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Showing 1 results for Sphingolipids
Maliheh Bagheri , Amin Farzaneh Hesari, Hajar Abaszadeh , Volume 24, Issue 1 (3-2022)
Abstract
Background and Objective: Sphingosine-1-phosphate (S1P) plays an important role in muscle biology and is involved in hypertrophy and activation of satellite cells. This study was done to determine the effect of eight weeks of concurrent training with different order on S1P in fast and slow muscles in wistar rats.
Methods: In this experimental study, 40 male wistar rats (weight 180-200 gr) were randomly allocated into 5 groups including control, resistance training, endurance training, resistance- endurance training, endurance- resistance training. Resistance training consisted 1-meter ladder climbing with the loading of percent of overloading test (%75 of weight body) in the first week and increased to 30 gr per week. Endurance training consisted of running on treadmill with speed of 12 m/min and 10 minutes in the first week to 30 m/min and 60 minutes in the last week. The resistance- endurance group performed resistance training 5 minutes before endurance training and the endurance- resistance group performed endurance training 5 minutes after resistance training. The protein level of S1P was measured in flexor hallucis longus (FHL) and soleus muscles.
Results: The S1P level in fast and slow twitch muscle increased significantly in endurance- resistance training, resistance- endurance training and resistance training compared to controls (P<0.05). There were no significant differences between concurrent training with differing order.
Conclusion: It seems that exercise order in concurrent training result in no different effect on S1P level in fast and slow twitch muscles in wistar rats.
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