders are not the sole risk factor for suicide, and other reasons, such as physical illness, may also be considered as an important factor for suicide ideation. This study was conducted to investigate the prevalence of suicidal ideation and its relationship with depression and the general health status of patients referred to addiction treatment centers in Iran.
Methods: This descriptive-analytical study was conducted on 689 patients referred to addiction treatment centers in Yazd, Khorasan Razavi, Mazandaran, Sistan and Baluchistan, Fars, East Azarbaijan, and Kermanshah Provinces who were undergoing maintenance treatment with methadone in 2017. In this multicenter study, the subjects were selected by two-stage sampling; in the first stage, seven provinces (clusters) were randomly selected, and in the second stage, the patients from the selected provinces were enrolled via convenience sampling. The instruments used in this study included the General Health Questionnaire, the Beck Depression Inventory, and the Beck Suicide Idea Scale.
Results: Of 689 patients, 218 (31.6%) had suicidal ideation. 21.91% (151 cases) of subjects had history of attempted to suicide. There was a significant relationship between suicidal ideation, depression, and general health status and its dimensions including physical symptoms, anxiety and sleep disorders, social functioning, and depression (P<0.05).
Conclusion: Suicidal ideation is present in one-third of the people who refer to addiction treatment centers in Iran. Depression and poor general health are major contributors to suicidal ideation.
Samira Eshghinia , Seyyede Arefe Mirsoleimani Azizi , Erfan Rezaie Shirazi , Roghieh Golsha , Volume 24, Issue 2 (7-2022)
Abstract
Background and Objective: Hemoptysis is defined as the expectoration of blood from the lower respiratory tract. Bronchiolitis, bronchogenic carcinoma, and bronchiectasis are the most common causes of hemoptysis in developed countries, while infections caused by Mycobacterium tuberculosis are the most common cause in endemic countries. This study was conducted to determine the frequency of causes of hemoptysis and some related factors.
Methods: This descriptive-analytical study was done on 68 patients (37 men and 31 women, average age 56.85±17.27 years) who were referred to the Shahid Sayyad Shirazi Hospital in Gorgan, north of Iran during 2014-16 with the complaint of hemoptysis. Demographic information, cause of hemoptysis and history of illness or drug abuse were extracted from the patients’ records.
Results: Based on the results, 42.6%, 45.6%, and 17.6% of the patients had a history of smoking, drug abuse, and diabetes, respectively. The most frequent causes of hemoptysis were bronchiectasis (25%), pneumonia (20.6%), tuberculosis, and lung cancer (16.4%). Gender was determined as an independent risk factor for hemoptysis (P<0.05). The most common causes of hemoptysis were bronchiectasis, lung cancer and pneumonia in men, and tuberculosis and bronchiectasis in women. Age, drug abuse, smoking, and diabetes had no significant association with the occurrence of hemoptysis.
Conclusion: Bronchiectasis, tuberculosis, and lung cancer are the main causes of hemoptysis, and gender is an independent risk factor for hemoptysis in the study area.
Ammar Raoufi Sangachin, Ahmad Abdi, Alireza Barari , Volume 24, Issue 2 (7-2022)
Abstract
Background and Objective: Aging and old age are associated with an increase in inflammatory cytokines. Due to their anti-inflammatory properties, constituents of spirulina may be able to reduce or even improve this process. This study was performed to determine the effects of endurance training and spirulina supplementation on the level of inflammatory cytokines in overweight men.
Methods: In this clinical trial, 40 overweight, middle-aged and elderly men were randomly selected and divided into 5 groups: control-normal, control-overweight, overweight + training, overweight + supplement, and overweight + training + supplement. The training program consisting of an hour of walking on a treadmill, stationary bike workout, and climbing stairs was performed at an intensity of 65% of the maximum heart rate, 3 sessions a week, for 8 weeks. Individuals in the supplement groups received a spirulina tablet (500 mg) twice daily in the morning and evening. Blood sampling was performed after 12 hours of fasting at baseline and 48 hours after the last training session. The level of inflammatory cytokines including transforming growth factor-beta (TGF-β), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) was measured by enzyme-linked immunosorbent assay.
Results: The levels of TGF-β, IL-6, and TNF-α were higher in the control-overweight group than in the healthy control-normal group (P<0.05). Training and supplementation significantly reduced the inflammatory markers in overweight men (P<0.05). Moreover, the level of inflammatory markers was significantly lower in the training + supplement group compared with the training group and the supplement group (P<0.05).
Conclusion: Endurance training combined with spirulina supplementation can significantly reduce inflammatory factors in overweight individuals.
Sayyed Gholamreza Mortazavi Moghaddam , Asghar Zarban , Ali Mirshahi , Volume 24, Issue 3 (10-2022)
Abstract
Background and Objective: Asthma is a chronic airway disorder with a rising prevalence. Dietary factors, antioxidant indicators and vitamin D deficiency are associated with the disease. Due to the presence of receptors for this vitamin in the lung, this study aimed to investigate the effects of vitamin D administration on lung function, serum immunoglobulin E (IgE) level and total serum antioxidant activity in patients with moderate to severe asthma.
Methods: In this clinical trial, 60 patients with asthma were randomly divided into two groups: a control group (placebo recipient) and an intervention group (recipient of 2,000 vitamin D capsules for 12 weeks). At the beginning and at the end of the study, 5 cc blood samples were taken from each patient, and spirometry test was performed. Total antioxidant capacity (TAC), IgE and vitamin D parameters were measured.
Results: The mean score of forced expiratory volume (FEV1) and FEV1/FVC in both groups as well as the mean FVC in the control group did not change significantly after the intervention. The mean FVC score, vitamin D level and TAC in the intervention group increased significantly after the intervention, while the IgE levels reduced significantly.
Conclusion: Taking vitamin D tablets could increase the antioxidant parameters in asthmatic patients.
Ali Ghafari , Fatemeh Zahra Gharib , Alireza Yousefi , Volume 24, Issue 3 (10-2022)
Abstract
Background and Objective: Dogs are associated with more than 60 types of common diseases with humans, among which parasitic diseases play an important role in public health. This study aimed to estimate the frequency of gastrointestinal helminths fauna among dogs in Gorgan, Iran.
Methods: This descriptive-analytical study was done on 70 dogs (37 male and 33 female) consisting of 40 shelter dogs, 18 pet dogs and 14 guard dogs in Gorgan (Iran) from November 2019 to January 2020. Age, gender and housing places of the dogs were recorded, and dogs' fecal samples were examined for gastrointestinal helminths by flotation method with Sheather's solution.
Results: The eggs of gastrointestinal helminths were detected in 41 dogs (58.6%), including Toxocara canis (29.3%), Echino-taenia (26.8%), hookworms (24.4%), Trichuris vulpis (7.3%) and Toxascaris leonina (12.2%). The highest and lowest rates of infection were related to Toxocara canis (31.8%) in female dogs Trichuris vulpis (5.3%) in male dogs, respectively. Also, in female dogs, 69.7% of the samples were infected with at least one gastrointestinal parasite, and there was a significant relationship between parasitic disease and female gender (P<0.05). Also, the highest infection rate was observed in shelter dogs (61%).
Conclusion: The frequency of gastrointestinal helminths among dogs in Gorgan is high, particularly among female dogs.
Masoomeh Rezanezhadi , Hamid Reza Joshagani , Volume 24, Issue 4 (12-2022)
Abstract
Background and Objective: Gene mutations leading to thrombophilic disorders and changes in blood coagulation factors during pregnancy play an important role in the occurrence of recurrent abortions. This study was conducted to determine the relationship between polymorphism of thrombophilic genes and coagulation factors in women with recurrent miscarriage.
Methods: In this descriptive-analytical study, 29 women with a history of recurrent abortions (at least three times) were investigated. Demographic data were collected. Total genomic DNA was isolated from peripheral blood. The presence or absence of mutation in factor II (G20210A), factor V Leiden (G1691A), factor V HR2 (H1299R), MTHFR C677T, and MTHFR A1298C polymorphisms were assessed by PCR.
Results: Coagulation factors and thrombophilic mutations had no significant association with recurrent miscarriage.
Conclusion: The results obtained in this study showed that none of the studied polymorphisms could justify frequent abortions in women. Therefore, it is suggested to evaluate genetic factors in normal individuals or immediate and extended family of the study population with no miscarriage history.
Mahdi Vahidbalan , Mohammadreza Nasirzadeh , Volume 24, Issue 4 (12-2022)
Abstract
Background and Objective: Vincristine is an important anticancer drug, which is highly toxic to the liver. It is a naturally occurring polyphenol found in many plants. Some studies have shown the anti-inflammatory and antioxidant effects of resveratrol. This study was conducted to determine the hepatoprotective and antioxidant effects of resveratrol against vincristine-induced toxicity in mice.
Methods: In this experimental study, 32 female NMRI mice weighing 25-30 grams were randomly divided into four groups (n=8): control, vincristine, vincristine + resveratrol, and resveratrol. The animals received vincristine intraperitoneally at a dose of 3 mg/kg/bw once a week for four weeks. They also received resveratrol at a dose of 30 mg/kg for 28 days through gastric gavage. At the end of the study, the activity of alanine transaminase (ALT) and aspartate transaminase (AST) were measured. The level of antioxidant enzymes including superoxide dismutase (SOD), glutathione peroxidase (GPX), malondialdehyde (MDA) as well as total antioxidant capacity (TAC) was measured in the liver tissue of mice.
Results: The activities of ALT, AST, SOD, and GPX decreased in the vincristine group compared to the control group, while MDA level increased significantly (P˂0.05). Treatment with resveratrol in the vincristine + resveratrol group improved the evaluated parameters compared to the vincristine group (P˂0.05).
Conclusion: Resveratrol has protective and antioxidant effects against vincristine-induced oxidative damage in the liver of mice.
Ebrahim Piri , Mohsen Barghamadi , Reza Farzizade , Volume 24, Issue 4 (12-2022)
Abstract
Background and Objective: The ankle is one of the most vulnerable joints in the body in terms of weight bearing. The pronate foot is the most common complication of the lower limbs that causes a decrease in the height of the internal longitudinal arch when bearing body weight. This study was conducted to compare the effect of exercises in water and with thera-band on loading rate, impulse, and free torque in people with pronation immediately and after eight weeks.
Methods: This clinical trial was conducted on 45 male students with pronate foot at the University of Mohaghegh Ardabili. The subjects were randomly divided into three groups of 15 people including control, thera-band, and water training. The intervention groups performed the exercises for eight weeks and the immediate and long-term effects of the exercises were compared.
Results: The positive and negative peaks of free torque, vertical loading rate, and vertical impulse in the water training group after eight weeks decreased significantly compared to the pretest and immediately after exercise (P<0.05). Also, the internal-external direct impulse in the water training group increased significantly after eight weeks compared to the pretest and immediately after exercise (P<0.05). In addition, the positive peak of free torque and vertical impulse decreased significantly in the thera-band group after eight weeks compared to the pretest and immediately after exercise (P<0.05). Moreover, the loading rate decreased significantly immediately and after eight weeks in the thera-band group compared to the pretest (P<0.05).
Conclusion: Eight weeks of exercise in water and with thera-band can improve loading rate, free torque, and impulse in people with pronate foot during walking.
Ali Vafaei , Maryam Bakhtiari , Amir Sam Kianimoghadam , Booshra Shirzad , Mohammad Reza Sadeghi , Nima Hajitabar Firouzjaei, Volume 25, Issue 1 (3-2023)
Abstract
Background and Objective: With the increase in the spread of COVID-19, mental health consequences such as fear, anxiety, and depression have become prevalent. This study aimed to investigate the predictive role of fear of COVID-19 and quarantine fatigue on depression in congenital heart disease patients during the pandemic.
Methods: This descriptive-analytical study was conducted on 105 patients with congenital heart disease (6 men and 99 women) who were referred to Shahid Rajaee Hospitals and Tehran Heart Center during 2021-22. Data were collected using a depression scale, a fear scale for COVID-19, and a quarantine fatigue questionnaire.
Results: The results showed that 28.6% of patients with congenital heart disease experienced mild depression, while 7.6% had severe depression. Quarantine fatigue was found to be mild in 43.8% of patients. Additionally, fear of COVID-19 (r=0.195, P=0.001) and quarantine fatigue (r=0.617, P=0.001) were significantly correlated with depression in congenital heart patients.
Conclusion: Fear of COVID-19 is related to depression caused by coronavirus and quarantine fatigue in patients with congenital heart disease.
Reyhanesadat Hashemi-Golpayegani , Reza Sedaghat , Narges Haddadzadeh-Niri , Mehrdad Roghani , Volume 25, Issue 1 (3-2023)
Abstract
Background and Objective: Temporal lobe epilepsy is characterized by the degeneration of hippocampal neurons and the sprouting of mossy fibers in the dentate area. This study aimed to investigate the impact of the hydroalcoholic extract of Rosa damascene on hippocampal tissue changes induced by kainic acid-induced epilepsy in rats.
Methods: In this experimental study, 28 male Wistar rats weighing between 185-225 grams were used. The animals were divided into four groups: sham group, sham treated with hydroalcoholic extract, epilepsy (kainic acid), and epilepsy pretreated with hydroalcoholic extract. Kainic acid was used for intra-hippocampal and unilateral injection to induce epilepsy in the animals at 0.8 micrograms per rat. The rats were given 500 mg/kg of the extract intraperitoneally daily for one week before surgery. Five weeks after surgery, thionin and Tim staining methods were performed on the hippocampal slices.
Results: Kainic acid-induced epilepsy resulted in convulsive behavior, and pretreatment with the hydroalcoholic extract significantly reduced the intensity of convulsive attacks (P<0.05). The density of neurons in the CA3 area of the hippocampus in the kainic acid group showed a significant decrease compared to the sham group (P<0.05), while pretreatment with the extract caused a significant increase in the number of neurons in this area compared to the kainic acid group. Additionally, a significant increase in the intensity of mossy fiber sprouting was observed in epileptic rats compared to the sham group, and pretreatment with the extract significantly decreased its intensity (P<0.05).
Conclusion: The pre-treatment with the hydroalcoholic extract of Rosa damascena decreased convulsive behavior, protected hippocampal CA3 neurons and reduced the intensity of sprouting in the hippocampal dentate region in the experimental model of temporal lobe epilepsy induced by kainic acid.
Emad Reza , Hossein Azizi , Volume 25, Issue 1 (3-2023)
Abstract
Background and Objective: Alkaline phosphatase, BMP, and GATA proteins are important factors in the process of spermatogenesis. This study aims to investigate the effect of alkaline phosphatase, GATA, and BMP expression on spermatogenic stem cells, embryonic cells, and embryonic stem-like cells (ES-like) in C57BL mice.
Methods: In this experimental study, spermatogonial stem cells were isolated from three heads of 4-week-old C57BL mice, and embryonic stem cells and ES-like cells were prepared. Alkaline phosphatase staining test was performed on spermatogenic stem cells, embryonic cells, and ES-like cells. The expression of BMP and GATA genes was analyzed using Fluidigm PCR. Protein-protein interaction networks were isolated and drawn using databases.
Results: Positive alkaline phosphatase expression in stem cells and negative expression in testicular Sertoli cells indicated the presence of this enzyme in pluripotent cells. The gene expression of BMP and GATA in spermatogonial stem cells (6.3 and 2.7, respectively), embryonic cells (3.2 and 4.4, respectively), and ES-like cells (8.5 and 2.5, respectively) was positive, but not statistically significant. Bioinformatics studies showed the regulatory role of these genes and their direct effect on alkaline phosphatase.
Conclusion: BMP and GATA genes, along with alkaline phosphatase enzymes, play a crucial role in controlling embryonic and spermatogonial stem cells, maintaining their pluripotency, and guiding them towards differentiated cells.
Keywords:
Yahya Arab Balajelini , Rahmatollah Rezaei , Seyed Mehran Hosseini, Volume 25, Issue 1 (3-2023)
Abstract
Hermaphrodite patients are individuals who, due to various issues such as chromosomal, gonadal or hormonal disorders that occurred during pregnancy, experience physiological abnormalities in their genital area after birth. As a result, they may have both male and female genitalia or be born ambiguously as a baby boy with female sexual organs, or vice versa. In order to study the challenges presented by this condition in the Islamic Penal Code, sources were collected from Irandak, Normagz, and SID Civilica Jihad academic databases using keywords such as hermaphrodite, neutrality, criminal policy, gender identity disorder, gender ambiguity, recidivism, multicrime, neutral jurisprudential rule, and factors that reduce responsibility due to thematic and conceptual relevance. The time frame considered for the study was from 1980 to 2022, and 57 sources were included. The criteria for inclusion in the study were criminal, jurisprudential, and medical articles related to hermaphroditic and criminal topics relevant to the questions posed in the article. The purpose of this study is to provide a correct explanation of the challenges in the Islamic Penal Code and to answer them. Given the nature of these disorders and the lack of knowledge among affected individuals, families, and society, as well as the exclusion of the conditions of these patients in different laws, this article attempts to explain the place of hermaphrodites in medical science, how this disorder occurs in these individuals, and the introduction of hermaphrodite patients in Islamic jurisprudence. It also discusses where these individuals are placed as human beings in Imamiah jurisprudence. The most important part of this article is devoted to the articles of the Islamic Penal Code regarding the commission of crimes such as hudud, retribution, blood money, and punishment. The most significant challenge in implementing penal law for these patients is the lack of differential criminalization. Specifically, there is a need to develop criminal laws for crimes that these individuals are more likely to commit and determine appropriate punishments, such as obtaining a guarantee of non-custodial executions. In addition, during the investigation phase, there is a lack of an appropriate differential procedure for this category of patients. This requires training for judges and officers, such as police and officers dealing with these patients, as well as adaptation of detention spaces (detention centers and prisons) to prevent victimization or re-offending due to the special mental and physical conditions of these patients. In conclusion, research on hermaphrodite patients is necessary to change attitudes towards them and take practical measures at the social level in legislative, judicial and executive criminal policy. This article uses a descriptive method and library sources to explain and analyze this purpose.
Hamidreza Naserpour , Mehdi Khaleghi Tazji , Amir Letafatkar , Hooman Angoorani , Volume 25, Issue 1 (3-2023)
Abstract
Background and Objective: Long-standing groin pain (LSGP) is a common injury in ball games. This study aimed to compare the electrical activity of selected lumbopelvic-hip muscles during a single leg jump-cut maneuver in football players with LSGP and healthy players.
Methods: In this case-control study, 32 football players were divided into two groups: LSGP (n=16) and healthy (n=16). A force plate was used to determine the heel-contact and heel-off moment. The ground reaction forces and the average of three trials of the electrical activity of selected lumbopelvic-hip muscles during a single leg jump-cut maneuver were recorded bilaterally.
Results: At the heel-contact moment, the rectus abdominis and adductor longus muscles on the dominant side and the multifidus muscle on the opposite side showed significantly higher activity in the LSGP group compared to the healthy group (P<0.05). Similarly, at the peak of the vertical reaction force, the rectus abdominis and adductor longus muscles on the dominant side and the multifidus and gluteus medius muscles on the opposite side were significantly more active in the LSGP group (P<0.05). At the toe-off moment, the internal oblique, adductor longus, and gluteus medius muscles on the dominant side and the internal oblique, multifidus, and gluteus medius muscles on the opposite side were also more active in the LSGP group compared to the control group (P<0.05).
Conclusion: Long-standing groin pain causes changes in the electrical activity of muscle groups during different phases of the single-leg jump-cut maneuver, leading to increased dynamic stability and possibly an increased risk of overuse injuries, chronic injuries, economic consequences, and exclusion from sports activities.
Alie Nikdoust , Alireza Dehestani , Reza Shabanian , Minoo Dadkhah , Volume 25, Issue 1 (3-2023)
Abstract
Background and Objective: Echocardiographic measurement of ventricular elastance is essential for evaluating cardiac function. With the technological advancements in echocardiography devices, assessing fetal heart function has become more accurate. Ventricular elastance reflects ventricular function, while arterial elastance measures ventricular afterload. Ventricular-arterial coupling demonstrates the interaction between the ventricle and artery. This study aimed to estimate ventricular end-systolic elastance, arterial elastance, and ventricular-arterial coupling using a non-invasive echocardiographic method.
Methods: This descriptive-analytical study was conducted on 67 fetuses with a gestational age of 19-24 weeks (38 female fetuses and 29 male fetuses) and 43 infants aged 10-60 days (25 female and 18 male) referred to the cardiac echocardiography clinic of the Children's Medical Center over a period of 14 months. Mothers and infants were healthy, and there was no structural heart disease in the fetuses and infants. Those with abnormal rhythm, a vague view, and an unfavorable quality of Doppler signal were excluded. Ventricular end-systolic elastance (Ea), arterial elastance (Ees), and ventricular-arterial coupling (Ea/Ees) were compared in fetuses with the calculated values in newborns. An estimation of the normal value for ventricular and arterial elastances and ventricular-arterial coupling in healthy fetuses and newborns were obtained.
Results: The mean arterial elastance of fetuses and newborns was determined as 84.4±20.04 mmHg/ml and 12.6±2.88 mmHg/ml, respectively (P<0.05). The mean ventricular elastance of fetuses and newborns was 88.5±20.49 mmHg/ml and 15.07±2.89 mmHg/ml, respectively (P<0.05). Fetal and newborn ventricular-arterial coupling were calculated as 0.96±0.14 mmHg/ml and 0.84±0.13 mmHg/ml, respectively (P<0.05).
Conclusion: The amounts of arterial and ventricular elastance and ventricular-arterial coupling in fetuses were significantly higher than infants and decreased with increasing age.
Sajjad Pourbagher, Abdolreza Bay, Alireza Heidari, Volume 25, Issue 2 (7-2023)
Abstract
Background and Objective: Non-Governmental Organizations (NGOs) have been active in the field of health for a long time and have played a key role in it, but these organizations are less known to the public for the promotion of social health and are not much considered by the planners and managers of the health system. This study was conducted to determine the challenges of NGOs’ to promote social health in Iran.
Methods: In this qualitative study, 15 Iranian managers and scientific and executive experts of the Ministry of Health, Ministry of Interior, Governorate, and Universities of Medical Sciences of the country were selected by purposeful sampling during 2021. Data were collected using an interview guide and semi-structured in-depth interview methods. After recording and transcribing, the data were analyzed by content analysis.
Results: The challenges of NGOs to promote social health in Iran were classified into six main themes of planning, organizing, functional, political, economic, and sociocultural challenges, and 33 sub-themes. Most of the participants emphasized the weak role of non-governmental organizations in improving social health and considered it a result of the mentioned challenges.
Conclusion: Empowering non-governmental organizations by formulating a strategic and operational plan and attracting financial resources from various government, private, and charitable sectors will greatly help to strengthen them to advance social health promotion programs.
Hengameh Ahmadi , Arman Eslami , Mohammad Reza Honarvar , Amrollah Sharifi , Volume 25, Issue 2 (7-2023)
Abstract
Background and Objective: Nutritional knowledge can affect food choices and, as a result, sports performance. The study of nutritional knowledge, attitude, and performance in athletes can play a fundamental role in choosing the type of training and adapting suitable dietary interventions. This study was done to evaluate the knowledge, attitude, and nutritional performance of male bodybuilding athletes in Gorgan, Iran.
Methods: This descriptive-analytical study was done on 104 male bodybuilding athletes over 18 years old with a history of at least three months of continuous bodybuilding who were randomly selected from 13 bodybuilding clubs in Gorgan, Iran during 2020. Parmenter and Wardle’s standard questionnaire measured athletes’ nutritional knowledge, attitude, and performance. The questionnaire was completed by the athletes with the guidance of the researcher. A trained nutritionist collected anthropometric and body composition data using an Omron BF511 device.
Results: Poor nutritional knowledge, poor dietary attitude and poor nutritional performance was observed in 67.3%, 33.65% and 77.88% of the athletes respectively. A significant correlation was observed between nutritional knowledge with weight (r=0.23, P=0.02), BMI (r=0.27, P=0.01), and body fat percentage (r=0.22, P=0.02). Also A significant correlation was determined between nutritional performance with body weight (r=0.31, P<0.001), BMI (r=0.27, P<0.001), exercise time per week (r=0.22, P=0.02), and exercise timespan (r=0.32, P<0.001).
Conclusion: The level of knowledge, attitude, and nutritional performance of bodybuilding athletes was weak.
Negar Asgari , Mohamad Hasan Naeimi , Alireza Tahamtan , Samin Zamani , Volume 25, Issue 2 (7-2023)
Abstract
Background and Objective: Multiple sclerosis (MS) is an autoimmune disease that targets the central nervous system. Various studies have shown that several factors influence this disease’s occurrence and prevent its progress. Multiple studies have shown that several factors affect this disease’s occurrence and prevent its progress. Helicobacter pylori can be mentioned among these factors. This study was conducted to determine Helicobacter pylori infection in MS patients and healthy individuals.
Methods: This case-control study was conducted on 100 patients with MS (mean age: 36.99±9.87 years) and 100 healthy subjects (mean age: 38.05±11.38 years) in Golestan province, north of Iran during 2021. The case group included eighty relapsing-remitting cases and twenty secondary progressive cases. Blood samples were taken from both groups, and after separating the serum using the ELISA test, anti-Helicobacter pylori antibody (IgG) was detected by determining the antibody titer.
Results: Helicobacter pylori IgG in the MS and control groups was 21% and 44%, respectively (P<0.05). The mean concentration of IgG in the case group was significantly lower than the control group (13.48±10.83 versus 19.78±16.14 AU/ml). The percentage of positive cases of IgG antibody against Helicobacter pylori in the relapsing-remitting and secondary progressive group of patients with MS was determined as 21.2% and 20%, respectively, and the difference between these two groups was not statistically significant.
Conclusion: The history of Helicobacter pylori infection is less than two times in patients with MS compared to healthy people probably indicate the protective role of this bacterium against this disease.
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