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Diabetes mellitus is a common metabolic disorder that is associated with long-term complications of various organs, such as cardiovascular system. This study is about evaluation of myocardial function and determination of related cardiovascular factor in type 2 diabetic patients who referred to diabetes clinic of 5th Azar Hospital from 200 patients who referred to the clinic, 48.5% had diastolic and 29.5% had systolic dysfunction. Related factors with both diastolic and systolic dysfunction of diabetic patients are: HbA1c level (Control of diabetes), duration of diabetes and hypertension. This investigation shows that: Incidence and severity of systolic and diastolic dysfunction in type 2 diabetic patients are related to metabolic state and quality of diabetic control. Incidence of hypertension increase in diabetic patients, and hypertension is an important risk factor in diastolic and systolic dysfunction. Diastolic dysfunction is more common than systolic dysfunction in diabetic patients. Intensive control of blood Glucose level lead to decreasing the incidence of coronary artery disease in diabetic patients. We suggest, intensive control of blood Glucose level, treatment of hypertension, regular cardiovascular evaluation in diabetic patients and screening test for early diagnosis of diabetes in high-risk population should be taken under consideration.

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Kawasaki disease is a systemic vasculitis of unknown etiology. The most significant sequela of acute Kawasaki disease are related to information of small to medium sized arteries and, in particular, the development of coronary artery dilation and aneurysms (CAA). The aim of this study was to assess the cardiovascular complications of Kawasaki disease in Iran. The studied population consisted of 54 patients who were diagnosed to have Kawasaki disease and referred for cardiac evaluation. There were 30 boys and 24 girls, aged between 5 months and 13 years (Mean 3.9 years). All patients except 3 had received standard treatment with high-dose Aspirin and intravenous ? Globulin (IVGG). All patients were evaluated by physical exam, chest X-ray, ECG and echocardiography (ECHO). Abnormal cardiac findings included: Cardiomegaly in 4 (7.6%), ECG changes in 4 (7.6%), Mitral regurgitation in 3 (5.5%) LV dysfunction in 2 (3.7%), pericardial effusion in 4 (7.6%) and coronary artery dilatation in 5 (9.2%). Conclusion: 1) Kawasaki disease and its cardiovascular complications are not uncommon in Iran. 2) Coronary artery involvement is a major problem. 3) IVGG therapy reduces the risk of cardiac complications. 4) ECHO is a valuable tool in acute phase and follow-up period.

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Background&Objective: Prolongation of QRS duration particularly in Left bundle Branch Block (LBBB) is commonly associated with many cardiac diseases. Electrocardiographic study of QRS duration and electrical axis may be predictors of sever LV systolic dysfunction. Materials&Methods: In this prospective Study conducted in cardiac ward CCU and out- patient clinic of Sh. Beheshti hospital in Babol (1999-2001), 150 patients with diagnosis of LBBB divided to two groups (one QRS≥0.16 second and the other with QRS<0.16) second . Then relationship between QRS- duration, Left axis deviation and echocardiographic LV ejection fraction analysed. Results: There wasn’t significant correlation between ages, gender, and type of cardiac disease with ejection fraction among patients with LBBB. The mean ejection Fraction in the patients with a QRS duration0.16 second (n=19) was significantly lower than the mean ejection fraction in the patients with a QRS duration<0.16 second (n=131) (P<0.05) Presence of Left axis deviation associated with LBBB did not have added predictive value and was not significantly correlated with Ejection Fraction. Conclusion: As conclusion, the QRS duration 0.16 second in the presence of LBBB has a significant inverse relation with Ejection Fraction and is a simple and appropriate marker of significant left ventricular dysfunction.

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Background and Objective: Congenital anomalies are one of the major causes of neonatal mortality. Congenital heart disease (CHD) is the most common birth defect world wide, and recent studies about CHD have reported congenital heart disease approximately is about one percent of all live births. This study was done to determine the frequency of congenital heart disease using ecocardiography in patients with extra-cardiac anomalies in Gorgan peadiatric center in north of Iran.
Methods: In this descriptive study, 55 girls, 84 boys a total of 139 patients were in the age range of birth to 12 years of age whom have referred to Taleghani Teaching and Medical Center in Gorgan during 2012-17. 139 cases of congenital heart disorders with echocardiographic report sheet in their medical record were evaluated. Information of patients including age, sex, ethnicity, type of extra-cardiac, anomalies, cardiac anomalies (simple, complex and ductal anomalies), cardiac murmur status, and clinical symptoms were extracted from their medical records.
Results: From of total of echocardiography, 139 patients (88.5%) were affected by congenital heart disease. The anomalies were included of 88 cases (56.05%), 48 cases (31.21%), 2 cases (1.27%) simple, complex anomaly and ductal dependent anomaly respectively. The other disorders accompanied with congenital heart diseases were 17 cases (12.2%) with cleft palate, 4 cases (2.9%) with congenital diaphragmatic hernia, 8 cases (5.8%) with closed anus, 52 cases (37.4%) with Down syndrome, 4 cases (2.9%) with Turner syndrome, 4 cases (2.9%) with ileum atresia, 11 cases (7.9%) with Esophageal atresia, 7 cases (5%) with Hirschsprung's disease, 6 cases (4.3%) with urogenital anomalies and 26 cases (18.7%) with other extra-cardiac abnormalities.
Conclusion: Down syndrome and cleft palate are among the highest prevalant anomalies with congenital heart diseases.

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Background and Objective: Echocardiographic measurement of ventricular elastance is essential for evaluating cardiac function. With the technological advancements in echocardiography devices, assessing fetal heart function has become more accurate. Ventricular elastance reflects ventricular function, while arterial elastance measures ventricular afterload. Ventricular-arterial coupling demonstrates the interaction between the ventricle and artery. This study aimed to estimate ventricular end-systolic elastance, arterial elastance, and ventricular-arterial coupling using a non-invasive echocardiographic method.
Methods: This descriptive-analytical study was conducted on 67 fetuses with a gestational age of 19-24 weeks (38 female fetuses and 29 male fetuses) and 43 infants aged 10-60 days (25 female and 18 male) referred to the cardiac echocardiography clinic of the Children's Medical Center over a period of 14 months. Mothers and infants were healthy, and there was no structural heart disease in the fetuses and infants. Those with abnormal rhythm, a vague view, and an unfavorable quality of Doppler signal were excluded. Ventricular end-systolic elastance (Ea), arterial elastance (Ees), and ventricular-arterial coupling (Ea/Ees) were compared in fetuses with the calculated values in newborns. An estimation of the normal value for ventricular and arterial elastances and ventricular-arterial coupling in healthy fetuses and newborns were obtained.
Results: The mean arterial elastance of fetuses and newborns was determined as 84.4±20.04 mmHg/ml and 12.6±2.88 mmHg/ml, respectively (P<0.05). The mean ventricular elastance of fetuses and newborns was 88.5±20.49 mmHg/ml and 15.07±2.89 mmHg/ml, respectively (P<0.05). Fetal and newborn ventricular-arterial coupling were calculated as 0.96±0.14 mmHg/ml and 0.84±0.13 mmHg/ml, respectively (P<0.05).
Conclusion: The amounts of arterial and ventricular elastance and ventricular-arterial coupling in fetuses were significantly higher than infants and decreased with increasing age.