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Background and Objective: Today, drug abuse is one of the most important medical and social problems of world population, which can be a threat to human’s health. Cannabis as a common substance can create psychotic symptom, psychiatric disorders and antisocial behaviors. This study was designed to compare the prevalency of psychoticism and neuroticism among cannabis and non-cannabis abusers in this region of the country. Materials and Methods: This case control study was done on100 cannabis users whom seek for drugs in public gardens of Golestan province as case group and 100 non-abusers who spend their leisure time in this place as control group. Two groups matched with regard to age and education level. The data gathered by using self-reported adult version of Eysenck Personality Questionnaire (EPQ). The data was analyzed in the SPSS-13.5 software by Chi-square, t-test and Mann-Whitney. Results: The mean score of psychoticism and neuroticism in case and control group was 9.37 and 5.72 respectivley (P<0.05). The mean score of neuroticism in cases and controls was 15.9 and 12.19, respectivley (P<0.05). The relationship between psychoticism and patterns of cannabis consumption was significant (P<0.05). There was a relationship between cannabis consumption and the history of drug misabuse in other substances in cannabis users and in their families. Conclusion: The result of this study can clarify the importance of preventing intervention in substance abuse for improving mental health.

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The Iranian elderly population is rapidly growing. Currently more than 5 million Iranians are over 60 years of age which corresponds to nearly 7.26 percent of the population of the country. It is estimated that more than 10 percent of the population of the country will be elderly in the forthcoming twenty years. Structural and physiological changes which occur in the elderly cardiovascular system include: stiffness of the vasculature, decreased relaxation capacity of the heart during diastole, decreased efficiency of cardiac contraction during exercise, weakened heart muscle response to stimulation by adrenaline, and orthostatic hypotension. In the elderly people we are confronting with increased frequency of cardiovascular diseases especially myocardial infarction, stroke, isolated systolic hypertension, calcific aortic stenosis, orthostatic hypotension, and syncopal attacks due to sick sinus syndrome, complete heart block, atrial fibrillation or other rhythm disorders. Alteration in cardiovascular status in the elderly has undesirable effects on their quality of life and longevity. Myocardial infarction is the most common cause of death in the elderly however cardiac arrhythmias and valvular heart disease are other important cardiovascular disease in the old people. Diagnosis of these disorders in the elderly requires special consideration since coexistence of structural/functional changes in the old age with cardiovascular disease would alter the classic features of these disorders and result in delay in their appropriate management. Biological aging as evaluated by reduced telomere length has a strong impact on the incidence of cardiovascular disorders especially coronary heart disease and chronic heart failure. This phenomenon could possibly explain interindividual susceptibility to cardiovascular disorders.