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Background&Objective: This study is designed to deteremine the sex differences in volume and surface anatomical parameters in the cingulate cortex of the left cerebral hemispheres in healthy right - handed subjects. Materials&Methods: This cross - sectional descriptive study was performed on 72 human brains (38 males, 34 females). The brains belonged to right - handed subjects who had died of non - neurologic causes. The age of males and females was similar. The brains were removed from the cranium no longer than 24 hours postmortem and were fixed in 4% formaldehyde solution. The right hemisphere of each brain was used for neuropathologic examinations (to confirm the health of the brain) and the left one was used for stereologic analyses. The estimation of the volume, surface areas, and thickness of the cingulate cortex was performed on photographs of 5 mm serial coronal sections of the left hemispheres using unbiased stereological methods (with point and linear grids). The results were analyzed by t- student test. Results: The volumes of the left cingulate cortex in males and females were 10.923.06 and 10.52.30cm3, respectively. The outer surface area was 43.8710.73 cm2 in males and 43.748.68cm2 in females. The inner surface areas in males and females were 34.8711.56 and 36.558.08cm2, respectively. There was no significant difference between two sexes in the volume and surface areas of the left cingulate cortex. The mean thickness of the left cingulate cortex in males and females were 2.880.5 and 2.510.3mm, respectively. The mean thickness of the left cingulate cortex in females was 12.85% smaller than males (P<0.05). Conclusion: Although the volume and outer and inner surface areas of the left cingulated cortex are similar between two sexes, the cortical thickness of this area in healthy right - handed females is significanlty smaller than males. The functional significance of these sexual differences and similarities in human brain is not clear. However, scientists must be aware of them in their morphometrical studies on human brain.

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Background&Objective: Vibrio species are oxidase positive, gram negative bacilli that predominantly reside in surface waters such as lakes , rivers. They cause predominantly intestinal diseases as well as a few extra-intestinal complications. Vibrio-related diseases often rise during natural disasters such as floods. Vibrio cholerae cause cholera in humans. In this study, the occurance of Vibrio cholerae in the surface waters of Golestan province, was investigated. Materials&Methods: The APW and TCBS agar culture media were used for primary isolation of Vibrio cholerae and the exact species identification were done by performing the following tests oxidase reaction, growth in 0% , 1% , 3% , 6% salt solution, lysine and ornithine decarboxylase, Arginine dehydrolase, ONPG and VP test, simmon citrate, bile esculin, indole, CAMP reaction, string test and specific antisera to V.cholerae 01. to confirm the findings, the special antiserum Ogawa and Inaba, were used. Results: We were able to isolate 42 Vibrio spp. from a total of 54 water samples collected. The species included 35 non-01 V.cholerae (84.2%), 2 V.mimicus (2.63%) and 5 V.cholerae 01 (13.1%) isolat. Conclusion: This study confirmed the existence of Vibrio cholerae 01 in 9% of samples from surface waters of Golestan province.

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Background&Objective: In recent century, progress of technology and hygiene has caused improvement of human life. But factors such as car accidents and braws cause body damages. Due to absence of about the prevalence of jaw and face fractures proper pattern and related damages in Golestan province, this study was done to determine the pattern of jaw and face fracturs in 5th Azar hospital in Gorgan – Iran (2003-04). Materials&Methods: In a 3-years prospective study (2003-04), 221 patients in referral hospital in Golestan province were evaluated and data about demography, etiology, related damages and therapeutic procedures inserted in informational forms and extracted data was analysed by SPSS 11.5 software. Results: In this study 84.1% and 15.9% of patients were male and frmale, respectively and most of them were 21 to 30 years old. The most common causes of fractures of jaw and face in these patients consist of driving accident (72.8%), falling down (15.4%) and major trauma (11.8%). In accidents, motor accidents were the commonest cause (60.9%). Mandible bone was the commonest site of fracture (77.8%) and trauma to the skull and nervous tissues was the most common accompaniment damage. Open reduction was the main therapy in these patients. Death was not seen in this study at all. Conclusion: This study showed that driving accidents, specially motor accidents are the most common causes of fractures of jaw and face. Therefore , emphasis on observation of driving regulations and use of life belt and helmet is very important.

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Background and Objective: Superficial pigmented lesions are the most common complaint in dermatology. This study was done to assess the therapeutic effect of cryotherapy in facial lentigo and junctional nevus. Materials and Methods: In this descriptive study, 100 cases of flat-pigmented lesions with diameters up to 2 mm and after taking a photograph with USB microscope M2 (Scalar) treated with one freeze thaw cycle with liquid nitrogen through an applicator for 2 second in Imam Reza hospital, Mashhad, Iran during 2004-05. The patients were visited 3 times again through 3 successive months. According to the decrease in color of the lesion, patients were divided into 4 groups: sever pigmentation, no response, partial (>50% color loss) and complete response (<50% color loss). Data were analyzed using SPSS-11.5 and Wilcoxon test. Results: 96% of our patients were female and 4% were male. Mean age was 30±11.7 years. Based on Fitzpatrick criteria fifteen patients had type 2, fifty had type 3 and 35 had type 4 skin color. After the period of 3 months follow up, 6% of the patients completely healded, 58% had partial response, 31%with no response and 5% develop hyperpigmentation. Response in patients with type 2 Fitzpatrick skin color was clinically better than type 3 and 4 but this difference was not significant. Conclusion: Cryotherapy is considered as a simple, cost effective and safe therapeutic regiment in treating of 64% facial pigmental lesions.