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One of the effective way to treat and control the neuromuscular organs from injuries of lower limbs in the exercise of backward running. The present research has been set up to determine the effectiveness of this sport and comparing it with forward walking. The aim of this clinical trial is to differentiate between the effectiveness of these two sports on the functional performance tests of lower limbs. To carry out this study 30 normal male has been divided in two groups, in group one forward walking is carried out three 15 minutes session per week for six weeks, and backwards walking has been arranged for group 2 on the same condition. The functional performance tests in this study were vertical jump, single leg hop jump for the distance of 6 meters, in forward and backward running. The findings from this study indicate that there is not meaningful improvement during the six weeks within the 2 different sports. On the basis of these results the 2 procedures of running forward and backward have got the same effect on the increasing the functional performance of lower limbs and both sports can be used active functional rehabilitation.

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Background and Objective: Musculoskeletal injuries are the common causes of disabilities among young patients. This study was done to establish the causes and clinical evidences of bone and joint injuries among young patients in Gorgan, Iran. Materials and Methods: This cross-sectional study was carried out on 600 subjects with musculoskeletal injuries reffered to 5 Azar teaching hospital in Gorgan, north of Iran during 2009. Age, sex, type of initial treatment, location of injury and medical treatment for subjects were completed. Data were analyzed using SPSS-16, Chi-Square and student t-tests. Results: The mean age of subjects was 25±7 years. 83% of subjects were male. In 37% of injured people, time of accident was between 12 to 18 o’clock. The most common causes were car accident (49.7%), workplace injury (15.3%), falling down (10.3%), respectively. Street (38.3%) and road (18.7%) were the location with high accident. Fractures (71.7%), soft tissue injuries (48.3%) and dislocation (8.7%) were the most common injuries. Upper and lower limb were the most common in injury and fractur, respectively. Conclusion: This study showed that young men are more prone to accident and occupation injuries.

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Background and Objective: The human anthropometric characteristics are surveyed in anthropology. Anthropology is used in archeology, physiotherapy, rehabilitation and legal medicine. This study was carried out to evaluate the anthropometric characteristics of upper limb in Iranian and Pakistani subjects. Method: This descriptive - analytic study was performed on 300 resident’s adult subjects (180 males and 120 females) in Qazvin, Iran and 356 residents (181 males and 175 females) in Dera Ghazi Khan, Pakistan. Anthropometric characteristics of upper limb were measured in an anatomical position. Results: The mean±SD of arm length was 36.8±2.37 CM and 28.1±2.44 CM, in Pakistani and Iranian males, respectively, this difference was significant (P<0.05). The Mean of forearm length, hand length and hand width in Iranian men and women were non-significantly more than Pakistani subjects. Conclusion: Anthropometric characteristics of upper limb of Iranian are higher than Pakistani subjects, but this difference only in arm length of men was significant.

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Background and Objective: Cyclooxygenase 1 and 2 activities on arachidonic fatty acids of cell membrane produces prostaglandins which involved in inflammatory processes. This study was done to evaluate the effect of hexanic and hydroalcoholic extract of Cannabis sativa flowers on inflammatory paw edema in rats. Methods: In this experimental study, 56 male Wistar rats were allocated into the control, sham, sodium salicylate (300mg/kg/bw) and hydroalcoholic extract of heated flowers in 1, 10 and 50 mg/kg/bw, hydroalcoholic extract of unheated flowers in 50mg/kg/bw and hexanic extract of heated flower in 50mg/kg/bw, intraperitonally. 30 minutes after injection, inflammatory edema volume due to sub plantar injection of formalin (0.05 ml, 2.5%) measeared using plethysmometric method. Results: Intraperitonally injection of 50mg/kg/bw, of hydroalcoholic and hexanic extracts of heated flowers significantly reduced in inflammatory paw edema induced by formalin (P<0.05). Also, 50mg/kg/bw, hydroalcoholic extract of unheated flowers reduced the inflammatory paw edema in comparison with heated extracts (P<0.05). Conclusion: Hydroalcoholic extract of heated flowers decreased inflammation-induced paw edema in dose-dependent manner. The extract of unheated flowers, leads to more reduction of the inflammatory paw edema in comparison to heated flower extract, it can be due to carboxylated cannabinoid present in the hydroalcoholic extract of unheated flowers.

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Background and Objective: Diabetic neuropathy is one of the most prevalent complications of diabetic micro-vascular that causing sensory loss of the legs, pain and disorder in proprioception after destroying of the lower limbs nervous system afferents consequently leads in balance disorder. This study was done to determine the effectiveness of reflexology and Yumeiho massages on lower limb pain and keep balance in females with diabetic neuropathy.

Methods: In this semi-experimental study, thirty-four patients with diabetic neuropathyin lower limb non-randomly divided into reflexology, Yumeiho and control groups. Pain and balance were measured using the visual analogue scale, Sharpened Romberg and berg test respectively that were completed at baseline and after 6 weeks. Six weeks of Yumeiho and reflexology massaging were applied over 3 days in week for 30 minutes on the experimental groups.

Results: Pain and balance of patients singnificantly improved in reflexology and Yumeiho groups in compared to controls (P<0.05). There was no significant difference between reflexology and Yumeiho groups.

Conclusion: Reflexology and Yumeiho massages have a same impact on the pain rate and balance of lower limb in women with diabetic neuropathy.

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Background and Objective: Control of postoperative pain is one of the most important stages in the recovery of patients after surgery. This study was done to compare the effectiveness of combined Ondansetron and Apotel on the post-operative pain after surgery of upper limb fractures.
Methods: This double blind clinical trial study was done on 50 individual (41 male and 9 female) with upper limb fractures referring to 5 Azar hospital in Gorgan northern Iran during 2017. Patients were assigned (block randomization) into control and intervention groups. After the end of operation in the recovery phase, both groups received pain PCA (Patient Controlled Analgesia). In control group, the pain pump consisted of 2 grams of Apotel and in the intervention group; the pain pump consisted of 2 grams Apotel and 8 mg of ondansetron. Visual Analogue Score (VAS) was evaluated in both groups after surgery for 24 hours. Pain score of patients compared in the 2 groups during the 3 time intervals after surgery.
Results: 4 hours after upper limb fracture surgery, the mean pain was significantly decreased in the intervention group (3.20±0.707) compared to control group (3.64±0.569) (P<0.05). 12 hours after upper limb fracture surgery The Mean pain, in the intervention group (1.88±0.927) was significantly reduced in compare to control group (2.64±1.186) (P<0.05). 24 hours after upper limb fracture surgery, The Mean pain was significantly reduced in the intervention group (1.40±0.645) in compare to control group (2.08±0.997) (P<0.05).
Conclusion: This study showed that administration of compination of Apotele and Ondansetron in post-operative pain of upper limb fractures is effective than apotele alone.

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Background and Objective: Proprioceptors of the plantar surfaces of the foot have less efficiency and the stimulation and reinforcement of them may be lead to reduction of falling risk. One of the methods to reinforce proprioceptor receptors in these individuals is using textured foot orthoses. The aim of this study was to evaluate the effect of textured foot orthoses on frequency spectrum of lower extremity muscles, stance time and comfort in individuals over age of 55 years during walking.
Methods: This quasi-experimental study was done on the 14 females and 14 males age ranged of 56-70 years with the ability to walk independently and with physical and mental health status. Subjects were compared during five conditions including without foot orthoses and using four foot orthoses (including small and large foot orthoses with two types of flexible and rigid), flexible and rigid large textured foot orthoses. The 8 electrodes were located on tibialis anterior, medial gastrocnemius, vastus medialis, vastus lateralis, biceps femoris, semitendinisus, gluteus, and erector spinae in 3 lumbar vertebrae region muscles.
Results: Frequency content of tibialis anterior and vastus medialis was significantly increased in males than female (P<0.05). Vastus medialis frequency during walking with large foot orthoses was more than walking without foot orthoses (P<0.05). The comfort level was different during flexible large textured foot orthoses condition compared with flexible small textured foot orthoses condition (P<0.05). The stance time was not significant between all conditions.
Conclusion: Increased frequency content of the vastus medialis muscle can increase the absorption and decrease the vertical loading rate imposed on the foot, which in turn reduces the risk of injury of the lower limb in older adults.

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Background and Objective: Multiple sclerosis (MS) is one of the most common diseases of the central nervous system. MS is more common among women. Gait pattern dysfunction is a relevant symptom in these patients. This study was conducted to compare the electromyography activity of selected lower extremity muscles and the ellipse area of center of pressure during unplanned gait termination in female patients with multiple sclerosis and healthy individuals.
Methods: This case-control study was performed on 10 female patients with MS (classified based on the EDSS scale) and 10 healthy subjects matched for height, age and weight. Electromyography activity of rectus femoris (RF), vastus medialis (VM), vastus lateralis (VL), biceps femoris (BF), semitendinosus (SM), gastrocnemius medius (GM) and tibialis anterior (TA) and center of pressure (CoP) recorded using foot pressure system during unplanned gait termination. Subjects were instructed to stop, as soon as possible, in response to an auditory cue delivered when the heel strike phase accidentally.
Results: Vastus Lateralis muscle activity was significantly higher in able-bodied group than patients (P<0.05), whereas in the patient group gastrocnemius medius muscle activity increased significantly (P<0.05). Also, the ellipse area of center of pressure significantly reduced in MS group in compered to able-bodied group (P<0.05).
Conclusion: Increased gastrocnemius medius muscle activity in MS patients may be due to their attempt to slow down the displacement of the center of mass to limit the tibia forward translation consequently, attempting to control balance as a strategy to limit the ellipse area of center of pressure to prevent fall.