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In this case-control study, 58 transfusion-dependent Thalassemic patients compared with 46 normal healthy persons on study of their thyroid size & function. In this study, thalassemia patients divided in two groups: Group one 31 patients with (Ferritin<1500) and group two 27 patients with (Ferritin>1500) and 3rd one was named control group (46 healthy persons). These groups were compared to achieve the best possible results and conclusion out of 31 patients. From first group 26 people had normal thyroid function test only 5 patients (16%) had goiter. From 27 patients in second group, 5 people (19%) had normal thyroid and 22 patients had goiter, in 3rd group 29% had normal thyroid, the difference between second and third groups were significant (P<0.01). In second group T4 level were lower than control, instead the TSH level were more than control group. The difference in second and third group were significant. The mean of T3 and T4 in group one and three don’t have significant differences. Conclusion: The goiter incidence and hypothyroidism in major Thalassemia with poor control (Ferritin>1500) are high.

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The term Noonan syndrome has been applied to phenotypic male and female who have certain anomalies that occur also in female with Turner’s syndrome. These patients have normal karyotype. The disorder is very rare. The most common abnormality are short stature, webbing of the neck, Pectus Carinatum or Pectus excavatum, congenital heart disease. This particular case is a 8-year-old girl-patient who referred to pediatric clinic with short stature. Another abnormality in these patients is abnormal facies (Hypertelorism, hypogonadism, piqure chest and webbing of the neck). The patient had moderate mental retardation. Chromosomal analysis revealed 46xx cytogenetic distinguished Noonan syndrome.

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Background and Objective: Childhood obesity is a significant public health concern due to its impacts on childhood physical and psychological health with subsequent adulthood complication. The aim of this study was to determine some related factors of obesity and overweight in girls' secondary school. Materials and Methods: This cross-sectional study was performed in Gorgan Northern Iran, during 2005-06. The subjects selected by stratified random sampling. Age, height, weight, BMI, daily time of television watching, frequency of physical activity and snack consumption was recorded by parents in a questionnaire sheet during a week. Data were analyzed by using SPSS-11.5 software, chi-square and ANOVA tests. Results: In this study, 6.3% and 41.7% of subjects were obese and overweight, respectively. The mean of BMI of girls was 19.69±4.6 kg/m2. The prevalence of obesity and overweight in Fars ethnic group was more than others (P<0.05). Average spending time for television watching was 2.35±0.98 hours and the same index was higher among the obese and overweight girls but, this difference was not significant. Food consumption during watching television, frequency and duration of physical activity were significantly related with obesity and overweight (P<0.05). Conclusion: This study showed that low physical activity and imbalanced nutritional behavior are related to obesity and overweight among secondary school girls in Gorgan-Northern Iran.

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Background and Objective: The metabolic syndrome is a cluster of metabolic disorders that are associated with elevated risk of cardiovascular diseases and type-II diabetes. This study investigated the prevalence of metabolic syndrome among adolescents population in Gorgan, Northern Iran - 2009.

Materials and Methods: A cross-sectional survey was conducted involving 450 adolescents 15-17 years, selected through 2 stage cluster randomized sampling from high schools. Anthropometric measurements, blood pressure, fasting blood glucose and lipid profile were assessed. Metabolic syndrome was defined according to NHANES III criteria. Data was analyzed by SPSS-16 software, Chi-Square and logestic regration.

Results: The overall metabolic syndrome prevalence was 3.3% (CI 95%:1.8–5.4). More than half of cases (54.6%) had at least 1 or 2 components. High triglyceride level was the most common disorder in both genders (boys 27.6%, girls 52.4%) and then low HDL cholesterol level (17.3%) and central obesity (7.6%) were common among boys and girls respectively. Where as abdominal obesity in boys (0.9%) and hypertension in girls (3.1%) were less common.

Conclusion: This study showed that the rate of metabolic syndrome is slightly lower but the obsity in adolescents is higher than other parts of country.

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Background and Objective: Malnutrition is considered as one of most serious disorder in childhood. This study was carried out to determine the prevalence of malnutrition and its relation to serum level of Magnesium, Zinc, Iron and Calcium in 6-36 months hospitalized children. Methods: In this case-control study upon CDC chart, 166 children were in control group diagnosed with no malnutrition and 151 children were also in case group with malnutrition. BMI and serum level of Magnesium, Zinc, Iron and Calcium were measeared for each child. Results: Out of 151 children with malnutrition, 128 (84.76%) and 23 (15.23%) were involved in mild and moderate malnutrition, respectively. The serum level of Magnesium and Zinc in case group was non-significantly lower than controls, while the serum level of Calcium and Iron non-significantly higher than controls. BMI was significantly reduced in cases in compared to controls and this reduction was related with malnutrition (95% CI: 0.38-0.59, OR=0.47, P<0.05). Conclusion: Malnutrition in 6-36 month children was not related to serum level of Zinc, Magnesium, Iron and Calcium, while children with malnutrition had lower body mass index.