TY - JOUR JF - J-Gorgan-Univ-Med-Sci JO - J Gorgan Univ Med Sci VL - 23 IS - 4 PY - 2021 Y1 - 2021/12/01 TI - Association of Serum Magnesium Level with Glycemic Control, Serum Lipids and Renal Function in Type 2 Diabetes Mellitus and Pre-Diabetic Patients TT - ارتباط سطح سرمی منیزیوم با وضعیت کنترل گلوکز خون، لیپیدهای سرم و عملکرد کلیه در بیماران مبتلا به دیابت نوع 2 و پیش دیابت N2 - Background and Objective: Diabetes is one of the most common non-communicable diseases with debilitating complications and mortality rate those results from insulin deficiency, resistance to it or both. The role of nutrition and some micronutrients in the development and progression of diabetes has been investigated. Studies have shown that Magnesium deficiency can reduce insulin secretion and cell resistance. This study was done to determine the association of serum Magnesium level with glycemic control, serum lipids and renal function in type 2 diabetes mellitus and pre-diabetic patients. Methods: This case-control study was done on 70 patients with type 2 diabetes, pre-diabetes and 35 healthy individuals. Fasting glucose, HbA1c, lipid profile, creatinine and Magnesium were determined. Results: Serum Magnesium level in diabetic and pre-diabetic patients were significantly lower than control group (P<0.05). Serum Magnesium level had reverses correlation with HbA1c in diabetic patients. Serum Magnesium level had reverse correlation with glycemic index (FBS, 2hpp) and creatinine in control group (P<0.05) were evaluated in all groups but there was no significant correlation between Renal function test (Cr, eGFR) and serum Mg level. Conclusion: Serum Magnesium levels in diabetics and pre-diabetics were lower than healthy individuals and had reverse correlation with HbA1c in diabetic patients. SP - 26 EP - 32 AU - Sharifnezhad, Farzad AU - Eshghinia, Samira AU - Akbari, Hamideh AD - Assistant Professor, Clinical Research Development Unit (CRDU), Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran. KW - Diabetes Mellitus KW - Magnesium KW - Prediabetic State KW - Blood Glucose KW - Creatinine UR - http://goums.ac.ir/journal/article-1-3933-en.html ER -