Volume 6, Issue 1 (3-2018)
Abstract
(6852 Views) |
Full-Text (PDF)
(2253 Downloads)
|
Graphical Abstract
|
Highlights
- It has been suggested that various epigenetic deviations play a major role in the pathogenesis of endometriosis.
- Steroidogenic factor 1 (SF-1; NR5A1) is an essential transcription factor for estrogen biosynthesis in endometrial cells.
- Here, we aimed to compare the methylation status of the SF-1 gene promoter region in women with endometriosis in comparison to healthy subjects.
- The methylation status of SF-1 gene promoter was decreased significantly in endometriosis samples.
- SF-1 gene promoter hypomethylation could increase the relative expression of SF-1 gene in endometriosis which may lead to the development or progression of the disease.
Abstract
(6582 Views) |
Full-Text (PDF)
(2385 Downloads)
Abstract
(11942 Views) |
Full-Text (PDF)
(2322 Downloads)
Abstract
(13359 Views) |
Full-Text (PDF)
(2382 Downloads)
Abstract
(6671 Views) |
Full-Text (PDF)
(2548 Downloads)
Abstract
(12617 Views) |
Full-Text (PDF)
(2512 Downloads)
Abstract
(11233 Views) |
Full-Text (PDF)
(2194 Downloads)
Export as:
HTML
|
XML
|
RSS