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The prevalence of Co-infection with HCV and HDV in HBV infected patients in Golestan province of Iran
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Gholamreza Roshandel   1, Shahryar Semnani , Nafiseh Abdolahi , Sima Besharat , Abbas Ali Kashtkar , Hamid Reza Joshaghani , Abdolvahab Moradi , Khodaberdi Kalavi , Saba Besharat , Ali Jabbari , Mohammad Javad Kabir , Seyed Ahmad Hosseini , Seyed Mahdi Sedaghat , Danyal Roshandel , Ahmad Danesh |
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Abstract: (22456 Views) |
| Background & Objective: Hepatitis B virus (HBV) infection is one of the most important health problems all over the world. This study was conducted to determine the co-infection of hepatitis C virus (HCV), hepatitis D virus (HDV) in HBV infected patients in Golestan province of Iran. Materials & Methods: This population based cross sectional study was done in 2004. 139 HBsAg positive cases were assessed for co-infection with HCV and HDV. Serologic tests were done by ELISA method using available kits. Data were analyzed by SPSS-12 and STATA8 software. P-values of less than 0.05 were considered as significant. Results: Sixty eight (48.9%) of 139 cases were males and 71 (51.1%) were females. The mean (±SD) of participant's age was 41.89 (±11.3) years (range: 25-64 years). Anti-HCV and Anti-HDV antibodies were positive in 17 (12.3%) and 8 (5.8%) cases, respectively. Females were more infected with HCV and HDV than males. But the differences were not significant. Conclusion: The prevalence of co-infection with HCV and HDV in HBV infected cases is relatively high and notable in Golestan province of Iran. Because of negative effects of these co-infections in clinical outcome of the disease, it is recommended to assess possible HCV and HDV infection in individuals with HBV infection. This may result in more efficient management of the disease. |
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| Keywords: HBV, HCV, HDV, Golestan |
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Full-Text [PDF 235 kb]
[English Abstract]
(15026 Downloads)
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Type of Study: Short Communication |
Subject:
General
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