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Background and Objective: Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease, leading to progressive disability, reduces daily activity and function and emerges with a wide range of physical symptoms. This study was done to determine the effect of relaxation on the physical symptoms in women with Multiple Sclerosis. Methods: In this clinical trial study, 50 patients with MS were randomly divided into relaxation and control groups. In the interventional group, Jacobson and Benson method was performed for 4 weeks, twice a week for 40 minutes and patients in the control group were received only care and routine medical treatment. Data was collected via fatigue severity scale (FSS), numerical rating scale (NRS) before, immediately after and two months after intervention. Results: The mean severity of fatigue score, before, immediately and two months after the intervention were not the same and time trends was effective on severity of fatigue score (P<0.05). The mean of fatigue score were significantly reduced in intervention group (immediately and two months after intervention) in compared to pre-intervention. The mean severity of pain score ,before, immediately and two months after the intervention were not the same and time trends was effective on mean severity of pain score (P<0.05). The mean intensity of pain score over time in the relaxation group non-significantly reduced in compared to the control group. Conclusion: Relaxation technique is effective as a low-cost, safe and easy method to reduce fatigue and pain in patients with MS.

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Background and Objective: Muscles fatigue around the joint can altere the movment pattern and incrasing the risk of muscle damage. This study was done to determine the effect of hip abductor muscles fatigue on plantar pressure characteristics during stance phase of gait.

Methods:  This quasi-experimental studywas done on 22 males with age ranes of 15-21 years olds. Hip abduction protocol with 50% of one-repetition maximum was used to induce hip abductor muscles fatigue. Average pressure, plantar peak pressure, step duration and the plantar contact area in both feet distribution were collected using before and after the fatigue protocol during gait.

Results: Despite the relative reduction in average pressure, contact area and step duration and plantar increase in peak pressure after abductors fatigue, but these differences were not significant.

Conclusion: This study showed that the hip abductor muscles fatigue can not alter plantar pressure characteristics during stance phase of gait.

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Background and Objective: Acute ischemic preconditioning improves exercise performance. This study was done to determine the effect of four weeks of ischemic preconditioning on vascular grow factor (VEGF), lactate metabolism and fatigue indices.
Methods: In this clinical trial study, twenty inactive young men were randomly divided experimental (n=10) and control (n=10) groups. Subjects in experimental group perceived ischemic preconditioning (consisted of four 5-minute cycles of ischemia, followed by five minutes of reperfusion) for four weeks prior training. Blood samples were taken in the rest in order to measuring of VEGF. 48 hours prior and after the last intervention session, subjects performed an anaerobic Wingate test and rating the perceived exertion immediately and blood lactate were measured before, immediately, 5, 10 and 15 min after of Wingate test.
Results: 4-week IPC treatment significantly increased VEGF in compared to control group (138.2±8.2 vs 160.1±10.3) (P<0.05). Rating of perceived exertion (6.4±0.5 vs 6±0.1) and lactate accumulation in 15 min after exercise was significantly lower in experimental group in compare to controls (4.1±0.8 vs 5.6±1.2) (P<0.05). There was no significant difference between groups for power output (745.2±131.6 vs 769.7±148.6) and fatigue index (50.58±7.2 vs 46.2±11.8).
Conclusion: Four weeks of ischemic preconditioning increase VEGF and reduce rating the perceived exertion and blood lactate after intensive exercise in inactive young men.

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Background and Objective: Multiple sclerosis (MS) is one of the most common progressive neurological diseases affecting the motor pathways leading to muscle fatigue. This study was done to evaluate the effect of eight weeks of aquatic exercises on fatigue, balance and functional training in male patients with multiple sclerosis.
Methods: This clinical trial study was done on 15 men with multiple sclerosis in Zahedan, south-east of Iran. The subjects selected by available and purposeful sampling method participated in research. After primary screening and reconnaissance person of bona fide, subjects randomly divided into intervention group (n=8) with average age 42.62±6.67 height 171.87±2.47 weight 69.62±12.39 and control group (n=7) with average age 30.28±7.11, height 171.57±8.05 weight 66.68±17.26. During study the patients used and follow medicinal drugs according to prescription. Subjects in interventional group were received aquatic exercises program. Aquatic exercises program consisted of 8 weeks, 3 sessions per week. The level of fatigue, balance and functional movement respectively evaluated with fatigue assessment battery for MS, Y balance and side hop jump tests.
Results: The mean of functional movement was significantly increased in interventional group in comparison with controls (P<0.05). The mean of fatigue was significantly reduced in interventional group compared to controls (P<0.05).
Conclusion: Eight weeks of aquatic exercises improves functional movement and reduce fatigue in male patients with multiple sclerosis.

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Background and Objective: Overexposure to electromagnetic waves produces by computer cause health disorders by users. This study was performed to determine the employer's exposure risk to electromagnetic fields from monitors of computers in north of Iran
Methods: This descriptive-analytical study was performed on 100 of computers using by 100 employee users (69 males and 31 femals) with the mean age of 40.83±7.37 in Gomishan county, Golestan province in north of Iran during 2018. The intensity of the magnetic and electric field caused by computers was measured at 30, 50 and 60 cm intervals and in four directions from the front, back, right and left side of the monitor using SVENSK standard method. The intensity of fields was measured by TM-190 instrument. Data were compared with OEL (Occupational Exposure Limit), MPRII and TCO (The Swedish Confederation of Professional Employees). The NIOSH (National Institute for Occupational Safety and Health) standard questionnaire was used to assess the side effects of working with computers. The health problems in employee users were recorded.
Results: The mean±SD of the intensity of the electrical waves was 103.63±33.62 v/m that was less than the standard values. The mean±SD of the intensity of the magnetic waves was 0.1±0.09 mA/m that was higher than the TCO, MPRII standard values and less than OEL. The maximum magnetic-field invasion from the standard range with an average of 157.04 mA/m is on the front of the monitors, at a distance of 30 cm and the lowest of them with a mean of 19.2 mA/m for the off-mode computer and at a distance of 60 cm from the mantle. There was a significant difference between the time of working with computer in the day with burning eye, headache and eye fatigue. There were no significant difference of clinical symptoms in men and women and fatigue syndrome.
Conclusion: The electrical waves of monitor of computers were lower than standard limit in all studied conditions, but the magnetic waves were much higher than standard limit.

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Background and Objective: With the increase in the spread of COVID-19, mental health consequences such as fear, anxiety, and depression have become prevalent. This study aimed to investigate the predictive role of fear of COVID-19 and quarantine fatigue on depression in congenital heart disease patients during the pandemic.
Methods: This descriptive-analytical study was conducted on 105 patients with congenital heart disease (6 men and 99 women) who were referred to Shahid Rajaee Hospitals and Tehran Heart Center during 2021-22. Data were collected using a depression scale, a fear scale for COVID-19, and a quarantine fatigue questionnaire.
Results: The results showed that 28.6% of patients with congenital heart disease experienced mild depression, while 7.6% had severe depression. Quarantine fatigue was found to be mild in 43.8% of patients. Additionally, fear of COVID-19 (r=0.195, P=0.001) and quarantine fatigue (r=0.617, P=0.001) were significantly correlated with depression in congenital heart patients.
Conclusion: Fear of COVID-19 is related to depression caused by coronavirus and quarantine fatigue in patients with congenital heart disease.
 

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Background and Objective: Fatigue is considered one of the factors effective in changing the electrical activity of muscles so that it is directly linked to increasing the potential of muscular injuries and functional decline in various stages of sports. The present study was conducted to evaluate the frequency of electrical activity of lower limb muscles before and after fatigue during running in individuals with a history of coronavirus disease 2019 (COVID-19) compared to healthy individuals.
Methods: This quasi-experimental research was conducted on 14 women with a history of COVID-19 over the past two months (the experimental group) and 14 women without a history of COVID-19 (the control group) with an age range of 18-30 years using the convenience sampling method in the city of Ardabil. The fatigue protocol started using a sophisticated treadmill at a speed of 6 km/h, and the treadmill speed was accelerated by 1 km/h every 2 minutes. The Borg’s Rating of Perceived Exertion (RPE) 6-20 Scale was used to determine the participants’ final moment of fatigue. A steady-state running fatigue protocol ended at a score higher than 17 on the Borg’s RPE 6-20 scale or 80% of maximum heart rate. Electromyography data were analyzed using the data LITE biometrics software before and after the fatigue protocol.
Results: There was a statistically significant increase in the frequency of the electrical activity of the vastus lateralis (VL) muscle between the post-test of the control group and the experimental group (d=0.410, P=0.035). The pretest-posttest difference of the frequency of electrical activity of the VL muscle after fatigue compared to before fatigue during the loading response phase during running had a statistically significant increase in the experimental group than in the control group (d=0.602, P=0.016). The frequency of the activity of the semitendinosus muscle increased after fatigue compared to before fatigue during the mid-stance phase of running (d=0.261, P=0.005). The impact of fatigue on the frequency of the activity of the VL muscle during the push-off phase of running was statistically significant (d=0.140, P=0.049). The frequency of the activity of the VL muscle increased after fatigue compared to before fatigue during the push-off phase of running in the experimental group.
Conclusion: The increased electrical activity of the lower limb muscles in various phases of running after fatigue in individuals with a history of COVID-19 can be attributed to decreased neuromuscular coordination.