Volume 9, Issue 1 (3-2021)                   Jorjani Biomed J 2021, 9(1): 24-31 | Back to browse issues page

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nameni F, shahdusti S, hashemi M. Effect of Weight Training and Whey Protein on Atrial Natriuretic Peptide, Brain Natriuretic Peptide and Galactin-3. Jorjani Biomed J. 2021; 9 (1) :24-31
URL: http://goums.ac.ir/jorjanijournal/article-1-785-en.html
1- Department of Sport Physiology, Varamin Pishva Branch, Islamic Azad University, Varamin, Iran , nameni@iauvaramin.ac.ir
2- Department of Sport Physiology, Varamin Pishva Branch, Islamic Azad University, Varamin, Iran
Abstract:   (450 Views)
Background and Objective: Clinical studies have indicated, that exercise activity and supplementation may have different effects on heart function and health. The aim of this study was to assess the effects of weight training with whey protein supplementation on ANP, BNP, and Galactin-3 in 60-65 years old sedentary men.
Material and Methods: This study was based on a quasi-experimental design. The sample population was selected from volunteers out of the Kahrizak charity sanitarium of the Tehran province. Forthy men were randomly assigned to 4 groups (control, exercise, whey protein, and exercise + whey protein). Whey protein and exercise + whey protein groups were asked to consume whey protein. Training protocol lasted for 6 weeks. Blood levels of ANP, BNP, and Galactin-3, before and after the study were measured. Normality and variance heterogeneity was assessed using Shapiro-Wilk and Levene's tests respectively. The significance of differences between training and supplementation groups was assessed by ANOVA and LSD hock post-test.
Results: The results showed that weight training program and in combination with whey protein supplementation significantly reduced Atrial natriuretic peptide (P=0.001), Brain natriuretic peptide (P=0.001), and Galactin-3 (P=0.001), compared to the control group (P<0.01).
Conclusion: The reduction of cardiac injury indices and structural and physiological recovery and the increase of cardiac function have been affected by the synergy of his training and protein.
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Type of Article: Original article | Subject: General medicine
Received: 2021/01/10 | Accepted: 2021/02/28 | Published: 2021/03/30

References
1. Samavat T, Hojjatzadeh A, Shams M. Ways to prevent and control cardiovascular diseases. Ministry of health. Treatment and Medical Education. Deputy Minister of Health. Tehran; second edition; 2013:73-82.
2. Mousavi H, Rana A. Exercise and the heart and its effect on the circulatory system. 6th National Conference on Management Research and Humanities in Iran. Tehran. Mod ber Management Research Institute; 2018.
3. Nowson C, O'Connell S. Protein Requirements and Recommendations for Older People: A Review. Nutrients.2015 Aug; 7(8):6874-6899. [view at publisher] [DOI] [Google Scholar]
4. Camargoa LR, Donedab D, OliveiraVR. Whey protein ingestion in elderly diet and the association with physical, performance and clinical outcomes. Contents lists available at Science Direct. Experimental Gerontology, journal homepage: www.elsevier. com/ locate /expgero. [Google Scholar]
5. Bosnjak I, Selthofer-Relatic K, Vcev A. Prognostic value of galectin-3 in patients with heart failure. Dis Markers 2015. [view at publisher] [DOI] [Google Scholar]
6. Smith A, Morgan PJ, Plotnikoff RC, Stodden DF, Lubans DR. Mediating effects of resistance training skill competency on health-related fitness and physical activity: The ATLAS cluster randomized controlled trial. Journal of sports sciences. 2016; 34(8):772-779 . [view at publisher] [DOI] [Google Scholar]
7. Ventetuolo CE, Levy M. Cardiac Biomarkers in the Critically, Division of Pulmonary Allergy and Critical Care Medicine. CJASN 2010;3(2)571-577. [Google Scholar]
8. Pereira ES, Krause Neto W, Calefi AS, Georgetti M, Guerreiro L, et al. Significant Acute Response of Brain-Derived Neurotrophic Factor Following a Session of Extreme Conditioning Program Is Correlated With Volume of Specific Exercise Training in Trained Men. Front. Physiol. 2018; 9: 823. [view at publisher] [DOI] [Google Scholar]
9. Azevedo KPM, Oliveira VH, Medeiros GCBS, Sousa Mata AN, García DA, et al. The Effects of Exercise on BDNF Levels in Adolescents: A Systematic Review with Meta-Analysis, Int. J. Environ. Res. Public Health 2020, 17 :(17), 6056. [view at publisher] [DOI] [Google Scholar]
10. Hamasaki H. The effect of exercise on Natriuretic peptide in individual's without health failure. Sporter.SI. 2016; 4(2):32-41. [view at publisher] [DOI] [Google Scholar]
11. Ahmadizad S, Zahediasl S, Sajadi M et al. Effects of twelve weeks of resistance training on the resting levels of cardiac and related hormones in healthy men. Physiology and Pharmacology 2012; 15(4):517-526. [Google Scholar]
12. Yurtdas M, Ozcan IT, Camsar A et al. NT-Pro-BNP levels and their response to exercise in patients with slow coronary flow. Arq Bras Cardiol 2012; 99(6):1115-1122. [Google Scholar]
13. Qahramani M, Karbalaeifar S. The effect of intermittent exercise intensity on ANP and BNP gene expression in myocardial infarction from myocardial infarction. Quarterly Journal of Exercise Physiology 2017; 9(36):159-172. [Google Scholar]
14. Davies R, Bass JJ, Carson BP, Norton C, Kozior M, et al. The Effect of Whey Protein Supplementation on Myofibrillar Protein Synthesis and Performance Recovery in Resistance-Trained Men, Nutrients 2020, 12, 845. [view at publisher] [DOI] [Google Scholar]
15. Frestedt JL, Zenk JL, Kuskowski MA et al. A whey-protein supplement increases fat loss and spares lean muscle in obese subjects: a randomized human clinical study. Nutr Metab (Lond) 2008;5(1):1-7. [view at publisher] [DOI] [Google Scholar]
16. Hötting K, Schickert N, Kaiser J, Röder B, Schmidt-Kassow M. The Effects of Acute Physical Exercise on Memory, Peripheral BDNF, and Cortisol in Young Adults, Hindawi Publishing Corporation Neural Plasticity Volume 2016, Article ID 6860573, 12 pages . [view at publisher] [DOI] [Google Scholar]
17. Grandin EW, Jarolim P, Murphy SA et al. Galectin-3 and the development of heart failure after acute coronary syndrome:pilot experience from PROVE IT-TIMI 22. Clin Chem 2012; 58(1):267-273. [view at publisher] [DOI] [Google Scholar]
18. Salvagno GL, Schena F, Gelati M et al. The concentration of high-sensitivity troponin I, galectin-3 and NT-pro BNP substantially increase after a 60-km ultramarathon. Clin Chem Lab Med 2013; 52(2):1-6. [DOI] [Google Scholar]
19. Hättasch R, Spethmann S,de Boer RA et al. Galectin-3 increase in endurance athletes. Europ J prevents cardiol 2013; 21:1192-1199. [view at publisher] [DOI] [Google Scholar]
20. Samiei A, Behpoor N, Tadibi V, Fathi R. The Effect of High Intensity Aerobic Exercise on Levels of Galectin-3 and Protein Kinase C in Diabetic Male Rats, J Clin Res Paramed Sci. 2020 June; 9(1):e80362. [view at publisher] [DOI] [Google Scholar]
21. Khajeian N, Moghadasi M. Effect of 8 weeks regular endurance training on galectin-3 changes after a strenuous aerobic exercise, Journal of Physical Activity and Hormones 2017; 1(3): 029-038. [view at publisher] [Google Scholar]
22. Ghassami M, Naragh S. Galectin-3 concentrations in response to an exhaustive aerobic exercise. Journal of Physical Activity and Hormones 2018;2(4):039-050. [view at publisher] [Google Scholar]
23. Qasami M. The effect of a debilitating aerobic exercise session on NT-Pro BNP and galactin-3 changes in non-athlete men. Master. Faculty of Physical Education and Medical Sciences. IAU, Shiraz Branch; 2015.
24. Saeedi H. The effect of an exhausting endurance exercise session on plasma levels, cerebral natriuretic peptide and galactin-3 semi-professional male runners. Master. School of Physical Education and Medical Sciences. Sports Sciences. Birjand University; 2016.
25. Gerdes SK, Harper J. Bioactive components of whey and cardiovascular health. Appli Mono Cardiovascular Health 2001; 6:182-194. [Google Scholar]
26. Abdolrezaii A,Nairi H, Bagheri Moghaddam A et al. Effects of whey protein supplementation on the expression of genes involved in signaling pathways affecting hypertrophy and thermogenesis in athletes. 7th Conference on Dietary Supplements; 2018.
27. Golzar AK,Shaykh al-Islami Watani F, Kashkoli D, Moradi V, Farhangian H.The effect of Whey Isolate protein supplementation and strength training on weight loss, body composition, strength and muscle hypertrophy in overweight young men. Nutrition Sciences and Food Industry of Iran Summer 2012; 25: 37- 46.
28. Sharifi Moghadam A, Askari R, Hamedinia MR et al. The effect of resistance training programs with and without blood flow restriction on serum CAF, P3NP and muscle function in elderly women. Life Sciences and Sports 2018; 10(3):359-375. [view at publisher] [Google Scholar]
29. Chopra S, Cherian D, Verghese PP, Jacob JJ. Physiology and clinical significance of natriuretic hormones. Indian J Endocrinol Metab. 2013; 17(1):83-90. [view at publisher] [DOI] [Google Scholar]
30. Wilhelm M, Nuoffer JM, Schmid JP, Wilhelm I, Saner H. Comparison of pro-atrial natriuretic peptide and atrial remodeling in marathon versus non-marathon runners. 2012; 109 (7): 1060-5. [view at publisher] [DOI] [Google Scholar]
31. Lipari EF, Lipari D, Valentino B. Modifications of atrial natriuretic peptide and vasopressin peptides in the rat hypothalamic supra optic nucleus during resistance training. Ital J Anat Embryol. 2010; 115(3):211-7. [view at publisher] [Google Scholar]
32. Raha D, Tortorella C, Neri G, Prasad A, Raza B, Raskar R, et al. Atrial natriuretic peptide enhances cortisol secretion from guinea-pig adrenal gland: evidence for an indirect paracrine mechanism probably involving the local release of medullary catecholamines. Int J Mol Med. 2006; 17 (4): 633-658. [view at publisher] [DOI] [Google Scholar]
33. Van den Berg MP, Van Gelder IC, VanVeldhuisen DJ. Depletion of atrial natriuretic peptide during longstanding atrial fibrillation. EP Europace.2004; 6(5):433-437. [view at publisher] [DOI] [Google Scholar]
34. Bentzen H, Pedersen RS, Nyvad O, Pedersen EB. Influence of training habits on exercise-induced changes in plasma atrial and brain natriuretic peptide and urinary excretion of aquaporin-2 in healthy man. Scandinavian Journal of Clinical and Laboratory Investigation.2002; 62(7):541-551. [view at publisher] [DOI] [Google Scholar]
35. Guazzi M, Vitelli A, Arena R. The effect of exercise training on plasma NTpro- BNP levels and its correlation with improved exercise ventilator efficiency in patients with heart failure.2012; 2(158):290-9. [DOI] [Google Scholar]
36. Ma KK. Ogawa T. De Bold AJ. Selective up regulation of cardiac brain natriuretic peptide at the transcriptional and translational levels by pro inflammatory cytokines and by conditioned medium derived from mixed lymphocyte reactions via p38 MAP kinase. J Mol Cell Cardiol. 2004; (36):505-13. [view at publisher] [DOI] [Google Scholar]
37. Sarullo MF, Gristina T, Brusca I, Milia S, Raimondi R, Sajeva M, et al. Effect of physical training on exercise capacity gas exchange and N-terminal pro-brain natriuretic peptide levels in patients with chronic heart failure. Eur J Cardiovasc Prev Rehabil. 2006; (13):812-7. [view at publisher] [DOI] [Google Scholar]
38. Potter LR. Natriuretic peptide metabolism, clearance and degradation. FEBS J.2011; 278(11): 1808-1817. [view at publisher] [DOI] [Google Scholar]
39. Nathalie M. Benda TM. Eijsvogels AP. Dijk M, Hopman TE. Changes in BNP and cardiac troponinI after high-intensity interval and endurance exercise in heart failure patients and healthy controls. Int J Cardiol. 2015; 1(184):426-7. [view at publisher] [DOI] [Google Scholar]
40. Bordbar S, Moghaddasi M. Comparison of acute and long-term effects of resistance and endurance training on the level of natriuretic peptide in middle-aged men. Sports and motor life sciences.2013; 5(9):42-48. [Google Scholar]
41. De Boer RA, Yu L, Van Veldhuisen DJ. Galectin-3 in Cardiac Remodeling and Heart Failure. Curr Heart Fail Rep. 2010; 7:1-8. [DOI] [Google Scholar]
42. Kim H, Lee J, Hyun JW, et al. Expression and immune histochemical localization of galectin-3 in various mouse tissues. Cell Biol Int. 2007; 31:655-662. [view at publisher] [DOI] [Google Scholar]
43. Haug A, Høstmark A, Harstad O. Bovine milk in human nutrition - a revisew. Lipids in Health and Discase. 2007; 6( 25):1-16. [DOI] [Google Scholar]

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