Volume 8, Issue 4 (supplement Issue[PERSIAN] 2015)                   mljgoums 2015, 8(4): 1-6 | Back to browse issues page

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Saadat, S, Solhjoo, K, Norouz-Nejad, MJ, Kazemi, A, Erfanian, S, Ashrafian, F. Vancomycin Resistance Pattern of Staphylococcus Aureus among Clinical Samples. mljgoums 2015; 8 (4) :1-6
URL: http://mlj.goums.ac.ir/article-1-529-en.html
Vancomycin Resistance Pattern of Staphylococcus Aureus among Clinical Samples
Saadat, S1 , Solhjoo, K 2, Norouz-Nejad, MJ3 , Kazemi, A4 , Erfanian, S4 , Ashrafian, F5
1- Young Researchers and Elite club, Islamic Azad University, Jahrom Branch, Jahrom
2- Jahrom University of Medical Sciences, Jahrom , solhjouk@yahoo.com
3- Jahrom Branch, Jahrom, Iran
4- Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom
5- Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:   (16313 Views)
Abstract Background and Objective: Vancomycin is used for treatment of methicillin-resistant S. Aureus (MRSA) infections therefore, resistance to this antibiotic is increasing. We aimed to determine the antibiotic resistance pattern and frequency of vancomycin resistant S. Areas (VRSA) strains isolated from clinical samples. Material and Methods: In this cross-sectional study, 100 S. Aureus isolates collected from hospitals in Shiraz during six months, 2012, were identified by biochemical, microbiological and molecular methods. After determination of antibiotic susceptibility pattern by disc diffusion method and vancomycin agar screening test, Minimum Inhibitory Concentration (MIC) was determined by E-test for vancomycin, thicoplanin, linezolid and quinupristin-dalfopristin. Results: The most resistant and the most sensitive antibiotic were ampicillin (%95) and quinupristin-dalfopristin (99%), respectively, and 44% of isolates were resistant to methicillin. In agar screening test, 48% of strains had reduced sensitivity and in disc diffusion 3% strains were resistant to vancomycin. In E-test method, only one isolate was resistant to vancomycin. Conclusion: given the presence of VRSA and new antibiotic resistant strains, we recommend doing some intervention to prevent from spreading these strains in hospitals. . Keywords: Clinical Specimens, Staphylococcus Aureus, Vancomycin, Antibiotic Resistance
Keywords: Clinical Specimens, Staphylococcus Aureus, Vancomycin, Antibiotic Resistance
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Research Article: Original Paper |
Received: 2014/08/31 | Accepted: 2014/08/31 | Published: 2014/08/31 | ePublished: 2014/08/31
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.