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Background and Objective: The coronavirus disease 2019 (COVID-19) has shown an increasingly rapid progression in individuals with underlying diseases or comorbidities, frequently culminating in mortality. This study was conducted to compare certain risk factors associated with mortality due to COVID-19 in patients at Shohadaye Kargar Hospital in Yazd.
Methods: This descriptive study was conducted on 120 surviving (recovered) polymerase chain reaction (PCR)-positive COVID-19 patients (55 males and 65 females) with a mean age of 52.8 ± 18.88 years and 60 deceased PCR-positive COVID-19 patients (34 males and 26 females) with a mean age of 75.4 ± 15.4 years at Shohadaye Kargar Hospital in Yazd, Iran during 2019-2020. Census sampling was performed on all confirmed positive cases of COVID-19. Variables including age, gender, cigarette use, presence of diabetes, hypertension, pulmonary and cardiovascular diseases, and malignancies, which were collected in Yazd Province by the Provincial Coronavirus Committee, were evaluated.
Results: The variables of gender, cancer, cigarette use, asthma, and deep venous thrombosis (DVT) did not show any statistically significant differences between the recovered and deceased groups. The variables of diabetes, hypertension, ischemic heart disease, chronic obstructive pulmonary disease (COPD), and age showed statistically significant differences between the two groups (P<0.05).
Conclusion: Advanced age and the presence of hypertension and diabetes are considered risk factors in COVID-19 patients.

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Background & Objective: Burning is a general health problem and is also a global injury as well as a very serious sanitary issue in industrial and developing countries. In its severe form, burning can claim lives. It seems essential in every society to analyze burning, to study the causes of burning, treatment outcomes and the death rates, etc. to find proper preventive measures. Materials & Methods: In this cross-sectional study, the medical records of all patients who were hospitalized and finally deceased during the years 2002 and 2004 in Zare' teaching hospital, Sari, were examined. Some variables including the age span average, the degree and percentage of burning, patients' residence, gender, the cause of burning (i.e. boiling water, fire, acids and explosives), average hospitalization period, surgery and also the abundance of self – burning attempts were examined. Results: This study indicate that during these 3 years the total number of those who died from burns was 506 (23.4%). The residential places were in Mazanderan province (41.7%), Golestan province (41.4%), and Gilan province (10.2%). The abundance of burning ranges as below: The 2 and 3 degree of burning at 91.8%. Regarding the percentage of burns, 31.7% of abundance pertains to burning at 90% and more. The greatest external causes leading to burns are petrol, gas, and gas oil at 57.9%. Also, the percentage of burns does not have much influence on death rate among 50 – year – olds and older people. Conclusion: This study indicated that the importance of death between burned patient in special sex and age. To establish hospitals, some issues must be considered as: distance, transportation, route dangers, characteristics of area, existing epidemiological survey, and finally the epidemics and event statistics.

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Background and Objective: Anesthetic agents effect on pregnancy in operating room personnel is a challenge in anesthesiology. This study was carried out to determined pregnancy complications among hospital operating room personals in Fars province – Iran.

Materials and Methods: In this case-control study, 122 women working in operating rooms of governmental Fars province hospitals during their pregnancies with different jobs considered as case group. 122 women working in internal and pediatric wards considered as control group. The history of pregnancy complications including infertility, abortion, preterm labor, fetal death, neonatal death and low birth weight obtained using questionnaire. Data were analyzed using SPSS-15 software and Chi-Square test.

Results: The incidence of abortion was 19.8% and 16% in case and control group respectively, this difference was not statistically significant. Infertility was significantly higher (8.2% versus 2.5%) in case group than control group (P<0.05). No significant differences in incidence of preterm labor, fetal death, neonatal death and low birth weight were seen between two groups.

Conclusion: This study showed that the incidence of pregnancy complications is similar between women working in operating room and those working in other hospital wards but the prevalence of infertility is higher in operating room personnel than those of other wards.

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Background and Objective: Considering the role of the hippocampus in memory, this study was done to evaluate the effect of 3-4,methylenedioxymethamphetamine on CA1 hippocampal neurons in male rats. Materials and Methods: In this experimental study 18 sprague dawley male rats (200-250g) were randomly allocated into three groups as follow: control (intact), control sham and experimental groups. Sham and experimental groups were received normal salin (1 cc) and MDMA10mg/kg IP for 7 days, respectively. Following transcardial perfusion by paraformaldehid 4%, structure and ultrastructure of right CA1 hippocampus were assessed by crysel violet staining and electronic microscope. Data were analyzed using SPSS-16, ANOVA and Tukey tests. Results: There was no significant difference between control (mean=210±40.38) and sham groups (mean=199±38.7) in neuron density. Neuron number decreased significantly in experimental group (mean=98±25.4) in compare to control and sham groups (P<0.001). There was no ultrastructural abnormality in control and sham groups. Finally, ultrastructural changes with apoptosis characterized by mitochondrial cristae reduction, distribution of nuclear chromatin and loss of cytoplasmic organelles in MDMA groups. Conclusion: This study shows that MDMA administration can stimulate the cell death with apoptotic pattern in hippocampus.

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Anomalous coronary artery origin is a rare clinical entity with varied clinical outcomes ranging from asymptomatic to sudden cardiac death. The incidence of anomalous origin of left coronary artery arising from the right coronary cusp is 0.3-1%. CT angiography is the choice method for coronary anomalies, but often coronary angiography in RAO (right anterior oblique) view shows the coronary course. We present a case that referred to our hospital with post myocardial infarction angina for coronary angiography. A resting 12-lead electrocardiogram showed ST-segment elevation in leads v2, v3, v4. A transthoracic echocardiogram indicated LVEF 25% (Left ventricular ejection fraction), septal akinesia and apical dyskinesia. Coronary Angiography showed an anomalous origin of the left coronary artery from the right coronary cusp and significant stenosis in LAD (left anterior descending) and LCX (left circumflex) arteries with poor run off.

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Background and Objective: Trauma is the third cause of death and the main cause of disability in Iran. Children are more susceptible to trauma due to physiological conditions and the growth process. This study was done to evaluate the epidemiolog of pediatric trauma in Hamedan, Iran during 2016-2017.

Methods: This descriptive-analytical study was done on 482 traumatic children (330 boys, 152 girls) at the age of 0 to 14 years whom referred to Besat Hospital in Hamedan, Iran during April 2016 to March 2017. Age, gender, season, type of troma and the outcome of trouma were recorded for each subject.

Results: The highest rate of trauma was observed between the ages of 7-14 years old (40.5%). The rate of trauma was significantly higher in boys than the girls (P<0.05). The most rate of trauma occured in summer (36.9%). The most common, place, cause, type, region of traumas were home (44%), falling down (53%), fracture (35%), and region (41%) respectively. Regarding the subsequence of discharge of subjects, 10 deaths and 42 disabilities after trauma were observed.

Conclusion: Regarding the most common type and place of accidents, providing safety at home and knowledge of parents are nesscery for preventing of pediatric teruma in Iran.

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Background and Objective: Perinatal mortality rate (PMR) is one of the main indicators in evaluation of health community and healthcare systems. This study was performed to determine the perinatal mortality rate in the referral third level of maternal and infant care center affiliated to Babol University of Medical Sciences.
Methods: This descriptive-analytical study was performed on by cross-sectional method and 19234 births (9751 male and 9483 female) from 22 weeks gestation to 29 days after delivery Ayatollah Rouhani Hospital in Babol, northern Iran during 2011-18. Data on the cause of neonatal death, maternal age, type of delivery, malformations, maternal underlying disease, maternal pregnancy-related conditions, and diseases at the time of death in neonate were collected from website of the Ministry of Health. Then each of the indicators was calculated per 1000 live births.
Results: In this study, the PMR was calculated per 1000 live births which was 29.01 (boys 16.17 and girls 12.84). The portion of vaginal delivery was 9.67 and cesarean section was 19.34. Out of 558 perinatal deaths, 59.9% died due to intrauterine death with an index of 17.37 and 40.1% of deaths were due to infant death with an index of 11.63. Most neonatal deaths (74%) occurred within the first 24 hours of birth and in terms of gestational age 86.02% were <37 weeks of gestation with an index of 24.95, and low birth weight were 83.8% with an index of 24.31. Underlying disease was found in 25.6% of mothers and pregnancy-related conditions in 74.4% of cases. Fetal distress in 14.4% with an index of 4.20 was the most common disease associated with infant death or cause of death in preterm infants. Other causes of perinatal death were specific disorders of perinatal origin, birth defects, chromosomal abnormalities, and accidents were 10.09, 4.06, and 0.58 per 1000 live births, respectively.
Conclusion: The most and important factors of prenatal mortality wrer prematurity and low birth weight that major causes include maternal pregnancy-related conditions and maternal underlying disease, Therefore, emphasis on adequate prenatal care, identification and follow-up of mothers with underlying diseases can be effective in reducing perinatal mortality.