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S Shojaee, F Hosseine, N Fakhr-E-Rad, B Bijaree, M Sekhavati, M Fereidouni,
Volume 7, Issue 2 (summer[PERSIAN] 2013)
Abstract

Abstract Background and Objective: Having knowledge about potential risks and the usage of safety equipment in laboratories can decrease the risk of occupational exposure. The aim of this study was to evaluate the predisposing factors for occupational exposure and to assess the usage of safety equipment among personnel of medical diagnostic laboratories in Birjand. Material and Methods: In this descriptive analytic study, all staff of laboratories was assessed by using a questionnaire including demographic data, type of accidental exposures and the use of protective equipment. Using SPSS software, we analyzed the data. Results: Of 110, 84 (76%) have at least one accidental exposure to patients’ specimens in that 55% of accidents are related to sample preparation step. In 82% of contacts, carelessness is the underlying cause of exposure. Gown, glove, fume hood and mouth mask are routinely used by 97%, 48%, 34%, 1% of personnel, respectively. Nearly all of (97%) personnel were vaccinated against hepatitis B and 78% of them have performed routine blood test for detecting any infections. Conclusion: The results of current study show that accidental exposures to patients’ samples are common among personnel of medical diagnostic laboratories. The level of preventive education and the rate of safety equipment usage are low therefore, we recommend planning of some training sessions to persuade the personnel for using safety equipment. Keywords: Medical laboratory, Occupational Exposure, Specimens, Vaccination
Mohammad Sadegh Naghizadeh, Mohsen Naseri, Gholamreza Anani Sarab, Afshin Derakhshani, Mohammad Fereidouni,
Volume 17, Issue 6 (Nov-Dec 2023)
Abstract

Background: Atopic dermatitis (AD) is a common allergic disorder. Detection of responsible pathogenic allergens in AD patients by reliable methods has a fundamental role in the prevention, management, and treatment of AD. This study was conducted to determine the most common allergens by the skin prick test (SPT) and immunoblotting among AD patients referring to an allergy clinic in Birjand City, Iran.
Methods: The presence of AD was confirmed by an expert allergist. Serum levels of total and specific immunoglobulin E (sIgE) against 30 food and inhalant allergens were evaluated by a commercial immunoblotting kit (AlleisaScreen).
Results: The skin prick test was performed by a battery of 17 allergens. In total, 34 AD patients (mean age, 28.76 ± 17.36 years; range, 1-60 years; F/M ratio: 0.88) were enrolled in this study. The sensitization rates to at least 1 fungus, pollen, food, or indoor allergen by the immunoblotting method were 32.35%, 61.76%, 52.94%, and 47.05%, respectively. The most prevalent allergens were ragweed (52.94), Olive tree (41.16), Eucalyptus (35.29), date palm (35.29), and grass mix (32.28).
Conclusion: The study found that 85.29% of the studied population were sensitized to at least 1 allergen. Pollens and date palms were the most common allergens among AD patients, but the pattern of sensitization in SPT and immunoblotting was not exactly similar. Detection of allergens to which patients are sensitized and avoidance can help in the management of the disease and its symptoms.

 

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