---

Background&Objective: Due to side-effects of diabetes mellitus in pregnancy, the rapid diagnosis and its treatment is very important. The aim of this study is to determine gestational diabetes mellitus (GDM) incidence in pregnant women. Materials&Methods: This survey is an analytic cross sectional study that evaluated 401 pregnant women in Babol Obstetrics Clinic. A Glucose Challenge Test (GCT) was done for all of the high risk women for diabetes in the first trimester and for other pregnant women in 24-28 gestational weeks. If GCT was positive (Blood sugar>135 mg/dl one hour after oral administration of 50gr Glucose), then a Glucose Tolerance Test (GTT) was done. For women with a positive GTT, the diagnosis was GDM. Results: In 401 pregnant women with a mean age of 24.69±5.31 four patients had overt diabetes (1%). In another 397 women, a GCT was done and 44 women (11% of all patients) had a positive GCT and 19 patients (4.7% of all patients) had GDM of those with GDM 26.3% need insulin therapy in addition to a diabetic diet. We noted there was also a positive relation between age and impaired GCT (P<0.05). Conclusion: GCT is recommended as screening test in 24-28 gestational weeks for all pregnant women.

---

Background and Objective: Gestational diabetes is affected 3-12% of women and occurs at the final stage of second trimester. This study was done to determine the fructosamine and glycated hemoglobin level in pregnant women with abnormal glucose challenge test. Methods: This case – control study was carried out on 96 pregnant women with glucose challenge test (GCT)>140 mg/dl as cases and 96 pregnant women with GCT<140 mg/dl as controls. The serum fructosamine and glycated hemoglobin determined using ELISA and chemical methods, respectively. Results: In pregnant woman with abnormal GCT, there was a significant correlation with glycated hemoglobin and fructosamine. The glycated hemoglobin correlation was more significant compared to fructosamine (0.63 to 0.24). There was not significant correlation between GCT with fructosamine and glycated hemoglobin in individuals with normal GCT. Conclusion: The measurement of glycated hemoglobin is more accurate than fructosamine in pregnant women with abnormal glucose challenge test.