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This case report is about a 25-year-old patient with microangiopathic in toxemic pregnancy. Clinical manifestations are such as hemorrhage in digestive system and urinary tract accompanied with anemia thrombocytopenia, liver, and kidney, disorder. The clinical diagnosis for this patient was HELLP syndrome, with all of the clinical manifestations of this syndrome the patient was admitted to the 5th Azar Hospital in Gorgan. All of the clinical manifestations and paraclinical observation returned to normal during one and three weeks respectively. The prevalency of this syndrome among the total pregnancies is about 0.2%-0.8% and the risk of recurrence of this disorder is about 3-25%.

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Gardenerlla Vaginalis is a tiny pleomorphic gram negative mostly isolated from secretions of females with bacteria vaginosis. The organism cause infections such as endometritis, salpingitis, urethritis and in pregnant women cause the delivery of low-birth weight babies with less than 2500 grams. This study was done as a descriptive study on 200 pregnant and non-pregnant women in 2 groups, referred to gynecology and obstetric ward of Babol University of Medical Sciences. We gathered information by questionnaires then clinical examination and sampling from posterior fornix was obtained. PH values of the samples were determined, wiff test, wet mount examination and gram staining were practiced and finally the isolated bacteria from media such as HBT, PSDA, etc were examined by proper microbiologic tests to confirm the diagnosis. In this study 24% of non-pregnant and 14% of pregnant women found to be infected with GV. In 30.7% of infected women the rate of colonization of GV was high. However detection of bacterial vaginosis by clinical diagnosis has shown an incidence of 41% in non-pregnant women and 27% in pregnant women. Meanwhile 60% of non-pregnant females had positive pop-smears for GV. It should also be noted that the rate of GV infections has found to be higher during the first trimester than the second or third. Samples from patients with bacterial vaginosis show an associated increase in the number of gram negative of variable gram reaction bacilli with a decrease in the number of lactobacilli. Thus, diagnosis of bacterial vaginosis is preferably recommended to be made using simple methods such as wet mount examination and gram-staining of vaginal discharges.

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Abdominal sonography is a best method to defined implantation site of placenta. Determination of placental site is very important if the aggressive method is to be used this study design to define implantation site of placenta in 1585 pregnant women whom referred 28 wk to sonographic center to Deziani Hospital in their third trimester with routine prenatal care. Collection of data perform in nine month and the data was collected by interviewing the pregnant women using a checklist and questionnaire. The results from this investigation show that 51.79% of placenta located in fondoanterior 31.23% fondoposterior, 12.11% posterior another in lateral position and 0.18% of placenta was previa.

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Toxoplasmosis is a disease caused by a ubiquitous, obligate intra cellular protozoan Toxoplasma Gondii. Based on serological evidences, Toxoplasmosis infection is a widespread disease with regard to this fact and because to the occurrence of congenital Toxoplasmosis infections due to asymptomatic infections in pregnant women, determination of the rate of Toxoplasma antibodies (IgG, IgM) before pregnancy and finding the involved factors in increasing Toxoplasmosis prevalence seems to be necessary. This study was a cross-sectional and descriptive study and sample population was the women referred to marriage consultation the prevalence of Toxoplasma antibodies (IgG, IgM) was determined by ELISA method. Blood sample were collected randomly from 300 women referred to the center for consultation in 2001 and they was transferred to the laboratory for antibodies determination. The results showed that the general prevalence to the positive cases based on high titer of IgG was 48.3% and of IgM was 11.7%. There was not any relation between positive cases and age, education, place for residence, job, keeping domestic animals (Except cat) vegetable consumption and wash-up, but there was a relation between positive cases of IgM and keeping cat at home (P?0.025). More over 51.7% of pregnant women in Gorgan were seronegative and the were prone to acute Toxoplasmosis during their pregnancy. The results of this study confirm that the determination of the diagnostic Toxoplasmosis is an necessary test during pregnancy.

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Background & Objective: Neonatal growth indices can be influenced by either wanted, or unwanted pregnancy. This research was done to compare neonatal growth indices (Height, weight, head circumflex) to in such pregnancies in Birjand (South-east of Iran). Materials & Methods: This study case-control study was done on a total of 400 women and their neonates in the Imam Reza and Mehr maternity hospital in Birjand between 2000 to 2002. The number of case (UWP) and control (WP) were 150 and 250 respectively. Data were collected through a valid and reliable questionnaire by face to face interviewing with mothers and the determination of growth indexes of the neonates. The results were analyzed employing X² and student T-test by means of SPSS software. Results: The results revealed that the mean weight of the neonates in the case group (3151±410.4 grams) was meaningfully (P?0.05) less than the mean weight (3243±484 grams) of the neonates in the control group (WP). Besides, the mean weight gaining of mothers during their pregnancy in the cases (9±3.2 kg) was meaningfully (P<0.05) less than control group (9.7±3.4 kg). Conclusion: The results of this study, shows the impact of wanted pregnancy on weight gain and health improvement of mothers and their infants. It is therefore recommend that the health centers, mass and even high schools officials provide enough training to prevent unwanted pregnancies.

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Background&Objective: Depression during pregnancy has been indicated as more frequent than depression after child delivery. But this important phenomenon has partly been ignored. This study aims to recognize the prevalence and possible influential factors on depression among pregnant women attended to Mirza Koochek Khan Hospital in Teheran. The study designed as a cross-sectional one and included sample of pregnant women during 2 months of study. Materials&Methods: Beck depression test was employed as data gathering instrument. Moreover, socio-economic and demographic characteristics of the respondents as well as their attitudes towards some reproductive health variables were questioned. The questionnaire piloted and thereafter, 180 pregnant women completed the questionnaire with their own consensus. Results: At least 23/3% of the sample suffered from depression in different degrees, though none of them received or requested treatment. The average score of Beck test among the sample was 11/43 with 5/75 standard deviation. Logistic regression analysis demonstrated that indicators related to physical and sexual violence from husbands’ side as well as their educational attainments were more influential variables on depression inducing (respectively). Conclusion: With regard to high prevalence of depression among the respondents, and as it has been indicated in relevant studies conducted in home, the integration of depression screening through appropriate instrument such as Beck test, in mother and child health services delivery seems to be necessary. Also taking into consideration the determinant role of husbands in rise and fall of pregnancy period depression, providing educational programs for husbands in terms of their active participation in alleviating pregnancy related problems and physiological - psychological changes occur during pregnancy suggested.

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Background&Objective: Acetaminophen is a drug that is used commonly in the all time of pregnancy as a antipyretic and analgestic. The aim of this study was to determine teratogenic effects of this drug when it is used continuously before and during pregnancy. Materials&Methods: 210 virgin female Balb/c mice in a standard animal house condition were assigned in to three experimental groups and three period of time (30 mice in the each of I and II experimantal groups and 60 in III experimental group): The first experimental group subdivided in to three I10, I20, I30 subgroups that received acetaminophen once daily at dose 40mg/kg/day by gavage in 10, 20 and 30 days prior to gestation and early 10 days of pregnancy, respectively. The second experimental group divided like the previous group (II10, II20, II30) but received 40 mg/kg/day of this drug twice daily (80 mg/kg/day). The third experimental group (III10, III20, III30) received 80 mg/kg/day of acetaminophen with and without 0.14 mg/kg/day of folic acid. Mice in Control groups, received normal saline and base of drug respectively. After using standard coupling method (three female mice with one male and determination of Gestational day 0) in GD18 the dams were sacrificed and the fetuses were removed. Macroscopic observation was done by stereomicroscope. ANOVA and TUKEY tests were used by the help of 10 version of SPSS software. Results: Long consumption of acetaminophen in doses of 40 and 80 mg/kg/day in the 20 and 30 days before pregnancy and 10 days after pregnancy can induce shortened and asymmetrical limbs and hand aplasia. In addition, ekymosis and fetal resorption were seen.16.1%, 6.5% and 14% of fetuses were malformed in the I30, II20 and II30 groups, respectively. Also, 11.3%, 4.9% and 12.4% of fetuses in these same groups had limb defects. In the III20 and III30 groups that fetuses used folic acid and drug at the same time, rate of malformations reduced to 1.6% (P<0.05). Conclusion: It is recommended pregnant women not to take acetaminophen atleast a month before pregnancy and in case of taking this drug the folic acid to be accompanied.

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Background&Objective: Abnormal BMI of mother and weight gain play very important role in the outcome of pregnancy. Several researches were done on the correlation between body mass index (BMI) and mother weight gain in pregnancy, and the complications in neonates, like low birth weight and prematurity and mother complications like preeclampsia. This study was performed in order to determine the correlation between body mass index and weight gain during pregnancy, maternal and fetal complications in patient admitted to Deziani hospital in Gorgan, Iran. Materials&Methods: This cross-sectional study was done on 350 pregnant women in Deziani hospital during a year (2002-03). Patients' information's like mother age, pre-pregnancy weight, weight gain during pregnancy and maternal-fetal complications (preeclampsia, PROM, preterm labor and macrosomia) were recorded. After coding, data were analyzed by SPSS and Chi-Square test was used for description. Results: In high BMI women, higher weight gain was seen than normal BMI women. Preterm labor was significantly related with pre-pregnancy BMI (P<0.05) but no relationship was seen between weight gain and preterm labor. PROM and birth weight were significantly related to pre-pregnancy BMI and weight gain during pregnancy (P<0.05). Preeclampsia has significant relationship with weight gain (P<0.05) but not with pre-pregnancy BMI. Conclusion: Abnormal maternal pre-pregnancy BMI and weight gain during pregnancy can complicate the delivery. Low and high BMI and weight gain during pregnancy can contribute with the complications in mothers and neonates.

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Background&Objective: Ectopic pregnancy is a main cause of maternal death and is 10-15% of refered patint to first trimester emergency ward. Due to importance of early detection and prevention of excessive blood loss in Ectopic pregnancy this study designed that evaluated the correlation between vital signs and quantity of hemo-peritoneum and except of traditional vital sign another method with more sensivity can be used in detection of tubal rupture and nessersirily of Emergency surgary. Materials&Methods: This study is a analytic cross sectional design in 105 patients had diagnosis of ruptured ectopic pregnancy in fatemieh hospital. positive predictive value and sensitivity and specifity of pulse rate, BP and shock Index (SI) in correlation to ruptured Ectopic pregnancy and hemoperitoneum evaluated. Results: Hundred five patients were studied (70 ruptured EP and 35 unruptured EP). Mean of shock index in unruptured and ruptured EP was 0.6±0.29 and 0.94±0.22 respectively that was nonsignificant. (p<0.05) Sensitivity of pulse rate, systolic pressure and shock Index (Pulse/SBP) was 17.6%±9%, 32.4 %±10% and 91.4%±6% respeictively. negative predictive value was 34.1%, 38.7 % and 50% respeictively.mean primary Hb had no difference in two group. Conclusion: Normal vital sign alone are poor predictors of ruptured ectopic pregnancy and shock Index (Pulse/SBP) Correlate best with the quantity of intaperitoneal hemorrhage.

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Background & Objective: Rubella vaccine is prepared with live virus thus if it injects during abstinence period, it can cause fetal risks. The aim of study was to evaluate rubella IGM among infants of women who were vaccinated against rubella during 3 months pre-or post-conception (abstinence period). Materials & Methods: This cohort study was done on 253 mothers, including 116 mothers as cases and 137 mothers as controls. The case group inadvertently had received MR vaccine (RA27/3) during abstinence period. The control group selected randomly from similar delivery center that admitted for delivery. The background and confounding factors was matched between the control and case groups. In both groups after delivery, cord rubella IGM was measured by ELISA for serological diagnosis of infant infection. Data was analyzed by Chi-square and T-student tests. Results: The findings showed that the number of positive IGM infant was similar in both groups (One positive IGM in each group). In spite of no significant difference between the case and the control groups, the maximum theoretical risk in this study was 4.392% (RR=1.091 95% CI=0.271-4.392). Conclusion: Although no significant difference was found from the point of infants with an IgM+ serology in two groups, according to the risk ratio obtained in this study, we still recommend vaccination should be avoided during abstinence period.

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Background and Objective: Destructive effects of thyroid diseases in pregnancy and fetal frowth is well established subclinical autoimmune thyroid diseases can double the rate of preterm labor, abortion and postpartum thyroiditis. This study was done to compare thyroid function and autoimmunity derangment in goiterous and non-goiterous pregnant women. Materials and Methods: This case – control study was done on 100 healthy and 100 goiterous pregnant women in Dezyani hospital located in Gorgan, Northern Iran during 2005. Five mililiter of blood sample was obtained from each subject to measure thyroid hormones concentration including T3/ T4/ TSH/ T3 RUP and thyroid autoantibodies (Anti Tg/Anti TPO). Thyroid hormone and auto antibodies were measured using IRMA and ELISA techniques. Results: Thyroid volume was enlargel twice and tripl of its orginal size in 34% and 66% goitrious pregnant women respectively. Mean serum TSH in cases and controls were 1.81+/-1.33 microU/ml and 1.84+/-1.4 microU/ml respectively. The mean of Anti TPO and Anti Tg in cases were 373.91+-197.36 U/ml and 248.80+-70.59 U/ml respectively. The same indecs for controls were 79.52+-63.99 U/ml and 248.80+-70.59 U/ml respectively. In pregnant women with goiter 36% had high Anti TPO and 9% had high Anti Tg, but in control group 16% and 4% of controls had elevated Anti TPO and Anti Tg, respectively. Conclusion: According to thyroid function tests there were elevation of antibody in 20% of the healthy subjects and 45% of the goiterous subjects, therefore it is advisable to measure thyriod function tests accompanied with thyriod antibodies in all pergnant women either with or without goiter in order to prevent feto-maternal disorders.

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Background and Objective: There are some factors including socio-demographic, maternal and nutritional variables reported to influence the growth of children in the first two years of life. The aim of this study was to determine some factors related to undesirable growth of 6 months–2years old children in Tabriz-Iran. Materials and Methods: In this case - control study 233 children with undesirable growth as cases, and 412 children with desirable growth as controls selected in five primary health care centers in Tabriz city in North-West of Iran during 2007. A questionnaire which included some questions regarding demographic characteristics, fertility history, and nutritional status was filled by using face -to - face interview with selected children’s mother. The influence of different factors on undesirable growth was evaluated with a logistic regression model by using SPSS-14 and EPI-2000 software. Results: Having any disease during two monitoring (OR=4.23, 95% CI: 2.95-6.07, P<0.001), type of pregnancy (unwanted) (OR=1.87, 95% CI: 1.20-2.93, P<0.006), gender (girl) (OR=1.51, 95%CI: 1.05-2.17, P<0.025), low birth weight (OR=1.0, 95% CI: 0.99-1.01, P<0.097) and having conflict in the family (OR=1.22, 95% CI: 1.01-1.47, P<0.045) associated with undesirable growth. Conclusion: This study determined having any disease, type of pregnancy, sex of child and low birth weight related with undesirable growth of 6 months –2years old children. Using safe family planning methods and help to reduce unwanted pregnancy, parental training about the nutritional requirements of children particularly during period of disease, is recommended in order to enhance the health of children.

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Background and Objective: Placenta previa (PP) is a common cause of pri-partum bleeding leading to high mortality and morbidity in mothers and neonates. This study was conducted to determine risk factors and outcomes of PP in Golestan province of Iran. Materials and Methods: This case-control study was done on pregnant women admitted for deliverly to the Dezyani hospital of Gorgan, Iran during 2002-07. All PP cases were recruited as case group and 251 non-PP ones were entered into the study as control group. Student t-test and Chi-Square test were used to assess the relationship between variables. Results: In this study out of 33473 pregnant cases, 82 women (0.24%) had PP. The mean (±SD) age of mothers with PP was 28.5 (±6.2) years. There was a significant correlation between PP and delivery method (P<0.05). History of cesarean section was significantly higher in cases than controls (P<0.05). The prevalence of hysterectomy due to PP was significantly higher in women with history of cesarean section (24%) than other ones (5%) (P<0.05). Conclusion: We found a significant relationship between history of cesarean section and hysterectomy due to PP. Therefore, PP should be considered in women with a history of cesarean section.

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Background and Objective: The pregnancy period is very sensitive and complicative stages of life. It has been shown that addictive drugs such as ecstasy (MDMA: Methylene Dioxy Metha Amphetamine) can interfere in this stage. The aim of this study was to assess the effect of Methylene Dioxy Metha Amphetamine administration during pregnancy on reproductive system of BALB/c mice. Materials and Methods: In this experimental study, 10 and 5 female BALB/c mice were randomly selected as cases and controls, respectively. The pregnancy was induced following ovarian hyperstimulation with PMSG and hCG followed by mating with male animals. MDMA (5 mg/kg) and saline was injected intraperitoneally in day 7 and 14 of pregnancy in experimental and controls, respectively. The ovarian structure, as well as uterine tube, uterine horns and body, and vagina were studied histologically using light microscopy 27 days post delivery date. Data analyzed by using SPSS-17 and Chi-Square and Fisher exact test. Results: The rate of primary follicles was decreased from 18.42% in experimental to 33.33% in controls (P<0.05). The rate of mature follicles was significantly increased in experimental mice as compared to controls (P<0.05). The number of atretic bodies was lower in experimental than controls. The cellular alterations were observed in some portions of uterine tubes and uterine horns after ecstasy administration. However, no alterations observed in other parts of reproductive system. Conclusion: This study showed that MDMA cause some structural alterations in the uterine tubes and uterine horns, increase follicular maturation and reduction of follicular atresia in BALB/c mice.

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Background and Objective: Domestic violence can place mother and fetus at risk. This issue can be prevented through education and basic knowledge. This study carried out to determine the frequency and severity of domestic violence in pregnant women referred to health centers in Arak, Iran. Materials and Methods: This cross-sectional descriptive study was done on 400 pregnant women referring in health centers in Arak North-West of Iran during 2009. This research was implemented through questionnaires including the demographic chracteristic aspects of physical violence, emotional, verbal and financial severity and the factors effected violence on pregnant women. Data was analyzed using Chi-Square, one way ANOVA and Tukey tests. Results: The overall prevalence of violence during pregnancy was 34.5%. For this rate, 56%, 48%, 23% and 11% were emotional violence, verbal, financial and physical violences, respectively. Marrige age (P<0.035), partnership lenght (P<0.018), family history of marriage (P<0.001), education (P<0.001), occupation of woman and husband (P<0.001) with the outbreak of violence during pregnancy were significantly associated. Conclusion: This study indicated that the frequency of domestic violence in pregnant women is high, therefore it is sugested women clinic to be established to protect pregnant women suffering from domestic violence during pregnancy.

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Background and Objective: Nausea and vomiting are the most frequent complications in the first trimester of pregnancy. Herbal medicine is among the traditional effective treatments. Ginger and Chamomile are hypothesized to be useful in decreasing the signs. This study was done to determine the effect of Ginger and Chamomile capsules on nausea and vomiting in pregnancy.

Materials and Methods: This triple-blind randomized placebo-controlled trial was carried out on 105 pregnant women in 6-16 weeks of gestational age with a mild to moderate nausea and vomiting, whome referred to the prenatal care clinic in Dezyani hospital and health centers, Gorgan, Northern Iran during 2009-10. Rhodes index questionnaire had been given to all participants to be completed before bed-time for two weeks. In the first week no intervention was done and prescribing the capsules was started the following week. Subjects randomly divided into 3 groups: In group 1, ginger capsules were consumped twice a day for one week, in group 2 twice daily chamomile capsule and in placebo group, glucose capsule was prescribed. Scores were calculated and all data were entered into the SPSS-16 software, analysis was done using variance analysis, Will-Cockson, paired T and Fisher-exact tests.

Results: The mean of Rhodes index before intervention in plasbo, Ginger and Chamomile groups were 12.71±5.88, 10.42±0.76 and 11.19±5.51, respectively. Also, the mean of Rhodes index after intervention in plasbo, Ginger and Chamomile groups were 11.47±6.43, 7.28±3.74 and 5.73±4.32, respectively (P<0.05). Bonferroni test indicated that there is no difference about scor chang (after and before) between Ginger and Chamomile and Ginger and plasbo, but this difference was significant between Chamomile and plasbo group (P<0.05).

Conclusion: This study showed that Chamomile capsule was more effective on nausea and vomiting during pregnancy compared to Ginger.

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Background and Objective: Unwanted pregnancy can have negative impacts on maternal health. The aim of this study was to compare the health status of women with wanted and unwanted pregnancies in Kerman, Iran.

Materials and Methods: This case – control was performed on women with wanted (100 cases) and unwanted pregnancies (100 cases) whom refered to health centers in Kerman, Iran during 2010. The tool for data collection included a demographic questionnaire, short form 36 health survey (SF36) and a researcher-made pregnancy’s  physical health. Validity and reliability of the questionnaires were assessed initially prior to study procedure. Data was analyzed by using SPSS-16, Chi-Square, T Student and Mann-Whitney tests.

Results: Women with unwanted pregnancies had lower scores for physical and mental health, vaccination and supplement consumption, prenatal care and personal health than women with wanted pregnancies (P<0.05). Women with unwanted pregnancies had more complications and high risk behavior compared to unwanted pregnancies (P<0.05).

Conclusion: This study indicated that unwanted pregnancies are accompanied with physical and mental health. Thus, special counseling and extra care measures is recommended during unwanted pregnancies. Pregnancy

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Background and Objective: The incidence of ectopic pregnancy is increasing due to artificial reproductive technology and increasing rate of sexual transmitted diseases. Ectopic pregnancy is the most common cause of maternal mortality in the first trimester and it reduces the chance of future successful pregnancy. Identifying the risk factors can help to reduce the maternal mortality and morbidity due to early diagnosis and on time treatment. This study was carried out to assess the risk factors in ectopic pregnancy in northern, Iran. Materials and Methods: This case control study was carreid out on 150 patients with ectopic pregnancy as cases and 300 women with normal pregnancy as controls. The subjects were selected from teaching hospital in Babol in northern Iran, during 2005-09. The risk factors include history of tuble surgery, ectopic pregnancy, cesarean section, pregnancy with IUD, infertility, assisted fertility with IUI, multiple partener, pre-eighteen years marriages were recorded for each subject by direct interview and file. Data were analyzed using SPSS-16 and Chi-Square and exat Fisher tests. Results: Theraputic assisted fertility with IUI (95% CI: 3.02-185.09, OR: 23.6, P<0.05), previous ectopic pregnancy (95% CI: 1.90-73.94, OR: 8.19, P<0.05) and cesarean section history (95% CI: 1.1-2.6, OR: 1.7, P<0.05) increased the possibility of ectopic pregnancy. There was not significant differnces between pre- eighteen years marriages, infertility history and multiple partener in cases compared to controls. Conclusion: This study showed that assisted fertility with IUI, previous tubal surgery, pregnancy with IUD, previous ectopic pregnancy and cesarean section are the main risk factors of ectopic pregnancy in northern, Iran.

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Background and Objective: Passive smoking during pregnancy increases the risk of pregnancy complications. The purpose of this study was to determine the relationship between self-reported exposure to passive smoking and urinary cotinine level of the pregnant women. Materials and Methods: This cross-sectional study was done on 108 non-smoker pregnant women referred to Arash hospital in Tehran, Iran for delivery during 2010. A questionnaire including smoke exposure during pregnancy was completed for all the participants. Urine samples were collected from the mothers in the delivery room. The urinary cotinine levels was measured by ELISA method. Data were analyzed using SPSS-16, Student t-test, Chi-Square and one-way ANOVA tests. The Kappa test was used to evaluate the variability of mothers which report exposure to passive smoking with maternal urinary cotinine level. Results: The geometric mean cotinine of the maternal urine in the exposed group (27.4±29.96 ng/ml) was significantly higher than the non-exposed group (0.75±2.29 ng/ml) (P<0.05). There was a significant association between maternal reports of cigarette smoke exposure and urinary cotinine (Kappa=96%) (P<0.05). Conclusion: This study indicated that there is a relationship between maternal self-reporting and urinary cotinine level during pregnancy.

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Background and Objective: Electromagnetic waved generated by electronic industries and the increasing use of electrical appliances have led to higher rise in chronic exposure to extremely-low-frequency electromagnetic field (ELF-EMF). This study was done to investigate the effects of low electromagnetic field on mice embryos development. Materials and Methods: In this experimental study, eighty female NMRI mice were super ovulated and coupled with male mated over the night. Next morning the female mice with a vaginal plug were identified as pregnant mice. Animals allocated into 2 groups control group was not exposed to EMF and animals in case group exposed to 50 Hz and amp 1.2 mT EMF the pregnant mice were scarified by cervical dislocation at 24, 72, 81, 96, 110 and 120 hours. Embryos were subsequently obtained from the mice by flashing the fallopian tubule and uterus horn. Data were analyzed using SPSS-13.5, ANOVA and student’s t-tests. Results: The number of 2, 3-4 cells and 5-8 of embryo cells and blastocyst decreased in case group compared to controls, but these reduction were not significant. The number of morula in cases significantly reduced in comparison with control group (P<0.05). The average number of fragmented blastocyst in experimental groups siginficantly increased compared to control group (P<0.05). The number of inner cell mass and trophoectoderm in experimental group significantly reduced in comparison with controls (P<0.05). Conclusion: The exposure of extremely-low electromagnetic field in pregnancy reduces the number of morula, inner cell mass and trophoectoderm.