Volume 9, Issue 1 (March, April[PERSIAN] 2015)                   mljgoums 2015, 9(1): 90-96 | Back to browse issues page

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Abdollahi, E. (BSc), Tavasolian, F. (BSc), Vakili, M. (PhD), Samadi, M. (PhD). Evaluation of Serum CRP and Vitamin D in Rheumatoid Arteritis Patients and Healthy People. mljgoums. 2015; 9 (1) :90-96
URL: http://goums.ac.ir/mljgoums/article-1-611-en.html
1- MS student of Immunology, Faculty of Medicine Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2- Assistant Professor of Community Medicine, Faculty of Medicine Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3- Assistant Professor of Immunology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , samadi@ssu.ac.ir
Abstract:   (3613 Views)
Abstract Background and Objective: C- reactive protein (CRP), as an acute phase reactant and a reliable marker of inflammation, increases due to inflammatory diseases such as Rheumatoid Arteritis and infectious conditions. New evidence shows that Vitamin D may have important effects on adjusting and reducing the Immune Responses. The aim of this study was to evaluate the association between serum vitamin D as an immunomodulator factor and CRP as an inflammatory factor in Arteritis Patients. . Material and Methods: The CRP and Vitamin D were evaluated in Rheumatoid Arteritis patients confirmed by Medical records (40 men and 40 women) and in 80 healthy adult people with normal CRP and Vitamin D and no history of arteritis (40 men and 40 women). Torbidometry was used to measure CRP and Eliza for Vitamin D. Results: In patient group, the mean of CRP and Vitamin D were 95.9±9.1 Mlg/lit and 9.17±2.9 Mlg/lit, resoectively. There was a significant inverse correlation between C-reactive protein and vitamin D in Rheumatoid Arteritis patients (Pvalue= 0.03 Pearson correlation: -0.62) and that was the case for healthy people (p value: 0.04 Pearson correlation: -0.73). Conclusion: Based on the findings, inverse correlation is observed between serum vitamin D and CRP level. Keywords: Vitamin D, CRP, Rheumatoid Arteritis
Type of Study: Original Paper | Subject: Special
Received: 2014/12/28 | Accepted: 2014/12/28 | Published: 2014/12/28

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