Showing 5 results for Azizi
T Ghelich, M Hashemi Karouei, I Gholampor Azizi,
Volume 8, Issue 2 (summer 2014[PERSIAN] 2014)
Abstract
Abstract Background and Objective: Because of increased resistance to antibiotics, side effects of chemical drugs and importance of medicinal plants, we aimed to assess the antibacterial effects of methanolic extract of the Polygonumbistorta plant on the E. coli (ATCC 15224), Ps. aeruginosa (ATCC 25619), B. subtilis (ATCC 6633) and Stap. Aureus (ATCC 25923). Material and Methods: After preparing the extract, its antibacterial effect was assessed via gel diffusion method, using disk / well diffusion methods to determine MIC and MBC Results: MIC of methanolic extract was 78 µg/ml for E. coli, 63×103 µg/ml for Pseudomonas aeruginosa, 39 µg/ml for Bacillus subtilis and 31×102 µg/ml for Staphylococcus aureus Conclusion: In spite of resistance of gram-negative bacteria to chemical agents, polygonum bistorta methanolic extract could inhibit the growth of E.coli and P. aeruginosa. Key words: Antibacterial, Bistorta, Escherichia Coli, Pseudomonas Aeruginosa
Seyyede Zolaikha Hashemi Chashmi, Valiollah Dabidi Roshan, Sohail Azizi,
Volume 10, Issue 5 (Sep-Oct-2016 2016)
Abstract
ABSTRACT
Background and Objective: Doxorubicin (DOX) is an effective anticancer drug. It has been shown that a short-term exercise performed prior to DOX-treatment has no effect on cardiotoxicity in young rats. In the present study, old and young rats were evaluated to determine the protective effects of pre-treatment with short-term exercise on DOX-induced oxidative damage in cardiac tissue.
Methods: Forty-eight male Wistar rats were randomly divided into two groups of young and old, and later divided into three sub-groups of young+DOX, young+training+DOX, young+training+salin, old+DOX, old+training+DOX and old+training+salin. The training protocol included treadmill running for 25-39 min/day at 15-17 m/min, 5 days/week for three weeks. All treatments were carried out 24h after the last exercise bout. The rats were sacrificed 48h
after DOX administration.
Results: Although DOX injection significantly affected the cardiac tissue of old rats compared to young rats, pretreatment with endurance training in DOX-treated rats caused an increase in Heat shock protein (3.02% vs. 23.36) and superoxide dismutase (30.12% vs. 31.12), and a decrease in malondialdehyde (10.92% vs. 19.60) in both old and young rats.
Conclusion: Although DOX-induced production of free radicals and cardiotoxicity in aged rats is more than that in young rats, the short-term aerobic exercise reduced the damaging effects of free radicals in the old rats more than in young ones. The concentration of antioxidant enzymes also increases with exercise in the old rats compared to young rats.
Keywords: Cardiotoxicity, Doxorubicin, Oxidative Stress, Aerobic Exercise.
Amin Farzaneh Hesari , Akram Ebrahimi, Masoumeh Azizi Zanjani , Solmaz Mahdavi,
Volume 12, Issue 1 (Jan-Feb 2018)
Abstract
ABSTRACT
Background and Objectives: Elevated blood lipid levels are correlated with risk of cardiovascular disease, especially in overweight individuals. The beneficial effect of strength training on lipid profile has been well documented. However, the effect of strength training with flow blood restriction has not been established. The purpose of this study was to compare the effect of eight weeks of strength training with and without blood flow restriction on some of the cardiovascular risk factors in overweight females.
Methods: In this study, 28 overweight females aged 18 to 24 years were randomly assigned into three groups of blood flow restriction strength training (BFRT), traditional strength training (TRT) and control. Participants in the BFRT group performed eight weeks of strength training three sessions per week at 30% of 1-repetetion maximum, while participants in the TRT group performed the training at 65-80% of 1-repetetion maximum. Cardiovascular variables, systolic blood pressure and diastolic blood pressure were measured before and after the exercise training. Data was analyzed using descriptive statistics, paired t-test and one-way analysis of variance.
Results: Triglyceride level decreased significantly in the BFRT (p=0.022) and TRT (p=0.038) groups compared with the control group. Moreover, there were no significant differences in the body mass, waist-to-hip ratio, body mass index, high-density lipoprotein, low-density lipoprotein, and cholesterol levels between the study groups (P≥0.05).
Conclusion: Our findings suggest that the BFRT and TRT may not be suitable for preventing or even reversing the physiological changes induced by obesity.
Keywords: Resistance Training, Lipids, lipoprotein, overweight.
Maryam Lotfi, Mohammad Azizi, Worya Tahmasebi, Parviz Bashiri,
Volume 14, Issue 2 (Mar-Apr 2020)
Abstract
ABSTRACT
Background and Objective: It is desirable for athletes, especially female soccer players, to consume beetroot beverage during training as a way of improving both health and performance ,. Therefore, the objective of this study was to assess the effect of beetroot juice intake on lipid profile in female soccer players.
Methods: Young and well-trained female soccer players (N=20) were included in a randomized placebo-controlled crossover study. They were categorized into two groups: experimental (beetroot beverage, n=10, age: 23.20±0.91 years, BMI: 22.57±1.54(kg/m2)) and control (placebo, n=10, age: 23±0.81 years, BMI: 23.13±0.58(kg/m2)). Subjects drank either 200 ml concentrated beetroot beverage or an equal amount of placebo 2 hours prior to their trainings for six weeks (18 session). Blood samples were taken 24 hours before and after trials. All data were compared in pretest and posttest via paired sample t-test and independent sample t-test. All statistical analyses were performed at (P≤0.05) by SPSS (version22).
Results: Beetroot juice intake increased plasma high density lipoprotein (t= -60.88, P<0.05). Triglyceride, total cholesterol, and low density lipoprotein were reduced (P<0.05). Compared with placebo, beetroot juice reduced the concentrations of triglyceride, total cholesterol, and low density lipoprotein (P<0.05).
Conclusion: Regular beetroot juice intake has significant effects on lipid profile in female soccer players, hence its suggestion for preventing diseases such as hypercholesterolemia and hypertension in female soccer players.
Key words: Soccer, Training, Dietary Supplements, Lipids.
Ali Ehsan Shahbazi, Nastaran Barati, Eissa Soleymani, Pegah Khandan Del, Abolfazl Khandan Del, Nemat Azizi , Behjat Ranjouri , Mehran Bakhtiari , Seyedmousa Motavallihaghi ,
Volume 17, Issue 6 (Nov-Dec 2023)
Abstract
Background: COVID-19 is a respiratory disease pandemic and a major global health problem that can cause acute respiratory distress syndrome (ARDS). Previous studies have shown an inverse link between toxoplasmosis and COVID-19. This study aimed to evaluate the association between COVID-19 and toxoplasmosis infection.
Methods: In this cross-sectional descriptive study, samples were taken from 360 patients, 50% of whom were men and 50% were women. Of the patients, 180 were determined to be COVID-19-positive by the ELISA kit, and 180 were in the control group. Some demographic characteristics, such as sex, age range, and occupation, were also recorded.
Results: This study was conducted on 180 COVID-19-positive patients, of whom 26.7% were in the 16-30-year age group, 25.1% were self-employed, and 31.7% had anti-Toxoplasma gondii antibodies. Among the 180 control patients, 21.1% had antibodies for T. gondii. Of the 57 patients who were co-infected with both COVID-19 and toxoplasmosis, men had higher infection rates (63.2%) than women (36.8%). There was a significant relationship between co-infections with COVID-19 and toxoplasmosis with occupation, but not with age.
Conclusion: The study found that people with toxoplasmosis infection have a 1.73 times higher risk of contracting COVID-19. The findings suggest that infectious agents could be a predisposing factor, possibly due to changes in cytokine levels.
