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Background and Objective: Post-operative nausea vomiting (PONV) and laryngospasm are the most common of complication following surgery. This study was conducted to compare the incidence of laryngospasm and PONV after pediatric infra umbilical surgery using two anesthetic methods: control ventilation and spontaneous respiration. Materials and Methods: This double-blind clinical trial study was conducted on 192 children with 2-7 year-old undergoing infra-umbilical surgery of ASA-I class with the estimated operation period of an hour in Tehran pediatric hospital, Tehran-Iran during 2009-10. The patients were randomly divided into two groups: controlled ventilation and spontaneous respiration. After anesthetization, Atracurium was injected to the control ventilation (CV) group and anesthesia continued with mechanical ventilation. For the patients of the second group (spontaneous respiration/SR), after the gradual increase of the dose of halothane and certainty of the optimal depth of anesthesia, patients were intubated to allow spontaneous respiration. After intubation, all patients were anesthetized with Halothane 1-2% and the N2O/O2. The rate of nausea, vomiting, laryngospasm, excessive post-operative discharge was recorded. Data were analyzed using SPSS-13, student’s t-test, chi-square and Fisher’s exact tests. Results: Post-operative nausea was non significantly higher in CV group (8%) than SR (6.52%). The rate of vomiting was higher in CV (16%) as compared to SR group (2.17%). (P<0.001, RR=8.57, CI: 1.91-38.41). The rate of laryngospasm at the end of the surgery was higher in CV group (15.21%) as compared to SR group (26%) (P<0.02, RR= 0.94, CI: 0.05-1.77). The rate of excessive discharge at the end of the surgery was significantly higher in CV group (52%) in comparison with SR group (11.95%) (P<0.001, RR=0.94, CI: 0.05-1.77). Conclusion: This study showed that in infra-umbilical surgeries in a period of less than an hour the incidence of post-operative vomiting and laryngospasm is higher in control ventilation group than spontaneous respiration group, which might be due to the injection of neostigmine to counter-act the effects of muscle relaxants.

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Background and Objective: Opium use is one of the most common problems that impose significant social, psychological, and economic burdens on societies. Understanding the factors involved in the treatment of opium use is essential. This study aimed to evaluate inhibitory response and impulsivity in opium users.
Methods: This descriptive-analytical study was conducted on 170 opium users (139 men and 31 women) who visited the Methadone Maintenance Treatment Center in Gorgan, Iran during 2022, selected through convenience sampling. The Stop Signal Task (SST) was used to assess participants' inhibitory response, and the Barratt Impulsiveness Scale (BIS) was used to measure impulsivity levels.
Results: The average overall impulsivity score was 67.8±11.85. The average correct responses were 45.09±5.67, incorrect responses were 4.51±3.95, and delays were 0.96±2.32. The mean response time to each stimulus was 1290±512.83 milliseconds. There was a statistically significant correlation between impulsivity dimensions and age, correct responses and education level, and response time for inhibitory control with age and education level (P<0.05). There was no statistically significant correlation between the various dimensions of inhibitory response and impulsivity (cognitive impulsivity, non-planning impulsivity, and motor impulsivity) and overall impulsivity.
Conclusion: Opium users are generally impulsive. Additionally, younger individuals and those with lower education levels are more impulsive compared to others.