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Relationship between utrine cervical carcinoma and oral contraceptives
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Vaisy A *1   , Lotfinejad Sh2 , Zhian F3 |
1- MSc in Midwifery, Islamic Azad University Mahabad Branch, Mahabad, Iran , a.veisy@yahoo.com
2- Associate Professor, Department of Pathology, Faculty of Medicin, Urmia University of Medical Sciences, Urmia, Iran
3- Pathologist, Mahabad, Iran |
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Abstract: (16252 Views) |
| Background and Objective: The utrine cervical cancer is the third common cancer among women word-wide. Oral contraceptives (OCs) have characterized as one of the possible risk factors for cervical cancer which are daily used by millions of women. The objective of this study was to determine the relationship between utrine cervical carcinoma and oral contraceptives. Materials and Methods: This case - control study was done on 128 patients with utrine cervical cancer as cases and 128 healthy women as controls in Tehran, Iran during 2008. The cases matched with controls according to age, history of abortion, number of deliveries, and social-economical status. Data were analyzed using SPSS-11, student’s t-test, Chi-Square, Pearson's correlation and Fisher’s exat tests. Results: Significant correlation was observed between utrine cervical cancer and the history of using and duration of oral contraceptives (P<0.05). Eighty-one (66.3%) and 46 (35.9%) of subjects in case and control groups used oral contraceptives, respectively. The possibility of utrine cervical cancer through oral contraceptives consumption was 3.072 (CI 95% 1.05-2.91) and this rate increased to 5.2 times after consuming the oral contraceptives for longer than 8 years. Conclusion: This study showed that the usage of oral contraceptives increase the possibility of utrine cervical cancer by 3 times. |
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| Keywords: Cancer, Utrine cervical, Oral contraceptives |
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Full-Text [PDF 253 kb]
[English Abstract]
(22281 Downloads)
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Type of Study: Case - Control Study |
Subject:
Obstetrics and Gynecology
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